Automatic annotation of organellar genomes with DOGMA

Bioinformatics - Tập 20 Số 17 - Trang 3252-3255 - 2004
Stacia K. Wyman1, Robert K. Jansen2, Jeffrey L. Boore3
1Department of Computer Sciences#TAB#
2Section of Integrative Biology, Institute of Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA#TAB#
3DOE Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA#TAB#

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Abstract Summary: The Dual Organellar GenoMe Annotator (DOGMA) automates the annotation of organellar (plant chloroplast and animal mitochondrial) genomes. It is a Web-based package that allows the use of BLAST searches against a custom database, and conservation of basepairing in the secondary structure of animal mitochondrial tRNAs to identify and annotate genes. DOGMA provides a graphical user interface for viewing and editing annotations. Annotations are stored on our password-protected server to enable repeated sessions of working on the same genome. Finished annotations can be extracted for direct submission to GenBank. Availability:  http://phylocluster.biosci.utexas.edu/dogma/ Supplementary information: Detailed documentation and tutorials for annotating both animal mitochondrial and plant chloroplast genomes can be found on the DOGMA home page.

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Bioinformatics

Tập 20 Số 17

3252-3255

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