COVID-19 and Cardiovascular Disease

Circulation Research - Tập 128 Số 8 - Trang 1214-1236 - 2021
Mina K. Chung1,2, David A. Zidar3,4, Michael R. Bristow5, Scott J. Cameron1,6,7, Timothy A. Chan1,6,8, Clifford V. Harding9, Deborah Kwon1,6,10, Tamanna Singh1,6,11, John C. Tilton12, Emily J. Tsai13, Nathan R. Tucker14,15, John Barnard6,16, Joseph Loscalzo17
1Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
2Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, 9500 Euclid Ave, J2-2, Cleveland, OH 44195.
3David A. Zidar Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH. Louis Stokes Cleveland Veterans Affairs Medical Center, OH (D.A.Z.).
4Louis Stokes Cleveland Veterans Affairs Medical Center, OH (D.A.Z.).
5Michael R. Bristow https://orcid.org/0000-0002-8860-4698 University of Colorado Anschutz Medical Center, Aurora (M.R.B.).
6Cleveland Clinic Lerner College of Medicine (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH.
7Scott J. Cameron https://orcid.org/0000-0002-9616-1540 Cleveland Clinic (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH. Cleveland Clinic Lerner College of Medicine (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH. Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
8Timothy Chan Cleveland Clinic (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH. Cleveland Clinic Lerner College of Medicine (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH. Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
9Clifford V. Harding III https://orcid.org/0000-0002-6333-162X Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
10Deborah H. Kwon Cleveland Clinic (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH. Cleveland Clinic Lerner College of Medicine (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH. Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
11Tamanna Singh Cleveland Clinic (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH. Cleveland Clinic Lerner College of Medicine (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH. Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
12John C. Tilton Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
13Emily J. Tsai Columbia University Vagelos College of Physicians and Surgeons, New York (E.J.T.).
14Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Boston, MA (N.R.T.).
15Nathan R. Tucker https://orcid.org/0000-0002-5071-4218 Masonic Medical Research Institute, Utica, NY (N.R.T.). Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Boston, MA (N.R.T.).
16John Barnard https://orcid.org/0000-0003-2403-8268 Cleveland Clinic (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH. Cleveland Clinic Lerner College of Medicine (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH.
17Joseph Loscalzo https://orcid.org/0000-0002-1153-8047 Brigham and Women's Hospital, Harvard Medical School, Boston, MA (J.L.).

Tóm tắt

A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential consequences on the cardiovascular health of millions of people who survive infection worldwide. Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the etiologic agent of COVID-19, can infect the heart, vascular tissues, and circulating cells through ACE2 (angiotensin-converting enzyme 2), the host cell receptor for the viral spike protein. Acute cardiac injury is a common extrapulmonary manifestation of COVID-19 with potential chronic consequences. This update provides a review of the clinical manifestations of cardiovascular involvement, potential direct SARS-CoV-2 and indirect immune response mechanisms impacting the cardiovascular system, and implications for the management of patients after recovery from acute COVID-19 infection.

Từ khóa


Tài liệu tham khảo

10.1001/jamacardio.2020.3557

10.1016/j.jacc.2020.06.068

10.1016/j.jacc.2020.08.069

10.1001/jamacardio.2020.1017

10.1001/jamacardio.2020.0950

10.1016/S0140-6736(20)30566-3

10.3390/v11010059

10.1093/eurheartj/ehaa231

https://www.cdc.gov/sars/about/fs-sars.html. Accessed December 13 2020.

https://www.who.int/publications/m/item/summary-of-probable-sars-cases-with-onset-of-illness-from-1-november-2002-to-31-july-2003. Accessed December 13 2020.

World Health Organization. Middle East Respiratory Syndrome. 2020. http://www.emro.who.int/health-topics/mers-cov/mers-outbreaks.html. Accessed December 13 2020.

https://coronavirus.jhu.edu/map.html. Accessed April 2 2021.

10.1038/s41598-020-75848-2

Anupama, BK, Chaudhuri, D. A review of acute myocardial injury in coronavirus disease 2019. Cureus. 2020;12:e8426.

10.1038/s41586-020-2012-7

10.1038/s41586-020-2008-3

10.1038/s41586-020-2180-5

10.1016/j.cell.2020.02.058

10.1161/01.CIR.0000094733.61689.D4

10.1161/01.CIR.0000094734.67990.99

10.1038/nature02145

10.1001/jama.2020.12603

10.1126/science.abd3072

10.1016/j.jmb.2018.06.024

10.1016/j.jacbts.2020.06.007

Beddingfield, BJ, Iwanaga, N, Chapagain, PP, Zheng, W, Roy, CJ, Hu, TY, Kolls, JK, Bix, GJ. The integrin binding peptide, ATN-161, as a novel therapy for SARS-CoV-2 infection. JACC Basic Transl Sci. 2020;6:1–8.

10.1016/j.jacbts.2020.07.005

10.1016/j.cell.2020.02.052

10.1016/j.chom.2020.11.004

10.1161/CIRCULATIONAHA.120.052824

10.1016/j.jacbts.2021.01.002

10.1097/CCM.0000000000002053

10.1016/S0140-6736(04)15788-7

10.1073/pnas.0400576101

10.1073/pnas.0505577102

10.1074/jbc.M508381200

10.1016/j.molcel.2020.04.022

10.1038/s41586-020-2179-y

10.1016/j.cell.2020.03.045

10.1038/s41467-020-15562-9

10.1038/s41586-020-2380-z

10.1016/j.celrep.2020.107725

10.1126/science.abb7269

10.1038/s41467-020-16256-y

10.1038/s41586-020-2349-y

10.1038/s41594-020-0480-y

10.1126/science.abc7424

10.1186/s12916-020-01673-z

10.1186/s12967-020-02486-7

10.1038/s41588-020-00759-x

10.2807/1560-7917.ES.2020.26.1.2002106

10.1016/j.chom.2021.02.003

10.1038/s41579-020-00468-6

10.1073/pnas.0409465102

10.1038/nature12711

10.1038/nrmicro817

10.1161/01.res.87.5.e1

10.1093/cvr/cvaa078

10.1093/eurheartj/ehaa311

10.1161/CIRCULATIONAHA.120.047911

10.15252/msb.20209610

10.1093/cvr/cvaa191

10.1172/JCI118186

10.1038/nature00786

10.1161/01.HYP.0000205833.89478.5b

10.1074/jbc.M311191200

10.1002/jcp.29802

10.1016/j.mayocp.2020.04.028

10.1186/1741-7015-2-19

10.1007/s00134-020-05985-9

10.1136/bmj.m1996

10.1007/s15010-020-01473-w

10.1136/heartjnl-2020-317056

10.1001/jama.2020.1585

10.1093/ehjci/jeaa178

10.1161/CIRCULATIONAHA.120.047971

10.1016/j.echo.2020.06.009

10.1016/j.cjca.2020.05.030

10.1111/jce.14772

10.1016/j.mayocp.2020.10.031

10.1016/j.eclinm.2020.100630

10.1007/s11606-020-06081-w

10.1001/jama.2020.6548

10.1007/s11606-020-06083-8

10.1161/CIRCULATIONAHA.120.052278

10.1111/jth.14768

10.3389/fcvm.2020.598400

10.1161/CIRCULATIONAHA.120.050434

10.1016/j.jacc.2020.06.007

10.1097/RTI.0000000000000574

10.1016/j.jcmg.2020.05.004

10.1001/jamacardio.2020.4916

10.1161/CIRCULATIONAHA.120.052573

10.1001/jamacardio.2020.7444

10.1186/s12968-017-0350-x

10.1016/j.jacc.2017.08.050

10.1161/CIRCULATIONAHA.118.035319

10.1016/j.jacc.2019.08.1061

10.1016/S0140-6736(20)32656-8

10.1093/infdis/165.1.134

10.1093/eurheartj/ehaa664

10.1161/CIRCULATIONAHA.120.049465

10.7326/L20-0882

10.1001/jama.2020.8907

10.1001/jamacardio.2020.3551

10.1002/ehf2.12805

10.1002/ejhf.1828

10.1016/S2352-4642(20)30257-1

10.1161/STROKEAHA.120.032764

10.1093/cvr/cvaa267

10.3390/biomedicines8120626

10.1164/rccm.202008-3265OC

10.1016/S2213-2600(20)30243-5

10.1016/j.carpath.2020.107300

10.1038/s41422-020-00412-6

10.1016/j.stemcr.2020.11.003

10.1186/s13287-020-02033-7

10.1016/j.xcrm.2020.100052

10.1016/S2665-9913(20)30173-9

10.1056/NEJMoa2028836

10.1056/NEJMoa2030340

10.1001/jamainternmed.2020.6820

10.1126/science.abc6027

10.1016/j.immuni.2020.07.026

10.1126/science.abd4585

10.3390/cells9092046

10.1038/s41392-020-00296-3

10.1016/j.cell.2020.09.038

10.1016/j.cell.2020.05.015

10.1101/2020.12.08.416636

10.1007/s00705-009-0409-6

10.1038/s41577-020-0389-z

10.1093/infdis/jiz051

10.1128/JVI.00671-11

10.1073/pnas.89.4.1320

10.1016/0090-1229(87)90164-4

10.1038/s41591-020-0965-6

10.1038/s41577-020-0359-5

10.1038/s41586-020-2538-8

10.1001/jama.2020.13372

Elbadawi, A, Elgendy, IY, Sahai, A, Bhandari, R, McCarthy, M, Gomes, M, Bishop, GJ, Bartholomew, JR, Kapadia, S, Cameron, SJ. Incidence and outcomes of thrombotic events in symptomatic patients with COVID-19. Arterioscler Thromb Vasc Biol. 2020;41:545–547.

10.3389/fimmu.2019.02884

10.1161/ATVBAHA.120.315033

10.1007/s11926-019-0815-z

Zuo, Y, Yalavarthi, S, Shi, H, Gockman, K, Zuo, M, Madison, JA, Blair, C, Weber, A, Barnes, BJ, Egeblad, M, et al. Neutrophil extracellular traps in COVID-19. JCI Insight. 2020;5:e138999.

10.3389/fimmu.2020.02063

10.1084/jem.20201129

10.1182/blood.2020007214

10.1161/CIRCRESAHA.120.317703

10.1186/s13045-020-00954-7

10.1038/s41591-020-0868-6

10.1016/j.omtm.2020.05.013

10.1016/j.trsl.2017.11.006

10.1038/s42255-020-00324-0

10.1182/blood-2010-02-268508

10.1161/ATVBAHA.110.207498

10.1111/all.14429

10.1161/CIRCRESAHA.107.157990

10.1161/ATVBAHA.118.311186

10.1016/j.rmed.2020.106176

10.1016/j.jacc.2020.03.031

10.1056/NEJMoa2002032

10.1038/s41421-020-0147-1

10.1126/science.abb2762

10.1186/s12959-020-00229-8

10.3390/antib9040052

10.3389/fimmu.2020.584241

10.1056/NEJMc2007575

10.1038/s41586-020-2286-9

10.1126/scitranslmed.abd3876

10.2450/2020.0164-20

10.1002/rth2.12390

10.1177/2324709620944091

10.1182/blood.2020008762

10.1001/jama.2020.17021

10.1056/NEJMoa2021436

10.1001/jamacardio.2020.1855

10.1016/j.ebiom.2020.102907

10.1056/NEJMsr2005760

10.1186/s13054-020-03015-0

10.1007/s11427-020-1643-8

10.1016/S2213-2600(20)30418-5

10.1038/nm1267

10.1038/s41392-020-00352-y

10.1056/NEJMoa2034577

10.1056/NEJMoa2035389

10.1016/j.cell.2006.02.007

10.1016/j.cell.2020.04.004

10.1111/1440-1681.13251

10.1128/mBio.01935-20

10.1038/s41401-020-00556-6

10.5582/bst.2020.03345

10.3390/pathogens9110917

10.1126/science.1257601

10.1038/s41467-018-05116-5

10.1038/s41467-019-10744-6

10.1096/fj.202001062R

Gysi, DM, Do Valle, I, Zitnik, M, Ameli, A, Gan, X, Varol, O, Sanchez, H, Baron, RM, Ghiassian, D, Loscalzo, J, et al. Network medicine framework for identifying drug repurposing opportunities for COVID-19. ArXiv. Preprint posted online April 15 2020.

10.1371/journal.pbio.3000970

10.1001/jamacardio.2020.3575

10.1080/14779072.2021.1844005

10.1111/jce.14479

10.1016/j.hrthm.2020.12.007

10.1007/s10286-020-00727-9

10.19102/icrm.2020.111102

10.1101/2020.08.31.20185140

10.1016/j.jcmg.2020.10.005

10.1016/j.jacc.2017.01.015

10.1001/jamacardio.2020.2136

Kim, JH, Levine, BD, Phelan, D, Emery, MS, Martinez, MW, Chung, EH, Thompson, PD, Baggish, AL. Coronavirus disease 2019 and the athletic heart: emerging perspectives on pathology, risks, and return to play. JAMA Cardiol. 2020;6:219–227.

10.1161/CIR.0000000000000239

10.1161/CIRCULATIONAHA.120.049252

Thông tin
Thông tin xuất bản

Circulation Research

Tập 128 Số 8

1214-1236

Thông tin tác giả