Regulation of alternative splicing in the amyloid precursor protein (APP) mRNA during neuronal and glial differentiation of P19 embryonal carcinoma cells

Chomczynski, 1987, Single-step method of RNA isolation by acid guanidium thiocyanate-PhOH-chloroform extraction, Anal. Biochem., 162, 156, 10.1016/0003-2697(87)90021-2 Chartier-Harlin, 1991, Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene, Nature, 353, 844, 10.1038/353844a0 Ge, 1990, A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro, Cell, 62, 25, 10.1016/0092-8674(90)90236-8 Ge, 1991, Primary structure of the human splicing factor ASF reveals similarities withDrosophila regulators, Cell, 66, 373, 10.1016/0092-8674(91)90626-A Goate, 1991, Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease, Nature, 349, 704, 10.1038/349704a0 Golde, 1990, Expression of β amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR, Neuron, 4, 253, 10.1016/0896-6273(90)90100-T Kang, 1987, The precursor of Alzheimer's disease amyloid A4 protein resembles a cell surface receptor, Nature, 325, 733, 10.1038/325733a0 Kitaguchi, 1988, Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity, Nature, 331, 530, 10.1038/331530a0 Krainer, 1990, The essential pre-mRNA splicing factor SF2 influences 5′ splice site selection by activating proximal sites, Cell, 62, 35, 10.1016/0092-8674(90)90237-9 Krainer, 1991, Functional expression of cloned human splicing factor SF2: Homology to RNA-binding proteins, U1 70K, andDrosophila splicing regulators, Cell, 66, 383, 10.1016/0092-8674(91)90627-B Mulligan, 1992, Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of β-tropomyosin pre-mRNA, J. Biol. Chem., 267, 25480, 10.1016/S0021-9258(19)74066-6 Murrell, 1991, A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease, Science, 254, 97, 10.1126/science.1925564 Naruse, 1991, Mis-sense mutation Val—Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease, Lancet, 337, 978, 10.1016/0140-6736(91)91612-X Patton, 1991, Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing, Genes Dev., 5, 1237, 10.1101/gad.5.7.1237 Patton, 1993, Cloning and characterization of PSF, a novel pre-mRNA splicing factor, Genes Dev., 7, 393, 10.1101/gad.7.3.393 Ponte, 1988, A new A4 amyloid mRNA contains a domain homologous to serine protease inhibitors, Nature, 331, 525, 10.1038/331525a0 Reynolds, 1994, Neurons derived from embryonal carcinoma (P19) cells express multiple GABAA receptor subunits and fully functional GABAA receptors, Neurosci. Lett., 165, 129, 10.1016/0304-3940(94)90726-9 Rudnicki, 1987, Cell culture method and induction of differentiation of embryonal carcinoma cell lines Sambrook, 1989 Sandbrink, 1994, β A4-amyloid protein precursor mRNA isoforms without exon 15 are ubiquitously expressed in rat tissues including brain, but not in neurons, J. Biol. Chem., 269, 1510, 10.1016/S0021-9258(17)42286-1 Stamm, 1994, A sequence compilation and comparison of exons that are alternatively spliced in neurons, Nucleic Acids Res., 22, 1515, 10.1093/nar/22.9.1515 Tanzi, 1988, Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease, Nature, 331, 528, 10.1038/331528a0 Tsukahara, 1994, Alternative splicing of β-tropomyosin pre-mRNA: multiplecis-elements can contribute to the use of the 5′- and 3′-splice sites of the nonmuscle/smooth muscle exon 6, Nucleic Acids Res., 22, 2318, 10.1093/nar/22.12.2318 Valcarcel, 1993, The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA, Nature, 362, 171, 10.1038/362171a0 Yamada, 1987, Complementary DNA for the mouse homolog of the human amyloid beta protein precursor, Biochem. Biophys. Res. Commun., 149, 665, 10.1016/0006-291X(87)90419-0 Yoshikai, 1990, Genomic organization of the human amyloid β-protein precursor gene, Gene, 87, 257, 10.1016/0378-1119(90)90310-N Yoshikawa, 1990, Neural differentiation increase expression of Alzheimer amyloid protein precursor gene in murine embryonal carinoma cells, Biochem. Biophys. Res. Commun., 171, 204, 10.1016/0006-291X(90)91377-5 Zamore, 1992, Cloning and domain structure of the mammalian splicing factor U2AF, Nature, 355, 609, 10.1038/355609a0