The HMGB1-RAGE axis mediates traumatic brain injury–induced pulmonary dysfunction in lung transplantation

American Association for the Advancement of Science (AAAS) - Tập 6 Số 252 - 2014
Daniel Weber1,2, Adam Gracon1,2, Matthew S. Ripsch3, Amanda Fisher1,3, Bo M. Cheon3, Pankita H. Pandya1,4, Ragini Vittal1,4, Maegan L. Capitano4, Young‐Sook Kim3, Yohance M. Allette3, Amanda A. Riley5, Brian P. McCarthy5, Paul R. Territo5, Gary D. Hutchins5, Hal E. Broxmeyer4, George E. Sandusky6, Fletcher A. White1,3, David S. Wilkes1,4
1Center for Immunobiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
2Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
3Department of Anesthesia, Paul and Carole Stark Neurosciences Research Institute, Indianapolis, IN 46202, USA.
4Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
5Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46202, USA
6Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA

Tóm tắt

Traumatic brain injury induces acute lung injury that negatively impacts the physiology of the donor lung before and after lung transplantation.

Từ khóa


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American Association for the Advancement of Science (AAAS)

Tập 6 Số 252

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