The impact of the Alzheimer's Disease Neuroimaging Initiative 2: What role do public‐private partnerships have in pushing the boundaries of clinical and basic science research on Alzheimer's disease?

Alzheimer's & Dementia - Tập 11 - Trang 860-864 - 2015
Dorothy M. Jones-Davis1, Neil Buckholtz2
1Foundation for the National Institutes of Health, Bethesda, MD, USA
2National Institute on Aging, National Institutes of Health, Bethesda, MD, USA

Tóm tắt

AbstractIn the growing landscape of biomedical public‐private‐partnerships, particularly for Alzheimer's disease, the question is posed as to their value. What impacts do public‐private‐partnerships have on clinical and basic science research in Alzheimer's disease? The authors answer the question using the Alzheimer's Disease Neuroimaging Initiative (ADNI) as a test case and example. ADNI is an exemplar of how public‐private‐partnerships can make an impact not only on clinical and basic science research and practice (including clinical trials), but also of how similar partnerships using ADNI as an example, can be designed to create a maximal impact within their fields.

Tài liệu tham khảo

10.1007/s11948-010-9239-x 10.1177/0306312705052359 Thomson Reuters on behalf of IMI Programme Office. Bibliometric analysis of ongoing projects: innovative medicines initiative joint undertaking (Fifth Report: December 2014). Available at:http://www.imi.europa.eu/sites/default/files/uploads/documents/BibliometricsReport5.pdf. Accessed February 27 2015. Freire MC, 2014, Partnerships: beyond the buzzword, Sci Transl Med, 6, 242ed15, 10.1126/scitranslmed.3009673 Lim MD, 2014, Consortium Sandbox: building and sharing resources, Sci Transl Med, 6, 242cm6 Consortiapedia: a FasterCures Project. Available at:http://consortiapedia.fastercures.org/. Accessed April 23 2015. Alzheimer's Association. 2014 Alzheimer's disease facts and figures, 2014, Alzheimers Dement, 10, e47 10.1016/j.jalz.2013.05.1761 10.1016/j.jalz.2014.06.014 10.1016/j.jalz.2011.03.004 10.1016/j.jalz.2011.03.003 10.1016/j.jalz.2011.03.008 10.1016/j.jalz.2011.03.005 ADNI Data Usage Stats. Available at:http://adni.loni.usc.edu/data‐samples/adni‐data‐usage‐stats/. Accessed February 27 2015. SchmidtME ChiaoP KleinG MatthewsD ThurfjellL ColePE et al.The influence of biological and technical factors on quantitative analysis of amyloid PET: points to consider and recommendations for controlling variability in longitudinal data.Alzheimers Dement201410.1016/j.jalz.2014.09.004[Epub ahead of print] 10.1007/s11682-012-9186-z 10.1038/nrd4439 2012, Worldwide Alzheimer's Disease Neuroimaging Initiative, Alzheimers Dement, 8, 337, 10.1016/j.jalz.2012.04.007 10.1016/j.pneurobio.2011.09.005 10.1016/S1474-4422(11)70263-0 10.1089/neu.2014.3384 2013 Geoffrey Beene Global NeuroDiscovery Challenge. Available at:http://geoffreybeenechallenge.org/mind‐the‐data/. Accessed February 27 2015. Global CEO Initiative.Big Data Challenge for Alzheimer's Disease Launches in Global Effort to Use Innovative Open Science Techniques to Improve Diagnosis and Treatment. Available at:http://www.ceoalzheimersinitiative.org/big‐data‐challenge‐alzheimer%E2%80%99s‐disease‐launches‐global‐effort‐use‐innovative‐open‐science‐techniques. Accessed February 27 2015. Coalition Against Major Diseases. Alzheimer's Disease Clinical Trial Simulation Tool. Available at:http://c‐path.org/programs/camd/simulation‐tool/. Accessed February 27 2015. 10.1002/cpt.16 US Department of Health and Human Services. National Plan to Address Alzheimer's Disease: 2014 Update. Available at:http://aspe.hhs.gov/daltcp/napa/NatlPlan2014.pdf. Accessed February 27 2015.
Thông tin
Thông tin xuất bản

Alzheimer's & Dementia

Tập 11

860-864

Thông tin tác giả