Production and neuroprotective functions of fractalkine in the central nervous system

Bazan, 1997, A new class of membrane-bound chemokine with a CX3C motif, Nature, 385, 640, 10.1038/385640a0 Boehme, 2000, The chemokine fractalkine inhibits Fas-mediated cell death of brain microglia, J. Immunol., 165, 397, 10.4049/jimmunol.165.1.397 Combs, 2001, Beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis, J. Neurosci., 21, 1179, 10.1523/JNEUROSCI.21-04-01179.2001 Fraticelli, 2002, Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses, J. Clin. Invest., 107, 1173, 10.1172/JCI11517 Harrison, 1998, Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia, Proc. Natl. Acad. Sci. USA, 95, 10896, 10.1073/pnas.95.18.10896 Hatori, 2002, Fractalkine and fractalkine receptors in human neurons and glial cells, J. Neurosci. Res., 69, 418, 10.1002/jnr.10304 Hughes, 2002, Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS, Glia., 37, 314, 10.1002/glia.10037 Meda, 1995, Activation of microglial cells by beta-amyloid protein and interferon-gamma, Nature., 374, 647, 10.1038/374647a0 Meucci, 2000, Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival, Proc. Natl. Acad. Sci. USA, 97, 8075, 10.1073/pnas.090017497 Pereira, 2001, Enhanced expression of fractalkine in HIV-1 associated dementia, J. Neuroimmunol., 115, 168, 10.1016/S0165-5728(01)00262-4 Selmaj, 1991, Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin, J. Immunol., 147, 1522, 10.4049/jimmunol.147.5.1522 Suzumura, 1999, Ibudilast suppresses TNFalpha production by glial cells functioning mainly as type III phosphodiesterase inhibitor in the CNS, Brain Res., 837, 203, 10.1016/S0006-8993(99)01666-2 Suzumura, 1987, MHC antigen expression on bulk isolated macrophage-microglia from newborn mouse brain: induction of Ia antigen expression by gamma-interferon, J. Neuroimmunol., 15, 263, 10.1016/0165-5728(87)90121-4 Tanaka, 1994, Detection of superoxide production by activated microglia using a sensitive and specific chemiluminescence assay and microglia-mediated PC12h cell death, J. Neurochem., 63, 266, 10.1046/j.1471-4159.1994.63010266.x Tarozzo, 2002, Expression of fractalkine and its receptor, CX3CR1, in response to ischaemia-reperfusion brain injury in the rat, Eur. J. Neurosci., 15, 1663, 10.1046/j.1460-9568.2002.02007.x Tong, 2000, Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system, J. Immunol., 164, 1333, 10.4049/jimmunol.164.3.1333 Umehara, 2001, Fractalkine and vascular injury, Trends Immunol., 22, 602, 10.1016/S1471-4906(01)02051-8 Wood, 1995, Microglia as a unique cellular target in the treatment of stroke: potential neurotoxic mediators produced by activated microglia, Neurol. Res., 17, 242, 10.1080/01616412.1995.11740321 Xie, 2002, Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia, J. Neurosci., 22, 3484, 10.1523/JNEUROSCI.22-09-03484.2002 Yoshida, 2001, Synergistic stimulation, by tumor necrosis factor-alpha and interferon-gamma, of fractalkine expression in human astrocytes, Neurosci. Lett., 303, 132, 10.1016/S0304-3940(01)01699-8 Yoshikawa, 1999, Effects of phosphodiesterase inhibitors on cytokine production by microglia, Mult. Scler., 5, 126, 10.1177/135245859900500210 Zujovic, 2000, Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation, Glia, 29, 305, 10.1002/(SICI)1098-1136(20000215)29:4<305::AID-GLIA2>3.0.CO;2-V