Preparation of prunin with the help of immobilized naringinase pretreated with alkaline buffer

Applied Biochemistry and Biotechnology - Tập 9 - Trang 483-488 - 1984
M. RoitNer1, Th. Schalkhammer1, F. Pittner1
1Ludwig Boltzmann Forschungsstelle für Biochemie, Institut für Algemeine Biochemie der Universität Wien, Wien, Austria

Tóm tắt

Immobilized naringinase can be converted to a preparation showing only rhamnosidase activity by treatment with 0.1M glycine-NaOH buffer, pH 12. A simple method is described to obtain pure prunin in high yield from naringin with the help of this immobilizate.

Tài liệu tham khảo

Roshchin, Yu. V., and Gerashchenko, G. I. (1973),Vopr. Farm. Dal’nem Vostoke 1, 134. Heraud, G., and Roux, E. (1974),Diabete 22 (1), 19. Fox, D. W., Savage, W. L., and Wender, S. H. (1952),J. Am. Chem. Soc. 75, 2504. Bognar, R., Tokes, A. L., and Frenzel, H. (1969),Acta Chim. (Budapest) (1969)61 (1), 79. Habelt, K., and Pittner, F. (1983),Anal. Biochem. 134, 395. Le Rosen, A. L., Moravek, R. T., and Carlton, J. K. (1952),Anal. Chem. 24, 1335. Tyihak, E., Vaguifalvi, D., and Hagony, P. L. (1963),J. Chromatogr. 11, 45. Anfarbereagentien fur Dunnschicht- und Papierchromatographie (1970), E. Merck, Darmstadt. Jacobs, S. (1959),Nature 183, 262. Weetall, H. (1976), inMeth. Enzymol. 44 (Mosbach, K., ed.) p. 139, Academic Press, New York. Pittner, F., Miron, T., Pittner, G., and Wilchek, M. (1980),J. Solid-Phase Biochem. 5, 167. Cuatrecasas, P. (1970),J. Biol. Chem. 245, 3059. The Merck Index (1968), 8th edition, Stecker, P. G., ed., Merck, Rahway, New Jersey, p. 720.