Episodic memory impairment in patients with Alzheimer’s disease is correlated with entorhinal cortex atrophy

Galton CJ, Patterson K, Xuereb JH, Hodges JR (2000) Atypical and typical presentations of Alzheimer’s disease: a clinical, neuropsychological, neuroimaging and pathological study of 13 cases. Brain 123:484–498

Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239–259

Scoville WB, Milner B (1957) Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychiatry 20:11–21

Amaral DG, Insausti R (1990) Hippocampal formation. In: Paxinos G (ed) The human nervous system. Academic Press San Diego, pp 711–755

Schacter DL, Wagner AD (1999) Medial temporal lobe activations in fMRI and PET studies of episodic encoding and retrieval. Hippocampus 9:7–24

Vargha-Khadem F, Gadian DG, Watkins KE, Connelly A, Van Paesschen W, Mishkin M (1997) Differential effects of early hippocampal pathology on episodic and semantic memory. Science 277:376–380

Deweer B, Lehericy S, Pillon B, Baulac M, Chiras J, Marsault C, Agid Y, Dubois B (1995) Memory disorders in probable Alzheimer’s disease: the role of hippocampal atrophy as shown with MRI. J Neurol Neurosurg Psychiatry 58:590–597

Laakso MP, Soininen H, Partanen K, Helkala EL, Hartikainen P, Vainio P, Hallikainen M, Hanninen T, Riekkinen PJ Sr (1995) Volumes of hippocampus, amygdala and frontal lobes in the MRIbased diagnosis of early Alzheimer’s disease: correlation with memory functions. J Neural Transm Park Dis Dement Sect 9:73–76

Fox NC, Warrington EK, Freeborough PA, Hartikainen P, Kennedy AM, Stevens JM, Rossor MN (1996) Presymptomatic hippocampal atrophy in Alzheimer’s disease. A longitudinal MRI study. Brain 119:2001–2007

Petersen RC, Jack CR Jr, Xu YC, Waring SC, O’Brien PC, Smith GE, Ivnik RJ, Tangalos EG, Boeve BF, Kokmen E (2000) Memory and MRI-based hippocampal volumes in aging and AD. Neurology 54:581–587

Rombouts SA, Barkhof F, Witter MP, Scheltens P (2000) Unbiased wholebrain analysis of gray matter loss in Alzheimer’s disease. Neurosci Lett 285:231–233

Baron JC, Chetelat G, Desgranges B, Perchey G, Landeau B, de la Sayette V, Eustache F (2001) In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer’s disease. Neuroimage 14:298–309

Ohnishi T, Matsuda H, Tabira T, Asada T, Uno M (2001) Changes in brain morphology in Alzheimer disease and normal aging: is Alzheimer disease an exaggerated aging process? AJNR Am J Neuroradiol 22:1680–1685

Good CD, Scahill RI, Fox NC, Ashburner J, Friston KJ, Chan D, Crum WR, Rossor MN, Frackowiak RS (2002) Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias. Neuroimage 17:29–36

Frisoni GB, Testa C, Zorzan A, Sabattoli F, Beltramello A, Soininen H, Laakso MP (2002) Detection of gray matter loss in mild Alzheimer’s disease with voxel based morphometry. J Neurol Neurosurg Psychiatry 73:657–664

Busatto GF, Garrido GE, Almeida OP, Castro CC, Camargo CH, Cid CG, Buchpiguel CA, Furuie S, Bottino CM (2002) A voxel-based morphometry study of temporal lobe gray matter reductions in Alzheimer’s disease. Neurobiol Aging 24:221–231

Karas GB, Burton EJ, Rombouts SA, van Schijndel RA, O’Brien JT, Scheltens P, McKeith IG, Williams D, Ballard C, Barkhof F (2003) A comprehensive study of gray matter loss in patients with Alzheimer’s disease using optimized voxel-based morphometry. Neuroimage 18:895–907

Boxer AL, Rankin KP, Miller BL, Schuff N, Weiner M, Gorno-Tempini ML, Rosen HJ (2003) Cinguloparietal atrophy distinguishes Alzheimer disease from semantic dementia. Arch Neurol 60:949–956

Rémy F, Mirrashed F, Campbell B, Richter W (2005) Verbal episodic memory impairment in Alzheimer’s disease: a combined structural and functional MRI study. Neuroimage 25:253–266

Scahill RI, Schott JM, Stevens JM, Rossor MN, Fox NC (2002) Mapping the evolution of regional atrophy in Alzheimer’s disease: unbiased analysis of fluid-registered serial. MRI Proc Natl Acad Sci USA 99:4703–4707

Boxer AL, Kramer JH, Du AT, Schuff N, Weiner MW, Miller BL, Rosen HJ (2003) Focal right inferotemporal atrophy in AD with disproportionate visual constructive impairment. Neurology 61:1485–1491

Grossman M, McMillan C, Moore P, Ding L, Glosser G, Work M, Gee J (2004) What’s in a name: voxel-based morphometric analyses of MRI and naming difficulty in Alzheimer’s disease, frontotemporal dementia and corticobasal degeneration. Brain 127:628–649

Duvernoy HM (1998) The human hippocampus: functional anatomy, vascularization and serial sections with MRI, 2nd ed. Springer, Berlin

McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadian EM (1984) Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s disease. Neurology 34:939–944

Folstein MF, Folstein SE, McHigh PR (1975) The “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinicians. J of Psychiatr Res 12:189–198

Magni E, Binetti G, Bianchetti A, Rozzini R, Trabucchi M. (1996) Mini-Mental state examination: a normative study in italian elderly population. Eur J Neurol 3:1–21

Carlesimo GA, Caltagirone C Gainotti G, the group for the standardization of the Mental Deterioration Battery (1996) The Mental Deterioration Battery: normative data, diagnostic reliability and qualitative analyses of cognitive impairment. Eur Neurol 36:378–384

Carlesimo GA, Mauri A, Graceffa AMS, Fadda L Loasses A. Lorusso S, Caltagirone C (1998) Memory Performances in young, elderly, and very old healthy individuals versus patients with Alzheimer’s disease: evidence for discontinuity between normal and pathological aging. J Clin Exp Neuropsychol 20:14–29

Aggleton JP, Vann SD, Denby C, Dix S, Mayes AR, Roberts N, Yonelinas AP (2005) Sparing of the familiarity component of recognition memory in a patient with hippocampal pathology. Neuropsychologia 43:1810–1823

Pasquier F, Grymonprez L, Lebert F, Van der Linden M (2001) Memory impairment differs in frontotemporal dementia and Alzheimer’s disease. Neurocase 7:161–171

Caltagirone C, Gainotti G, Masullo C, Miceli G (1979) Validity of some neuropsychological tests in the assessment of mental deterioration. Acta Psychiatr Scand 60:50–56

Spinnler H, Tognoni G (1987) Standardizzazione e taratura italiana di test neuropsicologici. The Italian Journal of Neurological Science, suppl. 8

Rey A (1968). Reattivo della Figura Complessa. Manuale. (Complex Figure Task Manual). Ed. Organizzazioni Speciali O.S., Firenze

Wechsler D (1997) Wechsler Adult Intelligence Scale-Revised (WAIS-R). Ed. Organizzazioni Speciali O.S., Firenze

Milner B (1971) Interhemispheric differences and psychological processes. Br Med Bull 27:272–277

Good CD, Johnsrude IS, Ashburner J, Henson RNA, Friston KJ, Frackowiak RS (2001) A voxel-based morphometry study of ageing in 465 normal adult human brains. Neuroimage 14:21–26

Worsley KJ, Marrett S, Neelin P, Vandal AC, Friston KJ, Evans AC (1996) A unified statistical approach for determining significant signals in images of cerebral activation. Hum Brain Mapp 4:58–63

Pruessner JC, Li LM, Serles W, Pruessner M, Collins DL, Kabani N, Lupien S, Evans AC (2000) Volumetry of hippocampus and amygdala with highresolution MRI and three-dimensional analysis software: minimizing the discrepancies between laboratories. Cereb Cortex 10:433–442

Pruessner JC, Kohler S, Crane J, Pruessner M, Lord C, Byrne A, Kabani N, Collins DL, Evans AC (2002) Volumetry of temporopolar, perirhinal, entorhinal and parahippocampal cortex from high-resolution MR images: considering the variability of the collateral sulcus. Cereb Cortex 12:1342–1353

Douvernoy H (1991) The human brain, surface, three-dimensional section anatomy and MRI, Springer-Verlag Wien, New York

Van Hoesen GW, Augustinack JC, Dierking J, Redman SJ, Thangavel R (2000) The parahippocampal gyrus in Alzheimer’s disease. Clinical and preclinical neuroanatomical correlates. Ann N Y Acad Sci. 911:254–274

Hyman BT, Van Hoesen GW, Damasio AR (1990). Memory-related neural systems in Alzheimer’s disease: an anatomic study. Neurology 40:1721–1730

Squire LR, Stark CE, Clark RE (2004) The medial temporal lobe. Annu Rev Neurosci 27:279–306

Hyman BT, Van Hoesen GW, Kromer LJ, Damasio AR (1986) Perforant pathway changes and the memory impairment of Alzheimer’s disease. Ann Neurol 20:472–481

Eustache F, Desgranges B, Giffard B, de la Sayette V, Baron JC (2001) Entorhinal cortex disruption causes memory deficit in early Alzheimer’s disease as shown by PET. Neuroreport 12:683–685