Ecological niche modeling of Astragalus membranaceus var. mongholicus medicinal plants in Inner Mongolia, China

Scientific Reports - Tập 10 Số 1
Min Yang1, Ziyan Li1, Lanbo Liu2, Agula Bo3, Chunhong Zhang4, Minhui Li5
1Department of Pharmacy, Baotou Medical College, Baotou, 014060, China
2Baotou Meteorological Bureau of Inner Mongolia Autonomous Region, Baotou, 014030, China
3Inner Mongolia Key Laboratory of Characteristic Geoherbs Resources Protection and Utilization, Baotou Medical College, Baotou, 014060, China
4Inner Mongolia Key Laboratory of Chinese Medicinal Materials Resource, Baotou Medical College, Baotou, 014060, China
5Pharmaceutical Laboratory, Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot 010020, China

Tóm tắt

AbstractRadix Astragali is commonly used in traditional Chinese medicine, and its quality is closely related to ecological factors, such as climate and soil, in the production area. To provide high-quality Radix Astragali to Chinese and foreign markets, we used maximum entropy model and statistical analysis method, combined with data on ecological factors, Astragalusmembranaceus var. mongholicus geographical distribution, and index component content to predict the ecological suitability distribution of A.membranaceus var. mongholicus and establish the relationship between astragaloside IV and calycosin-7-glucoside in this species and ecological factors. Subsequently, we could determine the suitability regionalization of high-quality A.membranaceus var. mongholicus in Inner Mongolia, China. The results showed that the standard deviation of seasonal changes in temperature (40.6%), precipitation in October (15.7%), vegetation type (14.3%), soil type (9.2%), and mean sunshine duration in the growing season (9.1%) were the top five most influential factors out of the 17 main ecological factors affecting the distribution of A.membranaceus var. mongholicus. The standard deviation of seasonal changes in temperature, precipitation in October, precipitation in April, soil pH, and mean sunshine duration in the growing season were found to be the key ecological factors affecting the accumulation of astragaloside IV and calycosin-7-glucoside in A.membranaceus var. mongholicus. The regions with the highest-quality A.membranaceus var. mongholicus were distributed in Baotou (Guyang County), Hohhot (Wuchuan County), and central Wulanchabu (Chahar Right Middle Banner, Chahar Right Back Banner, and Shangdu County) and its surroundings in Inner Mongolia. Baotou, Hohhot, and their surrounding areas were the main traditional production areas of A.membranaceus var. mongholicus, and central Wulanchabu was a potentially suitable distribution area of this species. The main production areas were consistent with the actual production base of A.membranaceus var. mongholicus. This study therefore provides a scientific basis to guide the cultivation of A.membranaceus var. mongholicus.

Từ khóa


Tài liệu tham khảo

Zhang, C. H. et al. Ethnopharmacology, phytochemistry, pharmacology, toxicology and clinical applications of Radix Astragali. Chin. J. Integr. Med. https://doi.org/10.1007/s11655-019-3032-8 (2019).

Fu, J. et al. Review of the botanical characteristics, phytochemistry, and pharmacology of Astragalus membranaceus (Huangqi). Phytother. Res. 28, 1275–1283. https://doi.org/10.1002/ptr.5188 (2014).

The Tenth Chinese Pharmacopoeia Commission of the People’s Republic of China. Pharmacopoeia of the People’s Republic of China (The Medicine Science and Technology Press of China, Beijing, 2015).

Cheng, M., Chi, X. L., Wang, H. & Yang, G. Analysis of status and problems of international trade of Astragalus membranaceus in China. Mod. Chin. Med. 21, 12–16 (2019).

Qin, X. M. et al. Status and analysis of Astragali Radix resource in China. China J. Chin. Mater. Med. 38, 3234–3238 (2013).

Editorial committee of flora of China. Flora of China, Vol 42 272 (Science Press, Beijing, 1993).

Zhang, C. H. et al. Investigation and arrangement of ecological planting pattern of Astragalus Radix in Inner Mongolia. Mod. Chin. Med. 20, 1212–1224 (2018).

National Environmental Protection Agency of the People’s Republic of China. List of rare and endangered plants in China. Bull. Biol. 7, 25–30 (1987).

Nan, H. J. Study on quality control and estimation of Radix Astragali. Master's thesis. Shanxi University, Taiyuan, China (2009).

Zhang, S. Y., Piao, H. S. & Song, C. Y. Study on the relation between duration of cultivation of plant and content of chemical components in Astragalus. J. Med. Sci. Yanbian Univ. 28, 87–89 (2005).

Shao, J. M., Lian, Y. F., Yan, L. H. & Wang, L. H. Comparative analysis of total saponins in Astragalus membranaceus from different habitats. Shaanxi J. Tradit. Chin. Med. 39, 268–270 (2018).

Li, J. et al. Investigation of planting bases of Astragali Radix. Chin. Arch. Tradit. Chin. Med. 32, 18–21 (2014).

Liu, D. W. et al. Resource surveys and suitability of origin for genuine medicinal materials, Astragalus membranaceus var. mongholicus in Inner Mongolia, China. Chin. J. Appl. Ecol. 27, 838–844 (2016).

Yang, F. R., Zhang, Q., Sun, C. H., Xie, C. X. & Song, J. Y. Comparative evaluation of multiple models for predicting the potential distribution areas of Astragalus membranaceus var mongholicus. Plant Sci. J. 37, 136–143 (2019).

Bao, X. L. The structure of geographical environment and the regularity of its regional differentiation in Inner Mongolia. J. Inner Mongolia Teach. Coll. Natl. 12, 84–86 (1997).

Sun, S. Y. & Chen, G. L. Current situation, problems and countermeasures of Radix Astragali industrialization in Inner Mongolia. Mol. Plant Breed. 16, 5126–5133 (2018).

Akpoti, K., Kabo-bah, A. T., Dossou-Yovo, E. R., Groen, T. A. & Zwart, S. J. Mapping suitability for rice production in inland valley landscapes in Benin and Togo using environmental niche modeling. Sci. Total Environ. 709, 136165 (2020).

Akpoti, K., Kabo-bah, A. T. & Zwart, S. J. Agricultural land suitability analysis: State-of-the-art and outlooks for integration of climate change analysis. Agric. Syst. 173, 172–208 (2019).

Phillips, S. J. Dudík, M., & Schapire, R. E. A maximum entropy approach to species distribution modeling. In Proc. Twenty-First International Conference on Machine Learning, pp. 655–662 (2004).

Phillips, S. J., Anderson, R. P. & Schapire, R. E. Maximum entropy modeling of species geographic distributions. Ecol. Model. 190, 231–259 (2006).

Peterson, A. T. Predicting the geography of species’ invasions via ecological niche modeling. Q. Rev. Biol. 78, 419–433 (2003).

Zhang, L., Cao, B., Bai, C., Li, G. & Mao, M. Predicting suitable cultivation regions of medicinal plants with Maxent modeling and fuzzy logics: A case study of Scutellaria baicalensis in China. Environ. Earth Sci. 75, 361 (2016).

Khanum, R., Mumtaz, A. S. & Kumar, S. Predicting impacts of climate change on medicinal asclepiads of Pakistan using Maxent modeling. Acta Oecol. 49, 23–31 (2013).

Zhu, S. D. et al. Regionalization of Chinese material medical quality based on maximum entropy model: A case study of Atractylodes lancea. Sci. Rep. 7, 42417 (2017).

Li, Z. Y. et al. Ecological modeling of Cistanche deserticola Y.c. Ma in Alxa, China. Sci. Rep. 9, 13134 (2019).

Wang, Y., Zhang, L., Du, Z. X., Pei, J. & Huang, L. F. Chemical diversity and prediction of potential cultivation areas of Cistanche Herbs. Sci. Rep. 9, 19737 (2019).

Zhang, H. T., Wang, J., Cheng, M. E., Duan, H. Y. & Peng, H. S. Investigation on main cultivation of Astragalus membranaceus var. mongholicus and commercial specifications grades. J. Chin. Med. Mater. 38, 2487–2492 (2015).

Wang, L. S. et al. Salt stress changes chemical composition in Limonium bicolor (Bag.) Kuntze, a medicinal halophytic plant. Ind. Crops Prod. 84, 248–253 (2016).

Alhaithloul, H. A., Soliman, M. H., Ameta, K. L., El-Esawi, M. A. & Elkelish, A. Changes in ecophysiology, osmolytes, and secondary metabolites of the medicinal plants of Mentha piperita and Catharanthus roseus subjected to drought and heat stress. Biomolecules 10, 43 (2020).

Li, W. C. A brief talk on the domestic and foreign market of plant extract. Pharm. Chem. 1, 27–29 (2007).

Ren, R. B. Analysis of industry market of Chinese natural plant extract. Chem. Intermediate 28, 66–67 (2018).

Hou, Y. Key techniques for growing Astragalus membranaceus (Fisch.) Bunge. Spec. Econ. Anim. Plant. 15, 39 (2012).

Yuan, H., Zhang, S. F., Jia, S. H. & Chen, N. Progress in application and biological active of Radix Astragali in health foods. Food Sci. 35, 330–334 (2014).

Huang, X., Xu, J. & Ma, W. Application and prospect of traditional Chinese Medicine Astragalus on medical cosmetology. Chin. J. Aesthet. Med. 26, 123–125 (2017).

Booker, A. & Heinrich, M. Value chains of botanical and herbal medicinal products: A European perspective. Herbalgram 112, 40–45 (2016).

Anthony, B., Deborah, J. & Michael, H. Value chains of herbal medicines—research needs and key challenges in the context of ethnopharmacology. J. Ethnopharmacol. 140, 624–633 (2012).

Anthony, B., Deborah, J. & Michael, H. Value chains of herbal medicines—ethnopharmacological and analytical challenges in a globalizing world. Evid. Based Valid. Herbal Med. 2, 29–44 (2015).

Huang, L. F. & Chen, S. L. Quality ecology on Chinese medicines: New emerging cross discipline. Chin. J. Exp. Tradit. Med. Form. 23, 1–11 (2017).

Cao, H. X. Effects of scientific research on the development of traditional Chinese medicine and pharmacology. China J. Tradit. Chin. Med. Pharm. 20, 129–131 (2005).

Dai, L. L. et al. Effects of plastic film mulching cultivation with ridge and furrow system on soil water, temperature and yield of Astragali Radix in dry land. J. Chin. Med. Mater. 40, 1997–2001 (2017).

Peter, A. A. A trial to tackle tiger mosquitoes. Nature https://doi.org/10.1038/d41586-019-02000-0 (2019).

Kira, T. A new classification of climate in eastern Asia as the basis for agricultural geography. Horic. Inst. Kyoto Univ. Kyoto. 20, 1–23 (1945).

Xu, W. D. The relation between distribution of edificator and companion in zonal vegetation and water-temperature condition in Northeast China. Acta Bot. Sin. 25, 264–274 (1983).

Bi, Y. Q. et al. Present condition analysis and countermeasures of Chinese and Mongolian medicine resources in the inner Mongolia Autonomous Region. Mod. Chin. Med. 19, 895–900 (2017).

Kumar, S., Graham, J., West, A. M. & Evangelista, P. H. Using district-level occurrences in MaxEnt for predicting the invasion potential of an exotic insect pest in India. Comput. Electron. Agric. 103, 55–62 (2014).

Hanley, J. A. & McNeil, B. J. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 143, 29–36 (1982).

Lobo, J. M., Jiménez-Valverde, A. & Real, R. AUC: A misleading measure of the performance of predictive distribution models. Glob. Ecol. Biogeogr. 17, 145–151 (2010).

British Pharmacopoeia Commission. British Pharmacopoeia (Herbal Drug Preparations and Herbal Medicinal Products) (The Stationery Office, England, 2019).

European Pharmacopoeia Commission. European Pharmacopoeia (European Directorate for the Quality of Medicines and Health Care, Strasbourg, 2017).

Thông tin
Thông tin xuất bản

Scientific Reports

Tập 10 Số 1

Thông tin tác giả