Genome-wide DNA demethylation in mammals

Genome Biology - Tập 11 - Trang 1-4 - 2010
Lionel A Sanz1, Satya K Kota1, Robert Feil1
1Institute of Molecular Genetics, CNRS UMR-5535 and University of Montpellier, Montpellier, France

Tóm tắt

The cytidine deaminase AID and elongator-complex proteins contribute to the extensive removal of DNA methylation in mammalian primordial germ cells and in the paternal pronucleus of the zygote.

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