Integration of a CD19 CAR into the TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells

Molecular Therapy - Tập 25 - Trang 949-961 - 2017
Daniel T. MacLeod1, Jeyaraj Antony1, Aaron J. Martin1, Rachel J. Moser2,3, Armin Hekele1, Keith J. Wetzel1, Audrey E. Brown1, Melissa A. Triggiano1, Jo Ann Hux1, Christina D. Pham1, Victor V. Bartsevich1, Caitlin A. Turner1, Janel Lape1, Samantha Kirkland1, Clayton W. Beard1, Jeff Smith1, Matthew L. Hirsch2,3, Michael G. Nicholson1, Derek Jantz1, Bruce McCreedy1
1Precision BioSciences, Durham, NC 27701, USA
2Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
3Department of Ophthalmology, University of North Carolina, Chapel Hill, NC 27599, USA

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