High-resolution ultrasonography and 3.0 T magnetic resonance imaging in erosive and nodal hand osteoarthritis: high frequency of erosions in nodal osteoarthritis

Clinical Rheumatology - Tập 32 - Trang 755-762 - 2013
Marianna Vlychou1, Athanasios Koutroumpas2, Ioannis Alexiou2, Ioannis Fezoulidis1, Lazaros I. Sakkas2,3
1Department of Radiology, Thessaly University School of Medicine, Larissa, Greece
2Rheumatology Clinic, University General Hospital of Larissa, Larissa, Greece
3Center for Molecular Medicine, Old Dominion University, Norfolk, USA

Tóm tắt

Erosive osteoarthritis (EOA) is defined as hand osteoarthritis (OA) with interphalangeal joint erosions on plain radiographs. We sought to find ultrasound (US) and magnetic resonance imaging (MRI) features that could distinguish EOA from nodal hand OA (NOA). Symptomatic consecutive patients with hand OA as defined by the American College of Rheumatology criteria (13 EOA patients as defined by erosion in ≥1 interphalangeal joint and seven nodal OA patients) and five normal individuals were examined by plain radiography, US, and MRI. Patients and controls underwent evaluation of metacarpophalangeal and interphalangeal joints by US, and all fingers from second to fifth digit by MRI. A total of 240 joints in symptomatic patients were examined by both imaging modalities. Synovitis, osteophytes, cartilage loss, and erosions were frequently detected in the joints of patients with EOA and NOA. Six of seven patients with NOA had joint erosions that were seen on MRI or US scan but seen on plain radiographs. The overall concordance between MRI and US findings was substantial for osteophytes (κ = 0.79) and excellent for cysts (κ = 0.85), erosions (κ = 0.84), synovitis (κ = 0.82), and tenosynovitis (κ = 0.83) in both groups. Inflammatory changes, such as effusions and synovitis, and structural changes, such as erosions, were frequently detected by US and MRI in EOA and nodal OA. These findings may support the hypothesis that EOA could not be a separate entity but may represent the severe end of the spectrum of hand OA.

Tài liệu tham khảo

Martel W, Stuck KJ, Dworin AM, Hylland RG (1980) Erosive osteoarthritis and psoriatic arthritis: a radiologic comparison in the hand, wrist, and foot. AJR Am J Roentgenol 134:125–135 Punzi L, Ramonda R, Sfriso P (2004) Erosive osteoarthritis. Best Pract Res Clin Rheumatol 18:739–758 Tan AL, Grainger AJ, Tanner SF, Shelley DM, Pease C, Emery P, McGonagle D (2005) High-resolution magnetic resonance imaging for the assessment of hand osteoarthritis. Arthritis Rheum 52:2355–2365 Wittoek R, Carron P, Verbruggen G (2010) Structural and inflammatory sonographic findings in erosive and non-erosive osteoarthritis of the interphalangeal finger joints. Ann Rheum Dis 69:2173–2176 Haugen IK, Lillegraven S, Slatkowsky-Christensen B, Haavardsholm EA, Sesseng S, Kvien TK, van der Heijde D, Boyesen P (2011) Hand osteoarthritis and MRI: development and first validation step of the proposed Oslo Hand Osteoarthritis MRI score. Ann Rheum Dis 70:1033–1038 Vlychou M, Koutroumpas A, Malizos K, Sakkas LI (2009) Ultrasonographic evidence of inflammation is frequent in hands of patients with erosive osteoarthritis. Osteoarthr Cartil 17:1283–1287 Iagnocco A, Filippucci E, Ossandon A, Ciapetti A, Salaffi F, Basili S, Grassi W, Valesini G (2005) High resolution ultrasonography in detection of bone erosions in patients with hand osteoarthritis. J Rheumatol 32:2381–2383 Koutroumpas AC, Alexiou IS, Vlychou M, Sakkas LI (2010) Comparison between clinical and ultrasonographic assessment in patients with erosive osteoarthritis of the hands. Clin Rheumatol 29:511–516 Felson DT, Gale DR, Elon Gale M, Niu J, Hunter DJ, Goggins J, Lavalley MP (2005) Osteophytes and progression of knee osteoarthritis. Rheumatology (Oxford) 44:100–104 Altman R, Alarcon G, Appelrouth D, Bloch D, Borenstein D, Brandt K, Brown C, Cooke TD, Daniel W, Gray R et al (1990) The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand. Arthritis Rheum 33:1601–1610 McNally EG (2008) Ultrasound of the small joints of the hands and feet: current status. Skeletal Radiol 37:99–113 Zhang W, Doherty M, Leeb BF, Alekseeva L, Arden NK, Bijlsma JW, Dincer F, Dziedzic K, Hauselmann HJ, Kaklamanis P, Kloppenburg M, Lohmander LS, Maheu E, Martin-Mola E, Pavelka K, Punzi L, Reiter S, Smolen J, Verbruggen G, Watt I, Zimmermann-Gorska I (2009) EULAR evidence-based recommendations for the diagnosis of hand osteoarthritis: report of a task force of ESCISIT. Ann Rheum Dis 68:8–17 Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174 Schraml C, Schwenzer NF, Martirosian P, Koetter I, Henes JC, Geiger K, Claussen CD, Horger M (2011) Assessment of synovitis in erosive osteoarthritis of the hand using DCE-MRI and comparison with that in its major mimic, the psoriatic arthritis. Acad Radiol 18:804–809 Grainger AJ, Farrant JM, O'Connor PJ, Tan AL, Tanner S, Emery P, McGonagle D (2007) MR imaging of erosions in interphalangeal joint osteoarthritis: is all osteoarthritis erosive? Skeletal Radiol 36:737–745 Kwok WY, Kloppenburg M, Rosendaal FR, van Meurs JB, Hofman A, Bierma-Zeinstra SM (2011) Erosive hand osteoarthritis: its prevalence and clinical impact in the general population and symptomatic hand osteoarthritis. Ann Rheum Dis 70:1238–1242 Haugen IK, Boyesen P, Slatkowsky-Christensen B, Sesseng S, Bijsterbosch J, van der Heijde D, Kvien TK (2012) Comparison of features by MRI and radiographs of the interphalangeal finger joints in patients with hand osteoarthritis. Ann Rheum Dis 71:345–350 Haugen IK, Boyesen P (2011) Imaging modalities in hand osteoarthritis—status and perspectives of conventional radiography, magnetic resonance imaging, and ultrasonography. Arthritis Res Ther 13:248 Keen HI, Wakefield RJ, Grainger AJ, Hensor EM, Emery P, Conaghan PG (2008) An ultrasonographic study of osteoarthritis of the hand: synovitis and its relationship to structural pathology and symptoms. Arthritis Rheum 59:1756–1763 Crema MD, Roemer FW, Zhu Y, Marra MD, Niu J, Zhang Y, Lynch JA, Javaid MK, Lewis CE, El-Khoury GY, Felson DT, Guermazi A (2010) Subchondral cystlike lesions develop longitudinally in areas of bone marrow edema-like lesions in patients with or at risk for knee osteoarthritis: detection with MR imaging—the MOST study. Radiology 256:855–862 Tehranzadeh J, Ashikyan O, Anavim A, Shin J (2008) Detailed analysis of contrast-enhanced MRI of hands and wrists in patients with psoriatic arthritis. Skeletal Radiol 37:433–442 Walther M, Harms H, Krenn V, Radke S, Kirschner S, Gohlke F (2002) Synovial tissue of the hip at power Doppler US: correlation between vascularity and power Doppler US signal. Radiology 225:225–231 McCune WJ, Dedrick DK, Aisen AM, MacGuire A (1990) Sonographic evaluation of osteoarthritic femoral condylar cartilage. Correlation with operative findings. Clin Orthop Relat Res, (254):230–235 Walther M, Harms H, Krenn V, Radke S, Faehndrich TP, Gohlke F (2001) Correlation of power Doppler sonography with vascularity of the synovial tissue of the knee joint in patients with osteoarthritis and rheumatoid arthritis. Arthritis Rheum 44:331–338 Keen HI, Wakefield RJ, Grainger AJ, Hensor EM, Emery P, Conaghan PG (2008) Can ultrasonography improve on radiographic assessment in osteoarthritis of the hands? A comparison between radiographic and ultrasonographic detected pathology. Ann Rheum Dis 67:1116–1120 Loeuille D, Sauliere N, Champigneulle J, Rat AC, Blum A, Chary-Valckenaere I (2011) Comparing non-enhanced and enhanced sequences in the assessment of effusion and synovitis in knee OA: associations with clinical, macroscopic and microscopic features. Osteoarthr Cartil 19:1433–1439 Saadat E, Jobke B, Chu B, Lu Y, Cheng J, Li X, Ries MD, Majumdar S, Link TM (2008) Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference. Eur Radiol 18:2292–2302 Zanetti M, Bruder E, Romero J, Hodler J (2000) Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings. Radiology 215:835–840 Leydet-Quilici H, Le Corroller T, Bouvier C, Giorgi R, Argenson JN, Champsaur P, Pham T, de Paula AM, Lafforgue P (2010) Advanced hip osteoarthritis: magnetic resonance imaging aspects and histopathology correlations. Osteoarthr Cartil 18:1429–1435 Haugen IK, Boyesen P, Slatkowsky-Christensen B, Sesseng S, van der Heijde D, Kvien TK (2012) Associations between MRI-defined synovitis, bone marrow lesions and structural features and measures of pain and physical function in hand osteoarthritis. Ann Rheum Dis 71:899–904