An 18-mo randomized, double-blind, placebo-controlled trial of DHA-rich fish oil to prevent age-related cognitive decline in cognitively normal older adults

The American Journal of Clinical Nutrition - Tập 107 Số 5 - Trang 754-762 - 2018
Vanessa Danthiir1,2, Diane Hosking1,2, Ted Nettelbeck2, Andrew Vincent3, Carlene Wilson1,2, N. Callaghan1, Eva Calvaresi1, Peter Clifton1, Gary Wittert3
1Commonwealth Scientific and Industrial Research Organisation, Nutrition and Health
2School of Psychology,
3School of Medicine, University of Adelaide, Adelaide, Australia

Tóm tắt

Từ khóa


Tài liệu tham khảo

Cederholm, 2013, ω-3 fatty acids in the prevention of cognitive decline in humans, Adv Nutr, 4, 672, 10.3945/an.113.004556

Dyall, 2015, Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA, Front Aging Neurosci, 7, 52, 10.3389/fnagi.2015.00052

Uauy, 2006, Nutrition in brain development and aging: role of essential fatty acids, Nutr Rev, 64, S24, 10.1301/nr.2006.may.S24-S33

Parletta, 2013, Nutritional modulation of cognitive function and mental health, J Nutr Biochem, 24, 725, 10.1016/j.jnutbio.2013.01.002

Calder, 2012, Mechanisms of action of (n–3) fatty acids, J Nutr, 142, 592s, 10.3945/jn.111.155259

Mazereeuw, 2012, Effects of omega-3 fatty acids on cognitive performance: a meta-analysis, Neurobiol Aging, 33, 1482, 10.1016/j.neurobiolaging.2011.12.014

Dangour, 2010, Effect of 2-y n–3 long-chain polyunsaturated fatty acid supplementation on cognitive function in older people: a randomized, double-blind, controlled trial, Am J Clin Nutr, 91, 1725, 10.3945/ajcn.2009.29121

Chew, 2015, Effect of omega-3 fatty acids, lutein/zeaxanthin, or other nutrient supplementation on cognitive function: the AREDS2 randomized clinical trial, JAMA, 314, 791, 10.1001/jama.2015.9677

Johnson, 2008, Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women, Nutr Neurosci, 11, 75, 10.1179/147683008X301450

Nilsson, 2012, Effects of supplementation with n–3 polyunsaturated fatty acids on cognitive performance and cardiometabolic risk markers in healthy 51 to 72 years old subjects: a randomized controlled cross-over study, Nutr J, 11, 99, 10.1186/1475-2891-11-99

Witte, 2013, Long-chain omega-3 fatty acids improve brain function and structure in older adults, Cereb Cortex, 24, 3059, 10.1093/cercor/bht163

Stough, 2012, The effects of 90-day supplementation with the omega-3 essential fatty acid docosahexaenoic acid (DHA) on cognitive function and visual acuity in a healthy aging population, Neurobiol Aging, 33, 824, 10.1016/j.neurobiolaging.2011.03.019

van de Rest, 2008, Effect of fish oil on cognitive performance in older subjects: A randomized, controlled trial, Neurology, 71, 430, 10.1212/01.wnl.0000324268.45138.86

Külzow, 2016, Impact of omega-3 fatty acid supplementation on memory functions in healthy older adults, J Alzheimer's Dis, 51, 713, 10.3233/JAD-150886

Curran, 1999, The application of latent curve analysis to testing developmental theories in intervention research, Am J Commun Psychol, 27, 567, 10.1023/A:1022137429115

Muthén, 1997, General longitudinal modeling of individual differences in experimental designs: a latent variable framework for analysis and power estimation, Psychol Methods, 2, 371, 10.1037/1082-989X.2.4.371

Danthiir, 2011, Nutr J [Internet], 10, 1, 10.1186/1475-2891-10-1

Newkirk, 2004, Validation of a 26-point telephone version of the Mini-Mental State Examination, J Geriatr Psychiatry Neurol, 17, 81, 10.1177/0891988704264534

Swierk, 2011, Validation of an Australian electronic food frequency questionnaire to measure polyunsaturated fatty acid intake, Nutrition, 27, 641, 10.1016/j.nut.2010.06.011

Muthén, 1998

Lepage, 1986, Direct transesterification of all classes of lipids in a one-step reaction, J Lipid Res, 27, 114, 10.1016/S0022-2275(20)38861-1

Meyer, 2016, Australians are not meeting the recommended intakes for omega-3 long chain polyunsaturated fatty acids: results of an analysis from the 2011–2012 National Nutrition and Physical Activity Survey, Nutrients, 8, 111, 10.3390/nu8030111

Rothman, 1990, No adjustments are needed for multiple comparisons, Epidemiology, 1, 43, 10.1097/00001648-199001000-00010

Stonehouse, 2013, DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial, Am J Clin Nutr, 97, 1134, 10.3945/ajcn.112.053371

Chouinard-Watkins, 2014, Fatty acid metabolism in carriers of apolipoprotein E epsilon 4 allele: is it contributing to higher risk of cognitive decline and coronary heart disease?, Nutrients, 6, 4452, 10.3390/nu6104452

Caslake, 2008, Effect of sex and genotype on cardiovascular biomarker response to fish oils: the FINGEN Study, Am J Clin Nutr, 88, 618, 10.1093/ajcn/88.3.618

Pase, 2014, An evidence based method for examining and reporting cognitive processes in nutrition research, Am J Clin Nutr, 27, 232

Pase, 2013, Describing a taxonomy of cognitive processes for clinical trials assessing cognition, Am J Clin Nutr, 98, 509, 10.3945/ajcn.113.065532

Carroll, 1993, Human cognitive abilities: a survey of factor-analytic studies, Human cognitive abilities: a survey of factor-analytic studies

McRorie, 2004, Psychomotor movement and IQ, Person Indiv Differ, 37, 523, 10.1016/j.paid.2003.09.023

Salthouse, 1996, The processing-speed theory of adult age differences in cognition, Psychol Rev, 103, 403, 10.1037/0033-295X.103.3.403

Hohman, 2011, Subjective cognitive complaints and longitudinal changes in memory and brain function, Neuropsychology, 25, 125, 10.1037/a0020859

Maehre, 2015, ω-3 fatty acids and cardiovascular diseases: Effects, mechanisms and dietary relevance, Int J Mol Sci, 16, 22636, 10.3390/ijms160922636

Zuta, 2007, The effect of α-tocopherol on the oxidation of mackerel oil, Food Chem, 100, 800, 10.1016/j.foodchem.2005.11.003