Osteogenic differentiation and gene expression profile of human dental follicle cells induced by human dental pulp cells

Su‐Jin Park1,2, Hyun-Sook Bae1, Joo‐Cheol Park2
1Department of Dental Hygiene, Namseoul University, Cheonan, South Korea
2Department of Oral Histology-Developmental Biology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, South Korea

Tóm tắt

Từ khóa


Tài liệu tham khảo

Aonuma H et al (2012) Characteristics and osteogenic differentiation of stem/progenitor cells in the human dental follicle analyzed by gene expression profiling. Cell Tissue Res 350:317–331. doi: 10.1007/s00441-012-1477-6

Bai Y, Bai Y, Matsuzaka K, Hashimoto S, Kokubu E, Wang X, Inoue T (2010) Formation of bone-like tissue by dental follicle cells co-cultured with dental papilla cells. Cell Tissue Res 342:221–231. doi: 10.1007/s00441-010-1046-9

Batouli S et al (2003) Comparison of stem-cell-mediated osteogenesis and dentinogenesis. J Dent Res 82:976–981

Beck GR Jr, Zerler B, Moran E (2000) Phosphate is a specific signal for induction of osteopontin gene expression. Proc Natl Acad Sci USA 97:8352–8357. doi: 10.1073/pnas.140021997

Cantinieaux D et al (2013) Conditioned medium from bone marrow-derived mesenchymal stem cells improves recovery after spinal cord injury in rats: an original strategy to avoid cell transplantation. PloS One 8:e69515. doi: 10.1371/journal.pone.0069515

Choung HW, Lee JH, Lee DS, Choung PH, Park JC (2013) The role of preameloblast-conditioned medium in dental pulp regeneration. J Mol Histol 44:715–721. doi: 10.1007/s10735-013-9513-8

Darby I (2011) Periodontal materials Australian dental journal 56(Suppl 1):107–118. doi: 10.1111/j.1834-7819.2010.01301.x

Dowling P, Clynes M (2011) Conditioned media from cell lines: a complementary model to clinical specimens for the discovery of disease-specific biomarkers. Proteomics 11:794–804. doi: 10.1002/pmic.201000530

Felthaus O, Gosau M, Klein S, Prantl L, Reichert TE, Schmalz G, Morsczeck C (2014) Dexamethasone-related osteogenic differentiation of dental follicle cells depends on ZBTB16 but not Runx2. Cell Tissue Res 357:695–705. doi: 10.1007/s00441-014-1891-z

Gronthos S, Mankani M, Brahim J, Robey PG, Shi S (2000) Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA 97:13625–13630. doi: 10.1073/pnas.240309797

Hakki SS, Berry JE, Somerman MJ (2001) The effect of enamel matrix protein derivative on follicle cells in vitro. J Periodontol 72:679–687. doi: 10.1902/jop.2001.72.5.679

Hammarstrom L (1997) Enamel matrix, cementum development and regeneration. J Clin Periodontol 24:658–668

Huang W, Yang S, Shao J, Li YP (2007) Signaling and transcriptional regulation in osteoblast commitment and differentiation. Front Biosci 12:3068–3092

Huang GT, Gronthos S, Shi S (2009) Mesenchymal stem cells derived from dental tissues versus those from other sources: their biology and role in regenerative medicine. J Dent Res 88:792–806. doi: 10.1177/0022034509340867

Inukai T, Katagiri W, Yoshimi R, Osugi M, Kawai T, Hibi H, Ueda M (2013) Novel application of stem cell-derived factors for periodontal regeneration. Biochem Biophys Res Commun 430:763–768. doi: 10.1016/j.bbrc.2012.11.074

Jung HS et al (2011) Directing the differentiation of human dental follicle cells into cementoblasts and/or osteoblasts by a combination of HERS and pulp cells. J Mol Histol 42:227–235. doi: 10.1007/s10735-011-9327-5

Kawai S, Yamauchi M, Wakisaka S, Ooshima T, Amano A (2007) Zinc-finger transcription factor odd-skipped related 2 is one of the regulators in osteoblast proliferation and bone formation. J Bone Miner Res 22:1362–1372. doi: 10.1359/jbmr.070602

Kemoun P et al (2007) Human dental follicle cells acquire cementoblast features under stimulation by BMP-2/-7 and enamel matrix derivatives (EMD) in vitro. Cell Tissue Res 329:283–294. doi: 10.1007/s00441-007-0397-3

Komori T (2002) Runx2, a multifunctional transcription factor in skeletal development. J Cell Biochem 87:1–8. doi: 10.1002/jcb.10276

Kruzynska-Frejtag A et al (2004) Periostin is expressed within the developing teeth at the sites of epithelial-mesenchymal interaction. Dev Dyn 229:857–868. doi: 10.1002/dvdy.10453

Lan Y, Ovitt CE, Cho ES, Maltby KM, Wang Q, Jiang R (2004) Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development 131:3207–3216. doi: 10.1242/dev.01175

Li LF et al (2013) Improvement of ventilator-induced lung injury by IPS cell-derived conditioned medium via inhibition of PI3 K/Akt pathway and IP-10-dependent paracrine regulation. Biomaterials 34:78–91. doi: 10.1016/j.biomaterials.2012.09.042

Lim JM, Lee M, Lee EJ, Gong SP, Lee ST (2011) Stem cell engineering: limitation, alternatives, and insight. Ann N Y Acad Sci 1229:89–98. doi: 10.1111/j.1749-6632.2011.06093.x

Matsubara T et al (2008) BMP2 regulates osterix through Msx2 and Runx2 during osteoblast differentiation. J Biol Chem 283:29119–29125. doi: 10.1074/jbc.M801774200

Miura M, Gronthos S, Zhao M, Lu B, Fisher LW, Robey PG, Shi S (2003) SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA 100:5807–5812. doi: 10.1073/pnas.0937635100

Morsczeck C et al (2005) Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth. Matrix Biol 24:155–165. doi: 10.1016/j.matbio.2004.12.004

Morsczeck C, Schmalz G, Reichert TE, Vollner F, Galler K, Driemel O (2008) Somatic stem cells for regenerative dentistry. Clin Oral Invest 12:113–118. doi: 10.1007/s00784-007-0170-8

Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B (2002) The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108:17–29

Osugi M, Katagiri W, Yoshimi R, Inukai T, Hibi H, Ueda M (2012) Conditioned media from mesenchymal stem cells enhanced bone regeneration in rat calvarial bone defects. Tissue Eng Part A 18:1479–1489. doi: 10.1089/ten.TEA.2011.0325

Papaccio G et al (2006) Long-term cryopreservation of dental pulp stem cells (SBP-DPSCs) and their differentiated osteoblasts: a cell source for tissue repair. J Cell Physiol 208:319–325. doi: 10.1002/jcp.20667

Pihlstrom BL, Michalowicz BS, Johnson NW (2005) Periodontal diseases Lancet 366:1809–1820. doi: 10.1016/S0140-6736(05)67728-8

Ratka-Kruger P, Neukranz E, Raetzke P (2000) Guided tissue regeneration procedure with bioresorbable membranes versus conventional flap surgery in the treatment of infrabony periodontal defects. J Clin Periodontol 27:120–127

Sabatakos G et al (2000) Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis. Nat Med 6:985–990. doi: 10.1038/79683

Seo BM et al (2004) Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 364:149–155. doi: 10.1016/S0140-6736(04)16627-0

Snead ML (2008) Whole-tooth regeneration: it takes a village of scientists, clinicians, and patients. J Dent Educ 72:903–911

Sonoyama W et al (2006) Mesenchymal stem cell-mediated functional tooth regeneration in swine. PloS One 1:e79. doi: 10.1371/journal.pone.0000079

Takahashi K, Ogura N, Aonuma H, Ito K, Ishigami D, Kamino Y, Kondoh T (2013) Bone morphogenetic protein 6 stimulates mineralization in human dental follicle cells without dexamethasone. Arch Oral Biol 58:690–698. doi: 10.1016/j.archoralbio.2012.10.018

Takeda T et al (2008) Characterization of dental pulp stem cells of human tooth germs. J Dent Res 87:676–681

Ten Cate AR (1997) The development of the periodontium–a largely ectomesenchymally derived unit. Periodontology 2000(13):9–19

Tziafas D, Kodonas K (2010) Differentiation potential of dental papilla, dental pulp, and apical papilla progenitor cells. J Endodont 36:781–789. doi: 10.1016/j.joen.2010.02.006

Villar CC, Cochran DL (2010) Regeneration of periodontal tissues: guided tissue regeneration. Dent Clin North Am 54:73–92. doi: 10.1016/j.cden.2009.08.011

Wight TN (2002) Versican: a versatile extracellular matrix proteoglycan in cell biology. Curr Opin Cell Biol 14:617–623

Wu J et al (2008) Dentin non-collagenous proteins (dNCPs) can stimulate dental follicle cells to differentiate into cementoblast lineages. Biol Cell 100:291–302. doi: 10.1042/BC20070092

Xu T et al (2014) Estrogen deficiency reduces the dentinogenic capacity of rat lower incisors. J Mol Histol 45:11–19. doi: 10.1007/s10735-013-9533-4

Yamamura T (1985) Differentiation of pulpal cells and inductive influences of various matrices with reference to pulpal wound healing. J Dent Res 64:530–540

Yang Y et al (2014) Hertwig’s epithelial root sheath cells regulate osteogenic differentiation of dental follicle cells through the Wnt pathway. Bone 63:158–165. doi: 10.1016/j.bone.2014.03.006

Yavropoulou MP, Yovos JG (2007) The role of the Wnt signaling pathway in osteoblast commitment and differentiation. Hormones 6:279–294

Zhang C (2010) Transcriptional regulation of bone formation by the osteoblast-specific transcription factor Osx. J Orthop Surg Res 5:37. doi: 10.1186/1749-799X-5-37

Zhang Z, Song Y, Zhang X, Tang J, Chen J, Chen Y (2003) Msx1/Bmp4 genetic pathway regulates mammalian alveolar bone formation via induction of Dlx5 and Cbfa1. Mech Dev 120:1469–1479

Zhang Q, Shi S, Liu Y, Uyanne J, Shi Y, Shi S, Le AD (2009a) Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis. J Immunol 183:7787–7798. doi: 10.4049/jimmunol.0902318

Zhang Z, Lan Y, Chai Y, Jiang R (2009b) Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row. Science 323:1232–1234. doi: 10.1126/science.1167418

Zhao M, Xiao G, Berry JE, Franceschi RT, Reddi A, Somerman MJ (2002) Bone morphogenetic protein 2 induces dental follicle cells to differentiate toward a cementoblast/osteoblast phenotype. J Bone Miner Res 17:1441–1451. doi: 10.1359/jbmr.2002.17.8.1441

Zhong Z et al (2012) Wntless functions in mature osteoblasts to regulate bone mass. Proc Natl Acad Sci USA 109:E2197–E2204. doi: 10.1073/pnas.1120407109