Rhen, 2005, Antiinflammatory action of glucocorticoids—new mechanisms for old drugs, N Engl J Med, 353, 1711, 10.1056/NEJMra050541
Thiele, 2005, Current use of glucocorticoids in patients with rheumatoid arthritis in Germany, Arthritis Rheum, 53, 740, 10.1002/art.21467
Walsh, 1996, Use of oral corticosteroids in the community and the prevention of secondary osteoporosis: a cross sectional study, BMJ, 313, 344, 10.1136/bmj.313.7053.344
Buttgereit, 2004, Glucocorticoids in the treatment of rheumatic diseases: an update on the mechanisms of action, Arthritis Rheum, 50, 3408, 10.1002/art.20583
Metge, 2001, Use of pharmaceuticals by inflammatory bowel disease patients: a population-based study, Am J Gastroenterol, 96, 3348, 10.1111/j.1572-0241.2001.05255.x
Heijdra, 2007, Inhaled corticosteroids in patients with COPD: maintain current guidelines, Ned Tijdschr Geneeskd, 151, 2195
Highland, 2004, Inhaled corticosteroids in chronic obstructive pulmonary disease: is there a long-term benefit?, Curr Opin Pulm Med, 10, 113, 10.1097/00063198-200403000-00005
Song, 2005, New glucocorticoids on the horizon: repress, don’t activate!, J Rheumatol, 32, 1199
Pratt, 2006, Chaperoning of glucocorticoid receptors, Handb Exp Pharmacol, 111, 10.1007/3-540-29717-0_5
De Bosscher, 2003, The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression, Endocr Rev, 24, 488, 10.1210/er.2002-0006
Nissen, 2000, The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain, Genes Dev, 14, 2314, 10.1101/gad.827900
Adcock, 2001, Cross-talk between pro-inflammatory transcription factors and glucocorticoids, Immunol Cell Biol, 79, 376, 10.1046/j.1440-1711.2001.01025.x
Hayashi, 2004, Effects of glucocorticoids on gene transcription, Eur J Pharmacol, 500, 51, 10.1016/j.ejphar.2004.07.011
Ehrchen, 2007, Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes, Blood, 109, 1265, 10.1182/blood-2006-02-001115
Catley, 2007, Dissociated steroids, Sci World J, 7, 421, 10.1100/tsw.2007.97
Schacke, 2002, Mechanisms involved in the side effects of glucocorticoids, Pharmacol Ther, 96, 23, 10.1016/S0163-7258(02)00297-8
Schacke, 2004, Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects, Proc Natl Acad Sci U S A, 101, 227, 10.1073/pnas.0300372101
Stahn, 2007, Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists, Mol Cell Endocrinol, 275, 71, 10.1016/j.mce.2007.05.019
McMaster, 2007, Modelling the glucocorticoid receptor and producing therapeutic agents with anti-inflammatory effects but reduced side-effects, Exp Physiol, 92, 299, 10.1113/expphysiol.2006.036194
Lin, 2002, trans-Activation and repression properties of the novel nonsteroid glucocorticoid receptor ligand 2,5-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5-(1-methylcyclohexen-3-y1)-1H-[1]benzopyrano[3,4-f]quinoline (A276575) and its four stereoisomers, Mol Pharmacol, 62, 297, 10.1124/mol.62.2.297
Coghlan, 2003, A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effects, Mol Endocrinol, 17, 860, 10.1210/me.2002-0355
De Bosscher, 2005, A fully dissociated compound of plant origin for inflammatory gene repression, Proc Natl Acad Sci U S A, 102, 15827, 10.1073/pnas.0505554102
Galon, 2002, Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells, FASEB J, 16, 61, 10.1096/fj.01-0245com
Losel, 2003, Nongenomic actions of steroid hormones, Nat Rev Mol Cell Biol, 4, 46, 10.1038/nrm1009
Buttgereit, 2002, Rapid glucocorticoid effects on immune cells, Steroids, 67, 529, 10.1016/S0039-128X(01)00171-4
Stellato, 2004, Post-transcriptional and nongenomic effects of glucocorticoids, Proc Am Thorac Soc, 1, 255, 10.1513/pats.200402-015MS
Solito, 2003, Endocrinology, 144, 1164, 10.1210/en.2002-220592
Qiu, 2003, Nongenomic mechanism of glucocorticoid inhibition of bradykinin-induced calcium influx in PC12 cells: possible involvement of protein kinase C, Life Sci, 72, 2533, 10.1016/S0024-3205(03)00168-1
Long, 2005, Rapid nongenomic inhibitory effects of glucocorticoids on phagocytosis and superoxide anion production by macrophages, Steroids, 70, 55, 10.1016/j.steroids.2004.10.004
Liu, 2005, Rapid non-genomic inhibitory effects of glucocorticoids on human neutrophil degranulation, Inflamm Res, 54, 37, 10.1007/s00011-004-1320-y
Koukouritaki, 1999, Tyrosine phosphorylation of focal adhesion kinase and paxillin regulates the signaling mechanism of the rapid nongenomic action of dexamethasone on actin cytoskeleton, Mol Med, 5, 731, 10.1007/BF03402097
Song, 2006, Non-genomic glucocorticoid effects to provide the basis for new drug developments, Mol Cell Endocrinol, 246, 142, 10.1016/j.mce.2005.11.012
Tillmann, 2004, Delayed genomic and acute nongenomic action of glucocorticosteroids in seasonal allergic rhinitis, Eur J Clin Invest, 34, 67, 10.1111/j.1365-2362.2004.01293.x
Jacobs, 2001, Short term effects of corticosteroid pulse treatment on disease activity and the well being of patients with active rheumatoid arthritis, Ann Rheum Dis, 60, 61, 10.1136/ard.60.1.61
Youssef, 1997, Effects of pulse methylprednisolone on inflammatory mediators in peripheral blood, synovial fluid, and synovial membrane in rheumatoid arthritis, Arthritis Rheum, 40, 1400, 10.1002/art.1780400807
Gametchu, 1993, Use of receptor antibodies to demonstrate membrane glucocorticoid receptor in cells from human leukemic patients, FASEB J, 7, 1283, 10.1096/fasebj.7.13.8405814
Gametchu, 2002, Correlation of membrane glucocorticoid receptor levels with glucocorticoid-induced apoptotic competence using mutant leukemic and lymphoma cells lines, J Cell Biochem, 87, 133, 10.1002/jcb.10288
Bartholome, 2004, Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis, FASEB J, 18, 70, 10.1096/fj.03-0328com
Cole, 2006, Glucocorticoid action and the development of selective glucocorticoid receptor ligands, Biotechnol Annu Rev, 12, 269, 10.1016/S1387-2656(06)12008-6
Lowenberg, 2005, Rapid immunosuppressive effects of glucocorticoids mediated through Lck and Fyn, Blood, 106, 1703, 10.1182/blood-2004-12-4790
Lowenberg, 2006, Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN, EMBO Rep, 7, 1023, 10.1038/sj.embor.7400775
Zamoyska, 2003, The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation, Immunol Rev, 191, 107, 10.1034/j.1600-065X.2003.00015.x
Lowenberg, 2007, Glucocorticoid signaling: a nongenomic mechanism for T-cell immunosuppression, Trends Mol Med, 13, 158, 10.1016/j.molmed.2007.02.001