EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis

Annals of the Rheumatic Diseases - Tập 69 Số 2 - Trang 325-331 - 2010
M.J. Peters1, Deborah Symmons2, David McCarey3, B. A. C. Dijkmans4,1, Paulo Nicola5, Tore K Kvien6, Iain B. McInnes7, H Haentzschel8, Miguel Á. González‐Gay9, Sella Aarrestad Provan6, Anne Grete Semb6, Prodromos Sidiropoulos10, George D. Kitas11, Yvo M. Smulders12, Martin Soubrier13, Zoltán Szekanecz14, Naveed Sattar15, Michael T. Nurmohamed4,1,13
1Department of Rheumatology, VU University Medical Centre, Amsterdam, The Netherlands
2University of Manchester, Manchester, UK
3Glasgow Royal Infirmary, Glasgow, UK
4Department of Rheumatology, Jan van Breemen Institute, Amsterdam, The Netherlands
5Department of Preventive Medicine, Faculty of Medicine of Lisbon, Lisbon, Portugal
6Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
7Centre for Rheumatic Diseases, University of Glasgow, UK
8Rheumazentrum am Universitätsklinikum Leipzig, Leipzig, Germany
9Rheumatology, Hospital Xeral-Calde, Lugo, Spain
10Department of Rheumatology, Clinical Immunology and Allergy, University of Crete Medical School, Heraklion, Greece
11Dudley Group of Hospitals NHS Trust Russells Hall Hospital, Dudley, UK
12Department of Internal Medicine, VU University Medical Centre, Amsterdam, the Netherlands
13Hôpital Gabriel Montpied, Service de Rhumatologie, Clermont-Ferrand, France
14Department of Rheumatology, University of Debrecen, Debrecen, Hungary
15BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK

Tóm tắt

Objectives:To develop evidence-based EULAR recommendations for cardiovascular (CV) risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA).Methods:A multidisciplinary expert committee was convened as a task force of the EULAR Standing Committee for Clinical Affairs (ESCCA), comprising 18 members including rheumatologists, cardiologists, internists and epidemiologists, representing nine European countries. Problem areas and related keywords for systematic literature research were identified. A systematic literature research was performed using MedLine, Embase and the Cochrane library through to May 2008. Based on this literature review and in accordance with the EULAR’s “standardised operating procedures”, the multidisciplinary steering committee formulated evidence-based and expert opinion-based recommendations for CV risk screening and management in patients with inflammatory arthritis.Results:Annual CV risk assessment using national guidelines is recommended for all patients with RA and should be considered for all patients with AS and PsA. Any CV risk factors identified should be managed according to local guidelines. If no local guidelines are available, CV risk management should be carried out according to the SCORE function. In addition to appropriate CV risk management, aggressive suppression of the inflammatory process is recommended to further lower the CV risk.Conclusions:Ten recommendations were made for CV risk management in patients with RA, AS and PsA. The strength of the recommendations differed between RA on the one hand, and AS and PsA, on the other, as evidence for an increased CV risk is most compelling for RA.

Từ khóa


Tài liệu tham khảo

Thông tin
Thông tin xuất bản

Annals of the Rheumatic Diseases

Tập 69 Số 2

325-331

Thông tin tác giả