Alcohol drinking determines the effect of the APOE locus on LDL-cholesterol concentrations in men: the Framingham Offspring Study

Eichner, 1990, Phenotypic effects of apolipoprotein structural variation on lipid profiles. III. Contribution of apolipoprotein E phenotype to prediction of total cholesterol, apolipoprotein B, and low density lipoprotein cholesterol in the healthy women stud, Arteriosclerosis, 10, 379, 10.1161/01.ATV.10.3.379 Boerwinkle, 1988, Simultaneous effects of the apolipoprotein E polymorphism on apolipoprotein E, apolipoprotein B, and cholesterol metabolis, Am J Hum Genet, 42, 104 Wilson, 1994, Apolipoprotein E alleles, dyslipidemia, and coronary heart disease: The Framingham Offspring Stud, JAMA, 272, 1666, 10.1001/jama.1994.03520210050031 Braeckman, 1996, Apolipoprotein E polymorphism in middle-aged Belgian men: phenotype distribution and relation to serum lipids and lipoprotein, Atherosclerosis, 120, 67, 10.1016/0021-9150(95)05681-5 Jarvik, 1994, Genetic influences on age-related change in total cholesterol, low density lipoprotein cholesterol, and triglyceride levels: longitudinal apolipoprotein E genotype effect, Genet Epidemiol, 11, 375, 10.1002/gepi.1370110407 Pablos-Mendez, 1997, Association of apo E polymorphism with plasma lipid levels in a multiethnic elderly populatio, Arterioscler Thromb Vasc Biol, 17, 3534, 10.1161/01.ATV.17.12.3534 Aguilar, 1999, The apolipoprotein E4 allele is not associated with an abnormal lipid profile in a Native American population following its traditional lifestyl, Atherosclerosis, 142, 409, 10.1016/S0021-9150(98)00251-2 Lopez-Miranda, 1994, Effect of apolipoprotein E phenotype on diet-induced lowering of plasma low density lipoprotein cholestero, J Lipid Res, 35, 1965, 10.1016/S0022-2275(20)39943-0 Lehtimaki, 1997, The effect of short-term fasting, apolipoprotein E gene polymorphism, and sex on plasma lipid, Am J Clin Nutr, 66, 599, 10.1093/ajcn/66.3.599 Kiechl, 1998, Alcohol consumption and atherosclerosis: what is the relation? Prospective results from the Bruneck Stud, Stroke, 29, 900, 10.1161/01.STR.29.5.900 McElduff, 1997, How much alcohol and how often? Population based case-control study of alcohol consumption and risk of a major coronary even, BMJ, 314, 1159, 10.1136/bmj.314.7088.1159 Gronbaek, 1998, Alcohol and mortality: is there a U-shaped relation in elderly people, Age Ageing, 27, 739, 10.1093/ageing/27.6.739 Renaud, 1998, Alcohol and mortality in middle-aged men from eastern Franc, Epidemiology, 9, 184, 10.1097/00001648-199803000-00014 Keil, 1997, The relation of alcohol intake to coronary heart disease and all-cause mortality in a beer-drinking populatio, Epidemiology, 8, 150, 10.1097/00001648-199703000-00005 Rimm, 1996, Review of moderate alcohol consumption and reduced risk of coronary heart disease: is the effect due to beer, wine, or spirit, BMJ, 312, 731, 10.1136/bmj.312.7033.731 Glueck, 1980, Effects of alcohol ingestion on lipids and lipoproteins in normal men: isocaloric metabolic studie, Am J Clin Nutr, 33, 2287, 10.1093/ajcn/33.11.2287 Gaziano, 1993, Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infarctio, N Engl J Med, 329, 1829, 10.1056/NEJM199312163292501 Rimm, 1999, Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factor, BMJ, 319, 1523, 10.1136/bmj.319.7224.1523 Vasisht, 1992, Effect of alcohol on serum lipids & lipoproteins in male drinker, Indian J Med Res, 96, 333 Langer, 1992, Lipoproteins and blood pressure as biological pathways for effect of moderate alcohol consumption on coronary heart diseas, Circulation, 85, 910, 10.1161/01.CIR.85.3.910 Nakanishi, 1999, Relationship between lifestyle and serum lipid and lipoprotein levels in middle-aged Japanese me, Eur J Epidemiol, 15, 341, 10.1023/A:1007527111946 McConnell, 1997, Effects of a single, daily alcoholic beverage on lipid and hemostatic markers of cardiovascular ris, Am J Cardiol, 80, 1226, 10.1016/S0002-9149(97)00647-4 Rakic, 1998, A controlled trial of the effects of pattern of alcohol intake on serum lipid levels in regular drinker, Atherosclerosis, 137, 243, 10.1016/S0021-9150(97)00269-4 Hein, 1996, Alcohol consumption, serum low density lipoprotein cholesterol concentration, and risk of ischaemic heart disease: six year follow up in the Copenhagen male stud, BMJ, 312, 736, 10.1136/bmj.312.7033.736 Feinleib, 1975, The Framingham Offspring Study. Design and preliminary dat, Prev Med, 4, 518, 10.1016/0091-7435(75)90037-7 Kannel, 1979, An investigation of coronary heart disease in families: the Framingham Offspring Stud, Am J Epidemiol, 110, 281, 10.1093/oxfordjournals.aje.a112813 Dawber, 1951, Epidemiological approaches to heart disease: The Framingham Stud, Am J Public Health, 41, 279, 10.2105/AJPH.41.3.279 Cupples, 1992, Long- and short-term risk of sudden coronary deat, Circulation, 85, 111 Warnick, 1982, Dextran sulfate-Mg precipitation procedure for quantitation of high density lipoprotein cholestero, Clin Chem, 28, 1379, 10.1093/clinchem/28.6.1379 Friedewald, 1972, Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of preparative ultracentrifug, Clin Chem, 18, 499, 10.1093/clinchem/18.6.499 McNamara, 1987, Automated enzymatic standardized lipid analyses for plasma and apolipoprotein fraction, Clin Chim Acta, 166, 1, 10.1016/0009-8981(87)90188-4 Miller, 1989, A simple salting out procedure for extracting DNA from human nucleated cell, Nucleic Acids Res, 16, 1215, 10.1093/nar/16.3.1215 Hixson, 1990, Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hha, J Lipid Res, 31, 545, 10.1016/S0022-2275(20)43176-1 Willett, 1985, Reproducibility and validity of a semiquantitative food frequency questionnair, Am J Epidemiol, 122, 51, 10.1093/oxfordjournals.aje.a114086 Tucker, 2000, Plasma vitamin B-12 concentrations relate to intake source in the Framingham Offspring stud, Am J Clin Nutr, 71, 514, 10.1093/ajcn/71.2.514 Pearson, 1996, Alcohol and heart diseas, Circulation, 94, 3023, 10.1161/01.CIR.94.11.3023 Cannings, 1969, Expected genotypic frequencies in a small sample: deviation from Hardy-Weinberg equilibriu, Am J Hum Genet, 21, 245 Sing, 1985, Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variatio, Am J Clin Genet, 37, 268 Ordovas, 1999, The genetics of serum lipid responsiveness to dietary intervention, Proc Nutr Soc, 58, 171, 10.1079/PNS19990023 Lefevre, 1997, ApoE genotype does not predict lipid response to changes in dietary saturated fatty acids in a heterogeneous normolipidemic population. The DELTA Research Group. Dietary effects on lipoproteins and thrombogenic activit, Arterioscler Thromb Vasc Biol, 17, 2914, 10.1161/01.ATV.17.11.2914 Kamboh, 1991, Genetic studies of human apolipoproteins. XVI. APOE polymorphism and cholesterol levels in the Mayans of the Yucatan Peninsula, Mexic, Clin Genet, 39, 26, 10.1111/j.1399-0004.1991.tb02981.x Deiana, 1998, Lack of influence of apolipoprotein E4 on lipoprotein levels in the island population of Sardini, Eur J Clin Invest, 28, 290, 10.1046/j.1365-2362.1998.00271.x Sandholzer, 1995, High frequency of the apo epsilon 4 allele in Khoi San from South Afric, Hum Genet, 95, 46, 10.1007/BF00225073 Zerba, 1996, Genotype-environment interaction: apolipoprotein E ( ApoE ) gene effects and age as an index of time and spatial context in the huma, Genetics, 143, 463, 10.1093/genetics/143.1.463 Davignon, 1988, Apolipoprotein E polymorphism and atherosclerosi, Arteriosclerosis, 8, 1, 10.1161/01.ATV.8.1.1 Whichelow, 1996, Dietary patterns and their associations with demographic, lifestyle and health variables in a random sample of British adult, Br J Nutr, 76, 17, 10.1079/BJN19960006 Posner, 1993, Diet, menopause, and serum cholesterol levels in women: The Framingham Stud, Am Heart J, 125, 483, 10.1016/0002-8703(93)90030-D Shaper, 1998, The J-shaped curve and changes in drinking habi, Novartis Found Symp, 216, 173 Greenfield, 1999, Who drinks most of the alcohol in the US? The policy implication, J Stud Alcohol, 60, 78, 10.15288/jsa.1999.60.78 Okada, 1998, Relationship of apolipoprotein E phenotypes to serum lipid and lipoprotein levels in Japanese schoolchildre, Acta Paediatr, 87, 460, 10.1111/j.1651-2227.1998.tb01480.x Lehtimäki, 1994, Apolipoprotein E phenotypes and serum lipids in newborns and 3-year-old children: the Cardiovascular Risk in Young Finns Stud, Pediatrics, 94, 489, 10.1542/peds.94.4.489 Dixon, 1997, Effects of family history of heart disease, apolipoprotein E phenotype, and lipoprotein(a) on the response of children’s plasma lipids to change in dietary lipid, Am J Clin Nutr, 66, 1207, 10.1093/ajcn/66.5.1207 Bercedo, 1998, Association between lipid profile and Apo E genotype in Spanish children (8–15 years old), Ann Esp Pediatr, 42, 120 Kauma, 1998, Apolipoprotein E phenotype determines the effect of alcohol on blood pressure in middle-aged me, Am J Hypertens, 11, 1334, 10.1016/S0895-7061(98)00163-0 Lin, 1995, Concentrations of apolipoprotein AI, AII, and E in plasma and lipoprotein fractions of alcoholic patients: gender differences in the effects of alcoho, Hepatology, 21, 942 Higuchi, 1990, Plasma lipid and lipoprotein profiles in pre- and post-menopausal middle-aged runner, Clin Physiol, 10, 69, 10.1111/j.1475-097X.1990.tb00084.x Garry, 1999, Estrogen replacement therapy, serum lipids, and polymorphism of the apolipoprotein E gen, Clin Chem, 45, 1214, 10.1093/clinchem/45.8.1214 Jones, 1988, Menstrual cycle effect on plasma lipid, Metabolism, 37, 1, 10.1016/0026-0495(88)90020-0 Hegele, 1994, A gene-gender interaction affecting plasma lipoproteins in a genetic isolat, Arterioscler Thromb, 14, 671, 10.1161/01.ATV.14.5.671 Posner, 1992, Comparison of the techniques for estimating nutrient intake: The Framingham Stud, Epidemiology, 3, 171, 10.1097/00001648-199203000-00016 Romelsjo, 1995, A comparative study of two methods for the measurement of alcohol consumption in the general populatio, Int J Epidemiol, 24, 929, 10.1093/ije/24.5.929 Shaper, 1990, Alcohol and mortality: a review of prospective studie, Br J Addict, 85, 837, 10.1111/j.1360-0443.1990.tb03710.x Colditz, 1991, Alcohol intake in relation to diet and obesity in women and me, Am J Clin Nutr, 54, 49, 10.1093/ajcn/54.1.49 Mannisto, 1997, Alcohol beverage drinking, diet and body mass index in a cross-sectional surve, Eur J Clin Nutr, 51, 326, 10.1038/sj.ejcn.1600406 Wannamethee, 1992, Blood lipids: the relationship with alcohol intake, smoking, and body weigh, J Epidemiol Community Health, 46, 197, 10.1136/jech.46.3.197 Bottoni, 1997, Lifestyle and dietary differences in smokers and non-smokers from an Italian employee populatio, Public Health, 111, 161, 10.1016/S0033-3506(97)00576-3 Frohlich, 1996, Effects of alcohol on plasma lipoprotein metabolis, Clin Chim Acta, 246, 39, 10.1016/0009-8981(96)06225-0 Liinamaa, 1997, Altered transfer of cholesteryl esters and phospholipids in plasma from alcohol abuser, Arterioscler Thromb Vasc Biol, 17, 2940, 10.1161/01.ATV.17.11.2940 Simon, 1996, Relation of smoking and alcohol consumption to serum fatty acid, Am J Epidemiol, 144, 325, 10.1093/oxfordjournals.aje.a008933 Hirano, 1992, Low-density lipoproteins in hyperalphalipoproteinemic heavy alcohol drinkers have reduced affinity for the low-density lipoprotein recepto, Clin Biochem, 25, 357, 10.1016/0009-9120(92)80016-A Nishiwaki, 1994, Effects of alcohol on lipoprotein lipase, hepatic lipase, cholesteryl ester transfer protein, and lecithin:cholesterol acyltransferase in high-density lipoprotein cholesterol elevatio, Atherosclerosis, 111, 99, 10.1016/0021-9150(94)90195-3 Ayaori, 1997, Beneficial effects of alcohol withdrawal on LDL particle size distribution and oxidative susceptibility in subjects with alcohol-induced hypertriglyceridemi, Arterioscler Thromb Vasc Biol, 17, 2540, 10.1161/01.ATV.17.11.2540 Hendriks, 1998, Moderate doses of alcoholic beverages with dinner and postprandial high density lipoprotein compositio, Alcohol, 33, 403, 10.1093/oxfordjournals.alcalc.a008410 Van Tol, 1998, Changes in postprandial lipoproteins of low and high density caused by moderate alcohol consumption with dinne, Atherosclerosis, 141, S101, 10.1016/S0021-9150(98)00226-3