Specific Reading Disability: Identification of an Inherited Form Through Linkage Analysis

American Association for the Advancement of Science (AAAS) - Tập 219 Số 4590 - Trang 1345-1347 - 1983
Shelley D. Smith1,2, William J. Kimberling1,3, Bruce F. Pennington4, Herbert A. Lubs5
1Boys Town Institute for Communication Disorders, Omaha, Nebraska 68131
2Center for the Molecular Biology of Neurosensory Systems
3Center for Sensory Neuroscience
4Department of Psychiatry, University of Colorado Health Sciences Center, Denver 80262
5Mailman Center for Child Development, University of Miami, Miami, Florida 33101

Tóm tắt

Linkage analysis in families with apparent autosomal dominant reading disability produced a lod score of 3.241. Since the traditionally accepted significance level for linkage is a lod score of 3.0, these results strongly suggest that a gene playing a major etiologic role in one form of reading disability is on chromosome 15.

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Tài liệu tham khảo

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American Association for the Advancement of Science (AAAS)

Tập 219 Số 4590

1345-1347

Thông tin tác giả