Long-Term Effect of Outdoor Air Pollution on Mortality and Morbidity: A 12-Year Follow-Up Study for Metropolitan France

International Journal of Environmental Research and Public Health - Tập 15 Số 11 - Trang 2487
Shreosi Sanyal1,2, Thierry Rochereau3, Cara Nichole Maesano1,2, Laure Com-Ruelle3, Isabella Annesi‐Maesano1,2
1CHU Saint-Antoine [AP-HP]
2Institut Pierre Louis d'Epidémiologie et de Santé Publique
3Institut de Recherche et Documentation en Economie de la Santé

Tóm tắt

Background: Short-term effects of air pollution are documented more than long-term effects. Objective: We investigated 12-year impacts of ambient air pollutants on cardiovascular and respiratory morbidity and mortality at the departmental level in metropolitan France. Methods: Daily air pollution data at 2-km resolution, including concentrations of particulate matter of 10 µm or 2.5 µm in diameter or less (PM10 and PM2.5), nitrogen dioxide (NO2), and ozone (O3), were accrued from the CHIMERE database for 1999 and 2000. Simultaneously, morbidity (hospitalizations) and mortality data were collected in 2012 using the ESPS (Enquête Santé et Protection Sociale/Health, Health Care and Insurance Survey) survey data and the CepiDc (Centre d’Épidémiologie sur les Causes Médicales de Décès/French Epidemiology Centre on Medical Causes of Death) database. Based on Poisson regression analyses, the long-term effect was estimated. A higher risk of all-cause mortality was observed using CépiDc database, with a relative risk of 1.024 (95% CI: 1.022, 1.026) and 1.029 (95% CI: 1.027, 1.031) for a 10 µg/m3 increase in PM2.5 and PM10, respectively. Mortality due to cardiovascular and respiratory diseases likewise exhibited long-term associations with both PM2.5 and PM10. Using ESPS survey data, a significant risk was observed for both PM2.5 and PM10 in all-cause mortality and all-cause morbidity. Although a risk for higher all-cause mortality and morbidity was also present for NO2, the cause-specific relative risk due to NO2 was found to be lesser, as compared to PM. Nevertheless, cardiovascular and respiratory morbidity were related to NO2, along with PM2.5 and PM10. However, the health effect of O3 was seen to be substantially lower in comparison to the other pollutants. Conclusion: Our study confirmed that PM has a long-term impact on mortality and morbidity. Exposure to NO2 and O3 could also lead to increased health risks.

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Tài liệu tham khảo

Samek, 2016, Overall human mortality and morbidity due to exposure to air pollution, Int. J. Occup. Environ. Health, 29, 417, 10.13075/ijomeh.1896.00560

Thurston, 2016, Ambient Particulate Matter Air Pollution Exposure and Mortality in the NIH-AARP Diet and Health Cohort, Environ. Health Perspect., 124, 484, 10.1289/ehp.1509676

Cairncross, 2007, A novel air pollution index based on the relative risk of daily mortality associated with short-term exposure to common air pollutants, Atmos. Environ., 41, 8442, 10.1016/j.atmosenv.2007.07.003

Brook, 2004, Air pollution and cardiovascular disease: A statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart Association, Circulation, 109, 2655, 10.1161/01.CIR.0000128587.30041.C8

Hoek, 2001, The association between air pollution and heart failure, arrhythmia embolism, thrombosis, and other cardiovascular causes of death in a time series study, Epidemiology, 12, 355, 10.1097/00001648-200105000-00017

Peters, 2001, Increased particulate air pollution and the triggering of myocardial infarction, Circulation, 103, 2810, 10.1161/01.CIR.103.23.2810

Guo, 2018, Effect of long-term exposure to fine particulate matter on lung function decline and risk of chronic obstructive pulmonary disease in Taiwan: A longitudinal, cohort study, Lancet Planet. Health, 2, e114, 10.1016/S2542-5196(18)30028-7

Faustini, 2014, Nitrogen dioxide and mortality: Review and meta-analysis of long-term studies, Eur. Respir. J., 44, 744, 10.1183/09031936.00114713

Agius, 2014, Effects of long-term exposure to PM10 and NO2 on asthma and wheeze in a prospective birth cohort, J. Epidemiol. Community Health, 68, 21, 10.1136/jech-2013-202681

Turner, 2016, Long-Term Ozone Exposure and Mortality in a Large Prospective Study, Am. J. Respir. Crit. Care Med., 193, 1134, 10.1164/rccm.201508-1633OC

Beelen, 2014, Effects of long-term exposure to air pollution on natural-cause mortality: An analysis of 22 European cohorts within the multicenter ESCAPE project, Lancet, 383, 785, 10.1016/S0140-6736(13)62158-3

Cesaroni, 2013, Long-term exposure to urban air pollution and mortality in a cohort of more than a million adults in Rome, Environ. Health Perspect., 121, 324, 10.1289/ehp.1205862

Pascal, 2016, The mortality impacts of fine particles in France, Sci. Total Environ., 571, 416, 10.1016/j.scitotenv.2016.06.213

Kunzli, 2000, Public-health impact of outdoor and traffic-related air pollution: A European assessment, Lancet, 356, 795, 10.1016/S0140-6736(00)02653-2

Menut, 2013, CHIMERE 2013: A model for regional atmospheric composition modelling, Geosci. Model Dev., 6, 981, 10.5194/gmd-6-981-2013

Grant, 2009, Air Pollution in relation to U.S. cancer mortality rates: An ecological study; Likely role of carbonaceous aerosols and polycyclic aromatic hydrocarbons, Anticancer Res., 29, 3537

Hansell, 2013, Aircraft noise and cardiovascular disease near Heathrow airport in London: Small area study, Br. Med. J., 347, f5432, 10.1136/bmj.f5432

Rue, 2009, Approximate Bayesian inference for the latent Gaussian models using integrated nested Laplace approximations, J. R. Stat. Soc., 71, 319, 10.1111/j.1467-9868.2008.00700.x

Besag, 1991, Bayesian image restoration, with two applications in spatial statistics, Ann. Inst. Stat. Math., 43, 1, 10.1007/BF00116466

Lee, 2014, A Bayesian localized conditional autoregressive model for estimating the health effects of air pollution, Biometrics, 70, 419, 10.1111/biom.12156

Rey, G., Jougla, E., Fouillet, A., and Hémon, D. (2009). Ecological association between a deprivation index and mortality in France over the period 1997-2001: Variations with spatial scale, degree of urbanicity, age, gender and cause of death. BMC Public Health, 9.

Eftim, 2008, Fine particulate matter and mortality: A comparison of the six cities and American cancer society cohorts with a Medicare cohort, Epidemiology, 19, 209, 10.1097/EDE.0b013e3181632c09

Latza, 2009, Effects of nitrogen dioxide on human health: Systematic review of experimental and epidemiological studies conducted between 2002 and 2006, Int. J. Hyg. Environ. Health, 212, 271, 10.1016/j.ijheh.2008.06.003

Chen, 2018, OP VII-2 Does temperature confounding control influence the modifying effect of air temperature in ozone-mortality associations?, Occup. Environ. Med., 75, A14

Guerreiro, 2014, Air quality status and trends in Europe, Atmos. Environ., 98, 376, 10.1016/j.atmosenv.2014.09.017

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International Journal of Environmental Research and Public Health

Tập 15 Số 11

2487

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