Temporal relationships in the effects of protein‐free diet on the activities of rat liver branched‐chain ketoacid dehydrogenase complex and kinase

FEBS Letters - Tập 215 - Trang 13-15 - 1987
M. Beggs1, H. Patel1, J. Espinal1, P.J. Randle1
1Nuffield Department of Clinical Biochemistry, John Radcliffe Hospital, Oxford OX3 9DU, England

Tóm tắt

Feeding rats 0% casein diet decreased liver activities of branched‐chain ketoacid dehydrogenase complex (active form) and of activator protein (complete within 4 days), and increased activity of branched‐chain ketoacid dehydrogenase kinase (complete within 9–10 days). Refeeding normal diet to rats fed 0% casein diet for 10 days resulted in a rapid and partial (approx. 50%) reversal of the above effects within 24 h; complete reversal required 20–30 days of refeeding.

Tài liệu tham khảo

1987 P.J. Randle P.A. Patston J. Espinal P. Boyer E.G. Krebs The Enzymes 97 121 10.1016/0014-5793(84)80868-6 10.1042/bj2250509 10.1016/S0006-291X(83)80119-3 10.1042/bj2220711 10.1042/bj2350429 10.1042/bj2370285
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FEBS Letters

Tập 215

13-15

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