Regenerative Medicine: Past and Present

Aebischer, P., T.K. Ip, L. Miracoli, and P.M. Galletti. 1987a. Renal epithelial cells grown on semipermeable hollow fibers as a potential ultrafiltrate processor. ASAIO Transactions 33(3): 96–102. Aebischer, P., T.K. Ip, G. Panol, and P.M. Galletti. 1987b. The bioartificial kidney: Progress towards an ultrafiltration device with renal epithelial cells processing. Life Support Systems 5(2): 159–168. Amiel, G.E., and A. Atala. 1999. Current and future modalities for functional renal replacement. Urologic Clinics of North America 26(1): 235–246. Amiel, G.E., J.J. Yoo, and A. Atala. 2000. Renal therapy using tissue-engineered constructs and gene delivery. World Journal of Urology 18(1): 71–79. Amiel, G.E., et al. 2006. Engineering of blood vessels from acellular collagen matrices coated with human endothelial cells. Tissue Engineering 12(8): 2355–2365. Amit, M., C. Shariki, V. Margulets, and J. Itskovitz-Eldor. 2004. Feeder layer- and serum-free culture of human embryonic stem cells. Biology of Reproduction 70(3): 837–845. Arora, P.D., M.F. Manolson, G.P. Downey, J. Sodek, and C.A.G. McCulloch. 2000. A Novel Model System for Characterization of Phagosomal Maturation, Acidification, and Intracellular Collagen Degradation in Fibroblasts. Journal of Biological Chemistry 275(45): 35432–35441. Assady, S., G. Maor, M. Amit, J. Itskovitz-Eldor, K.L. Skorecki, and M. Tzukerman. 2001. Insulin production by human embryonic stem cells. Diabetes 50(8): 1691–1697. Atala, A. 1998. Autologous cell transplantation for urologic reconstruction. Journal of Urology 159(1): 2–3. Atala, A. 1999. Creation of bladder tissue in vitro and in vivo. A system for organ replacement. Advances in Experimental Medicine and Biology 462: 31–42. Atala, A. 2001. Bladder regeneration by tissue engineering. BJU International 88(7): 765–770. Atala, A. 2002. Experimental and clinical experience with tissue engineering techniques for urethral reconstruction. Urologic Clinics of North America 29(2): 485–492. Atala, A., S.B. Bauer, S. Soker, J.J. Yoo, and A.B. Retik. 2006. Tissue-engineered autologous bladders for patients needing cystoplasty. Lancet 367(9518): 1241–1246. Atala, A., M.R. Freeman, J.P. Vacanti, J. Shepard, and A.B. Retik. 1993a. Implantation in vivo and retrieval of artificial structures consisting of rabbit and human urothelium and human bladder muscle. Journal of Urology 150(2 Pt 2): 608–612. Atala, A., W. Kim, K.T. Paige, C.A. Vacanti, and A.B. Retik. 1994. Endoscopic treatment of vesicoureteral reflux with a chondrocyte-alginate suspension. Journal of Urology 152(2 Pt 2): 641–643; discussion 644. Atala, A., J.P. Vacanti, C.A. Peters, J. Mandell, A.B. Retik, and M.R. Freeman. 1992. Formation of urothelial structures in vivo from dissociated cells attached to biodegradable polymer scaffolds in vitro. Journal of Urology 148(2 Pt 2): 658–662. Atala, A., et al. 1993b. Injectable alginate seeded with chondrocytes as a potential treatment for vesicoureteral reflux. Journal of Urology 150(2 Pt 2): 745–747. Auchincloss, H., and J.V. Bonventre. 2002. Transplanting cloned cells into therapeutic promise. Nature Biotechnology 20(7): 665–666. Baguisi, A., et al. 1999. Production of goats by somatic cell nuclear transfer. Nature Biotechnology 17(5): 456–461. Bent, A.E., R.T. Tutrone, M.T. McLennan, L.K. Lloyd, M.J. Kennelly, and G. Badlani. 2001. Treatment of intrinsic sphincter deficiency using autologous ear chondrocytes as a bulking agent. Neurourology and Urodynamics 20(2): 157–165. Bergsma, J.E., F.R. Rozema, R.R. Bos, G. Boering, W.C. de Bruijn, and A.J. Pennings. 1995. In vivo degradation and biocompatibility study of in vitro pre-degraded as-polymerized polyactide particles. Biomaterials 16(4): 267–274. Betthauser, J., et al. 2000. Production of cloned pigs from in vitro systems. Nature Biotechnology 18(10): 1055–1059. Bhandari, R.N., et al. 2001. Liver tissue engineering: a role for co-culture systems in modifying hepatocyte function and viability. Tissue Engineering 7(3): 345–357. Blelloch, R., Z. Wang, A. Meissner, S. Pollard, A. Smith, and R. Jaenisch. 2006. Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus 1. Stem Cells 24(9): 2007–2013. Brivanlou, A.H., F.H. Gage, R. Jaenisch, T. Jessell, D. Melton, and J. Rossant. 2003. Stem cells. Setting standards for human embryonic stem cells. Science 300(5621): 913–916. Buckwalter, J.A., and S. Lohmander. 1994. Operative treatment of osteoarthrosis. Current practice and future development. Journal of Bone & Joint Surgery – American Volume 76(9): 1405–1418. Buckwalter, J.A., and H.J. Mankin. 1998. Articular cartilage repair and transplantation. Arthritis and Rheumatism 41(8): 1331–1342. Campbell, K.H., J. McWhir, W.A. Ritchie, and I. Wilmut. 1996. Sheep cloned by nuclear transfer from a cultured cell line. Nature 380(6569): 64–66. Chancellor, M.B., et al. 2000. Preliminary results of myoblast injection into the urethra and bladder wall: A possible method for the treatment of stress urinary incontinence and impaired detrusor contractility. Neurourology and Urodynamics 19(3): 279–287. Chen, F., J.J. Yoo, and A. Atala. 1999. Acellular collagen matrix as a possible “off the shelf” biomaterial for urethral repair. Urology 54(3): 407–410. Chen, F., J.J. Yoo, and A. Atala. 2000. Experimental and clinical experience using tissue regeneration for urethral reconstruction. World Journal of Urology 18(1): 67–70. Cibelli, J.B., et al. 1998. Cloned transgenic calves produced from nonquiescent fetal fibroblasts. Science 280(5367): 1256–1258. Cilento, B.G., M.R. Freeman, F.X. Schneck, A.B. Retik, and A. Atala. 1994. Phenotypic and cytogenetic characterization of human bladder urothelia expanded in vitro. Journal of Urology 152(2 Pt 2): 665–670. Colman, A., and A. Kind. 2000. Therapeutic cloning: Concepts and practicalities. Trends in Biotechnology 18(5): 192–196. Dahms, S.E., H.J. Piechota, R. Dahiya, T.F. Lue, and E.A. Tanagho. 1998. Composition and biomechanical properties of the bladder acellular matrix graft: Comparative analysis in rat, pig and human. British Journal of Urology 82(3): 411–419. De Coppi, P., et al. 2007. Isolation of amniotic stem cell lines with potential for therapy. Nature Biotechnology 25(1): 100–106. De Filippo, R.E., J.J. Yoo, and A. Atala. 2002. Urethral replacement using cell seeded tubularized collagen matrices. Journal of Urology 168(42): 1789–1792; discussion 1792–1793. De Filippo, R.E., J.J. Yoo, and A. Atala. 2003. Engineering of vaginal tissue in vivo. Tissue Engineering 9(2): 301–306. De Sousa, P.A., et al. 2002. Somatic cell nuclear transfer in the pig: Control of pronuclear formation and integration with improved methods for activation and maintenance of pregnancy. Biology of Reproduction 66(3): 642–650. De Vos, P., B. De Haan, and R. Van Schilfgaarde. 1997. Effect of the alginate composition on the biocompatibility of alginate-polylysine microcapsules. Biomaterials 18(3): 273–278. Diamond, D.A., and A.A. Caldamone. 1999. Endoscopic correction of vesicoureteral reflux in children using autologous chondrocytes: Preliminary results. Journal of Urology 162(3 Pt 2): 1185–1188. Dinnyes, A., P. De Sousa, T. King, and I. Wilmut. 2002. Somatic cell nuclear transfer: Recent progress and challenges. Cloning & Stem Cells 4(1): 81–90. El-Kassaby, A.W., A.B. Retik, J.J. Yoo, and A. Atala. 2003. Urethral stricture repair with an off-the-shelf collagen matrix. Journal of Urology 169(1): 170–173; discussion 173. Evans, M.J., C. Gurer, J.D. Loike, I. Wilmut, A.E. Schnieke, and E.A. Schon. 1999. Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep. Nature Genetics 23(1): 90–93. Fischer Lindahl, K., E. Hermel, B.E. Loveland, and C.R. Wang. 1991. Maternally transmitted antigen of mice: A model transplantation antigen. Annual Review of Immunology 9: 351–372. Fox, I.J., et al. 1998. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. New England Journal of Medicine 338(20): 1422–1426. Freeman, M.R., et al. 1997. Heparin-binding EGF-like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder. Journal of Clinical Investigation 99(5): 1028–1036. Fuchs, J.R., S. Terada, E.R. Ochoa, J.P. Vacanti, and D.O. Fauza. 2002. Fetal tissue engineering: In utero tracheal augmentation in an ovine model. Journal of Pediatric Surgery 37(7): 1000–1006. Gilbert, J.C., T. Takada, J.E. Stein, R. Langer, and J.P. Vacanti. 1993. Cell transplantation of genetically altered cells on biodegradable polymer scaffolds in syngeneic rats. Transplantation 56(2): 423–427. Gilding, D. 1981. Biodegradable polymers. In Biocompatibility of clinical implant materials, ed. D. Williams, 209–232. Boca Raton, FL: CRC Press. Gurdon, J.B. 1962a. The transplantation of nuclei between two species of Xenopus. Developmental Biology 5: 68–83. Gurdon, J.B. 1962b. The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles. Journal of Embryology & Experimental Morphology 10: 622–640. Gurdon, J.B. 1962c. Multiple genetically identical frogs. Journal of Heredity 53: 5–9. Gurdon, J.B., T.R. Elsdale, and M. Fischberg. 1958. Sexually mature individuals of Xenopus laevis from the transplantation of single somatic nuclei. Nature 182(4627): 64–65. Hadley, G.A., B. Linders, and T. Mohanakumar. 1992. Immunogenicity of MHC class I alloantigens expressed on parenchymal cells in the human kidney. Transplantation 54(3): 537–542. Harris, L.D., B.S. Kim, and D.J. Mooney. 1998. Open pore biodegradable matrices formed with gas foaming. Journal of Biomedical Materials Research 42(3): 396–402. Harriss, D.R. 1995. Smooth muscle cell culture: A new approach to the study of human detrusor physiology and pathophysiology. British Journal of Urology 75(Suppl 1): 18–26. Hiendleder, S., S.M. Schmutz, G. Erhardt, R.D. Green, and Y. Plante. 1999. Transmitochondrial differences and varying levels of heteroplasmy in nuclear transfer cloned cattle. Molecular Reproduction and Development 54(1): 24–31. Hochedlinger, K., and R. Jaenisch. 2002. Nuclear transplantation: Lessons from frogs and mice. Current Opinion in Cell Biology 14(6): 741–748. Hochedlinger, K., W.M. Rideout, M. Kyba, G.Q. Daley, R. Blelloch, and R. Jaenisch. 2004. Nuclear transplantation, embryonic stem cells and the potential for cell therapy. Hematology Journal 5(Suppl 3): 114–117. Humes, H.D., D.A. Buffington, S.M. MacKay, A.J. Funke, and W.F. Weitzel. 1999a. Replacement of renal function in uremic animals with a tissue-engineered kidney. Nature Biotechnology 17(5): 451–455. Humes, H.D., S.M. MacKay, A.J. Funke, and D.A. Buffington. 1999b. Tissue engineering of a bioartificial renal tubule assist device: In vitro transport and metabolic characteristics. Kidney International 55(6): 2502–2514. Hunter, W. 1995. Of the structure and disease of articulating cartilages. 1743. Clinical Orthopaedics & Related Research (317):3–6. Hynes, R.O. 1992. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 69(1): 11–25. Ip, T.K., P. Aebischer, and P.M. Galletti. 1988. Cellular control of membrane permeability. Implications for a bioartificial renal tubule. ASAIO Transactions 34(3): 351–355. Itskovitz-Eldor, J., et al. 2000. Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Molecular Medicine 6(2): 88–95. Jawad, H., N.N. Ali, A.R. Lyon, Q.Z. Chen, S.E. Harding, and A.R. Boccaccini. 2007. Myocardial tissue engineering: A review. Journal of Tissue Engineering and Regenerative Medicine 1: 327–342. Joki, T., et al. 2001. Continuous release of endostatin from microencapsulated engineered cells for tumor therapy. Nature Biotechnology 19(1): 35–39. Kaufman, DS., Hanson, ET., Lewis, RL., Auerbach, R., and Thomson, JA. (2001) ‘Hematopoietic colony-forming cells derived from human embryonic stem cells’. Proceedings of the National Academy of Sciences of the United States of America 98(19):10716–10721. Kaufmann, P.M., U. Kneser, H.C. Fiegel, D. Kluth, H. Herbst, and X. Rogiers. 1999. Long-term hepatocyte transplantation using three-dimensional matrices. Transplantation Proceedings 31(4): 1928–1929. Kehat, I., et al. 2001. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. Journal of Clinical Investigation 108(3): 407–414. Kershen, R.T., and A. Atala. 1999. New advances in injectable therapies for the treatment of incontinence and vesicoureteral reflux. Urologic Clinics of North America 26(1): 81–94. Kershen, R.T., J.J. Yoo, R.B. Moreland, R.J. Krane, and A. Atala. 2002. Reconstitution of human corpus cavernosum smooth muscle in vitro and in vivo. Tissue Engineering 8(3): 515–524. Kim, B.S., and D.J. Mooney. 1998. Development of biocompatible synthetic extracellular matrices for tissue engineering. Trends in Biotechnology 16(5): 224–230. Kropp, B.P., et al. 1998. Rabbit urethral regeneration using small intestinal submucosa onlay grafts. Urology 52(1): 138–142. Kwon, T.G., J.J. Yoo, and A. Atala. 2002. Autologous penile corpora cavernosa replacement using tissue engineering techniques. Journal of Urology 168(42): 1754–1758. Lanza, R.P., J.B. Cibelli, and M.D. West. 1999. Prospects for the use of nuclear transfer in human transplantation. Nature Biotechnology 17(12): 1171–1174. Lanza, R.P., J.B. Cibelli, M.D. West, E. Dorff, C. Tauer, and R.M. Green. 2001. The ethical reasons for stem cell research. Science 292(5520): 1299. Lanza, R.P., J.L. Hayes, and W.L. Chick. 1996. Encapsulated cell technology. Nature Biotechnology 14(9): 1107–1111. Lanza, R.P., et al. 2002. Generation of histocompatible tissues using nuclear transplantation. Nature Biotechnology 20(7): 689–696. Levenberg, S., J.S. Golub, M. Amit, J. Itskovitz-Eldor, and R. Langer. 2002. Endothelial cells derived from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America 99(7):4391–4396. Li, S.T. 1995. Biologic biomaterials: Tissue derived biomaterials (collagen). In The biomedical engineering handbook, ed. B. JD, 627–647. Boca Raton, FL: CRS Press. Liebert, M., et al. 1991. Stimulated urothelial cells produce cytokines and express an activated cell surface antigenic phenotype. Seminars in Urology 9(2): 124–130. Liebert, M., et al. 1997. Expression of mal is associated with urothelial differentiation in vitro: Identification by differential display reverse-transcriptase polymerase chain reaction. Differentiation 61(3): 177–185. Lim, F., and A.M. Sun. 1980. Microencapsulated islets as bioartificial endocrine pancreas. Science 210(4472): 908–910. Macchiarini, P., et al. 2008. Clinical transplantation of a tissue-engineered airway. Lancet 372(9655): 2023–2030. Machluf, M., A. Orsola, and A. Atala. 2000. Controlled release of therapeutic agents: Slow delivery and cell encapsulation. World Journal of Urology 18(1): 80–83. Machluf, M., A. Orsola, S. Boorjian, R. Kershen, and A. Atala. 2003. Microencapsulation of Leydig cells: A system for testosterone supplementation. Endocrinology 144(11): 4975–4979. MacKay, S.M., A.J. Funke, D.A. Buffington, and H.D. Humes. 1998. Tissue engineering of a bioartificial renal tubule. ASAIO Journal 44(3): 179–183. Matsumura, G., S. Miyagawa-Tomita, T. Shin’oka, Y. Ikada, and H. Kurosawa. 2003. First evidence that bone marrow cells contribute to the construction of tissue-engineered vascular autografts in vivo. Circulation 108(14): 1729–1734. Meissner, A., M. Wernig, and R. Jaenisch. 2007. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells 1. Nature Biotechnology 25(10): 1177–1181. Mikos, A.G., M.D. Lyman, L.E. Freed, and R. Langer. 1994. Wetting of poly(L-lactic acid) and poly(DL-lactic-co-glycolic acid) foams for tissue culture. Biomaterials 15(1): 55–58. Nguyen, H.T., et al. 1999. Cell-specific activation of the HB-EGF and ErbB1 genes by stretch in primary human bladder cells. In Vitro Cellular & Developmental Biology. Animal 35(7): 371–375. Nieto, J.A., J. Escandon, C. Betancor, J. Ramos, T. Canton, and V. Cuervas-Mons. 1989. Evidence that temporary complete occlusion of splenic vessels prevents massive embolization and sudden death associated with intrasplenic hepatocellular transplantation. Transplantation 47(3): 449–450. Nomi, M., A. Atala, P.D. Coppi, and S. Soker. 2002. Principals of neovascularization for tissue engineering. Molecular Aspects of Medicine 23(6): 463–483. O’Driscoll, S.W. 1998. The healing and regeneration of articular cartilage. Journal of Bone & Joint Surgery – American Volume 80(12): 1795–1812. Oberpenning, F., J. Meng, J.J. Yoo, and A. Atala. 1999. De novo reconstitution of a functional mammalian urinary bladder by tissue engineering. Nature Biotechnology 17(2): 149–155. Okita, K., T. Ichisaka, and S. Yamanaka. 2007. Generation of germline-competent induced pluripotent stem cells 1. Nature 448(7151): 313–317. Olsen, L., S. Bowald, C. Busch, J. Carlsten, and I. Eriksson. 1992. Urethral reconstruction with a new synthetic absorbable device. An experimental study. Scandinavian Journal of Urology and Nephrology 26(4): 323–326. Ott, H.C., et al. 2008. Perfusion-decellularized matrix: Using nature’s platform to engineer a bioartificial heart. Nature Medicine 14(2):213–221. Pariente, J.L., B.S. Kim, and A. Atala. 2001. In vitro biocompatibility assessment of naturally derived and synthetic biomaterials using normal human urothelial cells. Journal of Biomedical Materials Research 55(1): 33–39. Pariente, J.L., B.S. Kim, and A. Atala. 2002. In vitro biocompatibility evaluation of naturally derived and synthetic biomaterials using normal human bladder smooth muscle cells. Journal of Urology 167(4): 1867–1871. Peppas, N.A., and R. Langer. 1994. New challenges in biomaterials. Science 263(5154): 1715–1720. Piechota, H.J., S.E. Dahms, L.S. Nunes, R. Dahiya, T.F. Lue, and E.A. Tanagho. 1998. In vitro functional properties of the rat bladder regenerated by the bladder acellular matrix graft. Journal of Urology 159(5): 1717–1724. Puthenveettil, J.A., M.S. Burger, and C.A. Reznikoff. 1999. Replicative senescence in human uroepithelial cells. Advances in Experimental Medicine and Biology 462: 83–91. Raya-Rivera, A.M., C. Baez, A. Atala, and J.J. Yoo. 2008. Tissue engineered testicular prostheses with prolonged testosterone release. World Journal of Urology 26(4): 307–314. Reubinoff, B.E., M.F. Pera, C.Y. Fong, A. Trounson, and A. Bongso. 2000. Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro. Nature Biotechnology 18 (4):399–404. Reubinoff, B.E., et al. 2001. Neural progenitors from human embryonic stem cells. Nature Biotechnology 19(12): 1134–1140. Richards, M., C.Y. Fong, W.K. Chan, P.C. Wong, and A. Bongso. 2002. Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nature Biotechnology 20(9): 933–936. Rideout, W.M. 3rd, K. Eggan, and R. Jaenisch. 2001. Nuclear cloning and epigenetic reprogramming of the genome. Science 293(5532): 1093–1098. Sams, A.E., and A.J. Nixon. 1995. Chondrocyte-laden collagen scaffolds for resurfacing extensive articular cartilage defects. Osteoarthritis and Cartilage 3(1): 47–59. Santen, R., and R. Swerdloff. 1990. Clinical aspects of androgen therapy. Paper presented at the workshop conference on androgen therapy: Biologic and clinical consequences. Pennsylvania State, Philadelphia, PA. Schaefer, D., et al. 2002. Tissue-engineered composites for the repair of large osteochondral defects. Arthritis and Rheumatism 46(9): 2524–2534. Schuldiner, M., O. Yanuka, J. Itskovitz-Eldor, D.A. Melton, and N. Benvenisty. 2000. Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America 97(21):11307–11312. Schuldiner, M., et al. 2001. Induced neuronal differentiation of human embryonic stem cells. Brain Research 913(2): 201–205. Scriven, S.D., C. Booth, D.F. Thomas, L.K. Trejdosiewicz, and J. Southgate. 1997. Reconstitution of human urothelium from monolayer cultures. Journal of Urology 158(3 Pt 2): 1147–1152. Shin’oka, T., Y. Imai, and Y. Ikada. 2001. Transplantation of a tissue-engineered pulmonary artery. New England Journal of Medicine 344(7): 532–533. Shinoka, T., et al. 1995. Tissue engineering heart valves: Valve leaflet replacement study in a lamb model. Annals of Thoracic Surgery 60(6 Suppl): S513–S516. Shinoka, T., et al. 1997. Tissue-engineered heart valve leaflets: Does cell origin affect outcome? Circulation 96(9 Suppl): II-102–II-107. Shinoka, T., et al. 1998. Creation of viable pulmonary artery autografts through tissue engineering. Journal of Thoracic and Cardiovascular Surgery 115(3): 536–545; discussion 545–546. Sievert, K.D., M.E. Bakircioglu, L. Nunes, R. Tu, R. Dahiya, and E.A. Tanagho. 2000. Homologous acellular matrix graft for urethral reconstruction in the rabbit: Histological and functional evaluation. Journal of Urology 163(6): 1958–1965. Silver, F.H., and G. Pins. 1992. Cell growth on collagen: A review of tissue engineering using scaffolds containing extracellular matrix. Journal of Long-Term Effects of Medical Implants 2(1): 67–80. Smidsrod, O., and G. Skjak-Braek. 1990. Alginate as immobilization matrix for cells. Trends in Biotechnology 8(3): 71–78. Solter, D. 2000. Mammalian cloning: Advances and limitations. Nature Reviews Genetics 1(3): 199–207. Steinborn, R., et al. 2000. Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning. Nature Genetics 25(3): 255–257. Strasser, H., et al. 2004. Stem cell therapy for urinary stress incontinence. Experimental Gerontology 39(9): 1259–1265. Tai, J., H.W. Johnson, and W.J. Tze. 1989. Successful transplantation of Leydig cells in castrated inbred rats. Transplantation 47(6): 1087–1089. Tai, I.T., and A.M. Sun. 1993. Microencapsulation of recombinant cells: A new delivery system for gene therapy. FASEB Journal 7(11): 1061–1069. Takahashi, K., and S. Yamanaka. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors 2. Cell 126(4): 663–676. Takahashi, K., et al. 2007. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131(5): 861–872. Thomson, J.A., et al. 1998. Embryonic stem cell lines derived from human blastocysts. Science 282 (5391):1145–1147. van Dam, J.H., K.J. Teerds, and F.F. Rommerts. 1989. Transplantation and subsequent recovery of small amounts of isolated Leydig cells. Archives of Andrology 22(2): 123–129. Vogelstein, B., B. Alberts, and K. Shine. 2002. Genetics. Please don’t call it cloning! Science 295(5558): 1237. Wakayama, T., A.C. Perry, M. Zuccotti, K.R. Johnson, and R. Yanagimachi. 1998. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 394(6691): 369–374. Wang, T., C. Koh, and J.J. Yoo. 2003. Creation of an engineered uterus for surgical reconstruction. Paper presented at the American Academy of Pediatrics, Section on Urology, New Orleans, LA. Watanabe, M., et al. 2001. Tissue-engineered vascular autograft: Inferior vena cava replacement in a dog model. Tissue Engineering 7(4): 429–439. Wernig, M., et al. 2007. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state 1. Nature 448(7151): 318–324. Wilmut, I., A.E. Schnieke, J. McWhir, A.J. Kind, and K.H. Campbell. 1997. Viable offspring derived from fetal and adult mammalian cells. Nature 385 (6619):810–813. Yard, B.A., et al. 1993. Analysis of T cell lines from rejecting renal allografts. Kidney International – Supplement 39: S133–S138. Yiou, R., J.P. Lefaucheur, and A. Atala. 2003a. The regeneration process of the striated urethral sphincter involves activation of intrinsic satellite cells. Anatomy and Embryology 206(6): 429–435. Yiou, R., J.J. Yoo, and A. Atala. 2003b. Restoration of functional motor units in a rat model of sphincter injury by muscle precursor cell autografts. Transplantation 76(7): 1053–1060. Yokoyama, T., J. Huard, and M.B. Chancellor. 2000. Myoblast therapy for stress urinary incontinence and bladder dysfunction. World Journal of Urology 18(1): 56–61. Yoo, J.J., J. Meng, F. Oberpenning, and A. Atala. 1998. Bladder augmentation using allogenic bladder submucosa seeded with cells. Urology 51(2): 221–225. Yoo, J.J., H.J. Park, I. Lee, and A. Atala. 1999. Autologous engineered cartilage rods for penile reconstruction. Journal of Urology 162(32): 1119–1121. Yu, J., et al. 2007. Induced pluripotent stem cell lines derived from human somatic cells. Science 318(5858):1917–1920. Zhang, S.C., M. Wernig, I.D. Duncan, O. Brustle, and J.A. Thomson. 2001. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nature Biotechnology 19(12): 1129–1133. Zhou, Q., J. Brown, A. Kanarek, J. Rajagopal, and D.A. Melton. 2008. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 455(7213): 627–632.