Involvement of HIF-1 in Invasion of Mum2B Uveal Melanoma Cells

Perlis C, Herlyn M (1998) Recent advances in melanoma biology. Oncologist 9:182–187 Makitie T, Jager MJ, Kivela T (2004) Prognostic indicators in choroidal and ciliary body melanoma. In: Jager MJ, Niederkorn JY, Ksander BR (eds) Uveal melanoma: a model for exploring fundamental cancer biology. Taylor and Francis Press, pp 1–31 Hendrix MJC, Seftor EA, Hess AR et al (2003) Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma. Nat Rev Cancer 3:411–421 Hess AR, Seftor EA, Gardner LM et al (2001) Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2). Cancer Res 61:3250–3255 Seftor EA, Meltzer PS, Kirschmann DA et al (2002) Molecular determinants of human uveal melanoma invasion and metastasis. Clin Exp Metastasis 19:233–246 Brown JM, Giaccia AJ (1998) The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 58:1408–1416 Brown JM, Wilson WR (2004) Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 6:437–447 Ceradini DJ, Kulkarni AR, Callaghan MJ et al (2004) Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 10:858–864 Cowden Dahl KD, Robertson SE, Weaver VM et al (2005) Hypoxia-inducible factor regulates alpha v beta3 integrin cell surface expression. Mol Biol Cell 16:1901–1912 Krishnamachary B, Berg-Dixon S, Kelly B et al (2003) Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1. Cancer Res 63:1138–1143 Zagzag D, Zhong H, Scalzitti JM et al (2000) Expression of hypoxia-inducible factor 1α in brain tumors: association with angiogenesis, invasion, and progression. Cancer 88:2606–2618 Pennacchietti S, Michieli P, Galluzzo M et al (2003) Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell 3:347–361 Zhong H, De Marzo AM, Laughner E et al (1999) Overexpression of hypoxia-inducible factor 1 alpha in common human cancers and their metastases. Cancer Res 59:5830–5835 Semenza GL, Wang GL (1992) A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12:5447–5454 Wang GL, Semenza GL (1995) Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 270:1230–1237 Maxwell PH, Wiesener MS, Chang GW et al (1999) The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399:271–275 Ohh M, Park CW, Ivan M et al (2000) Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nat Cell Biol 2:423–427 Salceda S, Caro J (1997) Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J Biol Chem 272:22642–22647 Huang LE, Gu J, Schau M et al (1998) Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci USA 95:7987–7992 Ivan M, Kondo K, Yang H et al (2001) HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 292:464–468 Jaakkola P, Mole DR, Tian YM et al (2001) Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292:468–472 Semenza GL (2003) Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3:721–732 Carmeliet P, Dor Y, Herbert JM et al (1998) Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394:485–490 Ryan HE, Lo J, Johnson RS (1998) HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J 17:3005–3015 Schioppa T, Uranchimeg B, Saccani A et al (2003) Regulation of the chemokine receptor CXCR4 by hypoxia. J Exp Med 198:1391–1402 Staller P, Sulitkova J, Lisztwan J et al (2003) Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL. Nature 425:307–311 Phillips RJ, Mestas J, Gharaee-Kermani M et al (2004) Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia-inducible factor-1 alpha. J Biol Chem 280:22473–22481 Le Jan S, Amy C, Cazes A et al (2003) Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma. Am J Pathol 162(5):1521–1528 Yeung HY, Lai KP, Chan HY et al (2005) Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells. Endocrinology 146:4951–4960 Zatyka M, Fernandes N, Clifford SC et al (2002) Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease. Cancer Res 62:3803–3811 Venstrom K, Reichardt L (1995) Beta 8 integrins mediate interactions of chick sensory neurons with laminin-1, collagen IV, and fibronectin. Mol Biol Cell 6:419–431 Iyer NV, Kotch LE, Agani F et al (1998) Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 12:149–162 Reshkin J, Bellizzi A, Albarani V et al (2000) Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na+/H+ exchange, motility, and invasion induced by serum deprivation. J Biol Chem 275:5361–5369 Maniotis AJ, Folberg R, Hess A et al (1999) Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. Am J Pathol 155:739–752 McDonald DM, Munn L, Jain RK (2000) Vasculogenic mimicry: how convincing, how novel, and how significant? Am J Pathol 156:383–388 Maniotis AJ, Chen X, Garcia C et al (2002) Control of melanoma morphogenesis, endothelial survival, and perfusion by extracellular matrix. Lab Invest 82:1031–1043 Chen X, Maniotis AJ, Majumdar D et al (2002) Uveal melanoma cell staining for CD34 and assessment of tumor vascularity. Invest Ophthalmol Vis Sci 43:2533–2539 Shirakawa K, Kobayashi H, Heike Y et al (2002) Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft. Cancer Res 62:560–566 Clarijs R, Otte-Holler I, Ruiter DJ et al (2002) Presence of a fluid-conducting meshwork in xenografted cutaneous and primary human uveal melanoma. Invest Ophthalmol Vis Sci 43:912–918 Mizukami Y, Jo WS, Duerr EM et al (2005) Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells. Nat Med 11:992–997 Kvanta A, Steen B, Seregard S et al (1996) Expression of vascular endothelial growth factor (VEGF) in retinoblastoma but not in posterior uveal melanoma. Exp Eye Res 63:511–518 Sheidow TG, Hooper PL, Crukley C et al (2000) Expression of vascular endothelial growth factor in uveal melanoma and its correlation with metastasis. Br J Ophthalmol 84:750– 756 Westphal JR, Van’t Hullenar R, Peek R et al (2000) Angiogenic balance in human melanoma: expression of VEGF, bFGF, IL-8, PDGF and angiostatin in relation to vascular density of xenografts invivo. Int J Cancer 86:768–776 Boyd S (2004) Uveal melanoma, angiogenesis. In: Jager MJ, Niederkorn JY, Ksander BR (eds) Uveal melanoma: a model for exploring fundamental cancer biology. Taylor and Francis Press, pp 125–155 Folberg R, Rummelt V, Parys-Van Ginderdeuren R et al (1993) The prognostic value of tumor blood vessel morphology in primary uveal melanoma. Ophthalmology 100:1389–1398 Makitie T, Summanen P, Tarkkanen A et al (1999) Microvascular loops and networks as prognostic indicators in choroidal and ciliary body melanomas. J Natl Cancer Inst 91:359–367 Sakamoto T, Sakamoto M, Yoshikawa H et al (1996) Histologic findings and prognosis of uveal malignant melanoma in Japanese patients. Am J Ophthalmol 121:276–283 Seregard S, Spangberg B, Juul C et al (1998) Prognostic accuracy of the mean of the largest nucleoli, vascular patterns, and PC-10 in posterior uveal melanoma. Ophthalmology 105:485–491 Thies A, Mangold U, Moll I et al (2001) PAS-positive loops and networks as a prognostic indicator in cutaneous malignant melanoma. J Pathol 195:537–542 Rummelt V, Mehaffey MG, Campbell RJ et al (1998) Microcirculation architecture of metastases from primary ciliary body and choroidal melanomas. Am J Ophthalmol 126:303–305