Excitotoxic effects of non-NMDA receptor agonists in organotypic corticostriatal slice cultures

Brain Research - Tập 841 - Trang 143-159 - 1999
Bjarne W Kristensen1,2,3, Jens Noraberg2, Birthe Jakobsen3, Jan Bert Gramsbergen3, Bjarke Ebert4, Jens Zimmer2,3
1Neuroscience Pharmabiotec, DK-5000 Odense C, Denmark
2NeuroScreen Ltd., DK-5000 Odense C, Denmark
3Department of Anatomy and Neurobiology, SDU-Odense University, DK-5000 Odense C, Denmark
4Department of Pharmacology, The Royal Danish School of Pharmacy, DK 2100 Copenhagen, Denmark

Tài liệu tham khảo

D.G. Altman, Practical Statistics for Medical Research, Chapman & Hall, London, 1991, 611 pp. Bahn, 1994, Kainate receptor gene expression in the developing rat brain, J. Neurosci., 14, 5525, 10.1523/JNEUROSCI.14-09-05525.1994 Barth, 1997, Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide, Brain Res., 762, 79, 10.1016/S0006-8993(97)00348-X Beal, 1986, Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid, Nature, 321, 168, 10.1038/321168a0 Beal, 1989, Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions, Synapse, 3, 38, 10.1002/syn.890030106 Best, 1996, Pre-exposure to subtoxic levels prevents kainic acid lesions in organotypic hippocampal slice cultures: effects of kainic acid on parvalbumin-immunoreactive neurons and expression of heat shock protein 72 following the induction of tolerance, Eur. J. Neurosci., 8, 1209, 10.1111/j.1460-9568.1996.tb01289.x Biziere, 1978, Influence of corticostriatal afferents on neostriatal kainate neurotoxicity, Neurosci. Lett., 8, 303, 10.1016/0304-3940(78)90140-4 Bradford, 1976, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72, 248, 10.1016/0003-2697(76)90527-3 Brewer, 1993, Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination, J. Neurosci. Res., 35, 567, 10.1002/jnr.490350513 Chen, 1995, Glutamate-mediated excitotoxic death of cultured striatal neurons is mediated by non-NMDA receptors, Exp. Neurol., 136, 212, 10.1006/exnr.1995.1098 Choi, 1992, Excitotoxic cell death, J. Neurobiol., 23, 1261, 10.1002/neu.480230915 Coyle, 1976, Lesion of striatal neurones with kainic acid provides a model for Huntington's chorea, Nature, 263, 244, 10.1038/263244a0 Dahl-Jørgensen, 1999, Serum and CNTF stimulate oligodendroglia and reduce fiber ourgrowth from striatal cultures, Exp. Neurol., 157, 88, 10.1006/exnr.1999.7035 Dawson, 1995, Excitotoxins, aging, and environmental neurotoxins: implications for understanding human neurodegenerative diseases, Toxicol. Appl. Pharmacol., 134, 1, 10.1006/taap.1995.1163 Frandsen, 1989, Direct evidence that excitotoxicity in cultured neurons is mediated via N-methyl-D-aspartate (NMDA) as well as non-NMDA receptors, J. Neurochem., 53, 297, 10.1111/j.1471-4159.1989.tb07327.x Friberg, 1998, Differential localization of the mRNAs for the pertussis toxin insensitive G-protein alpha sub-units gq, G11, and Gz in the rat brain, and regulation of their expression after striatal deafferentation, Mol. Brain Res., 54, 298, 10.1016/S0169-328X(97)00346-X Galarraga, 1990, Quinolinate and kainate neurotoxicity in neostriatal cultures is potentiated by co-culturing with neocortical neurons, Brain Res., 512, 269, 10.1016/0006-8993(90)90636-P Herb, 1992, The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits, Neuron, 8, 775, 10.1016/0896-6273(92)90098-X C.R. Houser, J.E. Vaughn, S.H.C. Hendry, E.G. Jones, A. Peters, GABA neurons in the cerebral cortex, in: E.G. Jones, A. Peters (Eds.), Cerebral Cortex, Vol. 2, Plenum, New York, 1984, pp. 63–89. Hsu, 1994, Adenosinergic modulation of CA1 neuronal tolerance to glucose deprivation in organotypic hippocampal cultures, Neurosci. Lett., 178, 189, 10.1016/0304-3940(94)90756-0 Jensen, 1998, AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization, Neurochem. Int., 32, 505, 10.1016/S0197-0186(97)00130-7 Juurlink, 1993, Ischemia-induced death of astrocytes and neurons in primary culture: pitfalls in quantifying neuronal cell death, Dev. Brain Res., 71, 239, 10.1016/0165-3806(93)90175-A Keilhoff, 1993, Comparison of double fluorescence staining and LDH-test for monitoring cell viability in vitro, NeuroReport, 5, 129, 10.1097/00001756-199311180-00008 Keinanen, 1990, A family of AMPA-selective glutamate receptors, Science, 249, 556, 10.1126/science.2166337 Koh, 1987, Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay, J. Neurosci. Methods, 20, 83, 10.1016/0165-0270(87)90041-0 Kohler, 1978, Perforant path transection protects hippocampal granule cells from kainate lesion, Neurosci. Lett., 10, 241, 10.1016/0304-3940(78)90233-1 Kristensen, 1998, Regional vulnerability of organotypic corticostriatal slice cultures to non-NMDA agonists detected by propidium iodide, Fluoro-Jade, and LDH release, Soc. Neurosci. Abs., 180, 465 Lipton, 1994, Excitatory amino acids as a final common pathway for neurologic disorders, N. Engl. J. Med., 330, 613, 10.1056/NEJM199403033300907 London, 1979, Specific binding of [3H]kainic acid to receptor sites in rat brain, Mol. Pharmacol., 15, 492 Macklis, 1990, Progressive incorporation of propidium iodide in cultured mouse neurons correlates with declining electrophysiological status: a fluorescence scale of membrane integrity, J. Neurosci. Methods, 31, 43, 10.1016/0165-0270(90)90007-3 Massieu, 1994, 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline protects against both AMPA and kainate-induced lesions in rat striatum in vivo, Neuroscience, 59, 931, 10.1016/0306-4522(94)90296-8 McGeer, 1978, Kainate-induced degeneration of neostriatal neurons: dependency upon corticostriatal tract, Brain Res., 139, 381, 10.1016/0006-8993(78)90941-1 Nadler, 1980, Kainic acid neurotoxicity toward hippocampal formation: dependence on specific excitatory pathways, Brain Res., 195, 47, 10.1016/0006-8993(80)90865-3 Newell, 1995, Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures, J. Neurosci., 15, 7702, 10.1523/JNEUROSCI.15-11-07702.1995 Nicoletti, 1987, Lesions of putative glutamatergic pathways potentiate the increase of inositol phospholipid hydrolysis elicited by excitatory amino acids, Brain Res., 436, 103, 10.1016/0006-8993(87)91561-7 Noraberg, 1998, Quantitation and regional distribution of trimethyltin (TMT) neurotoxicity in organotypic rat hippocampal cultures, Brain Res., 783, 305, 10.1016/S0006-8993(97)01358-9 Noraberg, 1999, Markers for neuronal degeneration in organotypic slice cultures, Brain Res. Protoc., 3, 278, 10.1016/S1385-299X(98)00050-6 G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, San Diego, CA, 1998. Pellegrini Giampietro, 1998, mGLUR1 antagonists reduce ischemic neuronal death in vivo and in vitro, Soc. Neurosci. Abs., 431, 1089 Plenz, 1996, Neural dynamics in cortex-striatum co-cultures: II. Spatiotemporal characteristics of neuronal activity, Neuroscience, 70, 893, 10.1016/0306-4522(95)00405-X Plenz, 1996, Neural dynamics in cortex-striatum co-cultures: I. Anatomy and electrophysiology of neuronal cell types, Neuroscience, 70, 861, 10.1016/0306-4522(95)00406-8 Plenz, 1996, Organotypic cortex-striatum-mesencephalon cultures: the nigrostriatal pathway, Neurosci. Lett., 209, 177, 10.1016/0304-3940(96)12644-6 Plenz, 1998, Up and down states in striatal medium spiny neurons simultaneously recorded with spontaneous activity in fast-spiking interneurons studied in cortex-striatum-substantia nigra organotypic cultures, J. Neurosci., 18, 266, 10.1523/JNEUROSCI.18-01-00266.1998 Portera-Cailliau, 1997, Excitotoxic cell death is topologically organized in newborn forebrain: preferentially vulnerability of neurons in neurocortical barrels and neostriatal striosomes, Soc. Neurosci. Abs., 895, 2294 Pozzo Miller, 1994, Spontaneous pyramidal cell death in organotypic slice cultures from rat hippocampus is prevented by glutamate receptor antagonists, Neuroscience, 63, 471, 10.1016/0306-4522(94)90544-4 Pringle, 1997, Neuroprotection by both NMDA and non-NMDA receptor antagonists in in vitro ischemia, Brain Res., 755, 36, 10.1016/S0006-8993(97)00089-9 Pringle, 1996, Brain-derived neurotrophic factor, but not neurotrophin-3, prevents ischaemia-induced neuronal cell death in organotypic rat hippocampal slice cultures, Neurosci. Lett., 211, 203, 10.1016/0304-3940(96)12745-2 Romijn, 1988, Hypoxia preferentially destroys GABAergic neurons in developing rat neocortex explants in culture, Exp. Neurol., 100, 332, 10.1016/0014-4886(88)90112-4 Sakaguchi, 1997, Dual mode of N-methyl-D-aspartate-induced neuronal death in hippocampal slice cultures in relation to N-methyl-D-aspartate receptor properties, Neuroscience, 76, 411, 10.1016/S0306-4522(96)00403-4 Schmued, 1997, Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration, Brain Res., 751, 37, 10.1016/S0006-8993(96)01387-X Schmued, 1998, Fluoro-Jade B: a Bis homolog of Fluoro-Jade with improved degenerate neuron staining properties, Soc. Neurosci. Abs., 423, 1064 Schwob, 1980, Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid. A histological study, Neuroscience, 5, 991, 10.1016/0306-4522(80)90181-5 Sheardown, 1990, 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia, Science, 247, 571, 10.1126/science.2154034 Sommer, 1990, Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS, Science, 249, 1580, 10.1126/science.1699275 Stoppini, 1991, A simple method for organotypic cultures of nervous tissue, J. Neurosci. Methods, 37, 173, 10.1016/0165-0270(91)90128-M Thomas, 1998, Organotypic brain slice cultures for functional analysis of alcohol-related disordes: novel versus conventional preparations, Alcoholism: Clin. Exp. Res., 22, 51 A. Vassault, Lactate Dehydrogenase, UV-method with pyruvate and NADH, in: H.U. Bergmeyer, J. Bergmeyer, M. Grossl (Eds.), Methods of Enzymatic Analysis, 1983, pp. 118–126. Vitale, 1993, Differential kinetics of propidium iodide uptake in apoptotic and necrotic thymocytes, Histochemistry, 100, 223, 10.1007/BF00269095 Vornov, 1998, Regional vulnerability to endogenous and exogenous oxidative stress in organotypic hippocampal culture, Exp. Neurol., 149, 109, 10.1006/exnr.1997.6673 Vornov, 1991, Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures, Exp. Neurol., 114, 11, 10.1016/0014-4886(91)90079-R Vornov, 1994, Delayed protection by MK-801 and tetrodotoxin in a rat organotypic hippocampal culture model of ischemia, Stroke, 25, 457, 10.1161/01.STR.25.2.457 West, 1996, Estimation of the number of somatostatin neurons in the striatum: an in situ hybridization study using the optical fractionator method, J. Comp. Neurol., 370, 11, 10.1002/(SICI)1096-9861(19960617)370:1<11::AID-CNE2>3.0.CO;2-O West, 1999, Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias, Trends Neurosci., 22, 51, 10.1016/S0166-2236(98)01362-9 Whetsell, 1996, Current concepts of excitotoxicity, J. Neuropathol. Exp. Neurol., 55, 1, 10.1097/00005072-199601000-00001 Whetsell, 1983, The organotypic tissue culture model of corticostriatal system used for examining amino acid neurotoxicity and its antagonism: studies on kainic acid, quinolinic acid and (−) 2-amino-7-phosphonoheptanoic acid, J. Neural Transm., Suppl., 19, 53 Wilson, 1972, Markers for gene expression in cultured cells from the nervous system, J. Biol. Chem., 247, 3159, 10.1016/S0021-9258(19)45227-7 Wisden, 1993, A complex mosaic of high-affinity kainate receptors in rat brain, J. Neurosci., 13, 3582, 10.1523/JNEUROSCI.13-08-03582.1993 Wullner, 1994, Glutamate receptor expression in rat striatum: effect of deafferentation, Brain Res., 647, 209, 10.1016/0006-8993(94)91320-X Wullner, 1997, Differential expression of kainate receptors in the basal ganglia of the developing and adult rat brain, Brain Res., 768, 215, 10.1016/S0006-8993(97)00645-8 Østergaard, 1993, Organotypic slice cultures of the rat striatum: I. A histochemical and immunocytochemical study of acetylcholinesterase, choline acetyltransferase, glutamate decarboxylase and GABA, Neuroscience, 53, 679, 10.1016/0306-4522(93)90616-N Østergaard, 1995, Organotypic slice cultures of the rat striatum: an immunocytochemical, histochemical and in situ hybridization study of somatostatin, neuropeptide Y, nicotinamide adenine dinucleotide phosphate-diaphorase, and enkephalin, Exp. Brain Res., 103, 70, 10.1007/BF00241966 Østergaard, 1991, Tyrosine hydroxylase immunoreactive neurons in organotypic slice cultures of the rat striatum and neocortex, Exp. Brain Res., 83, 357, 10.1007/BF00231159 Østergaard, 1990, Rat ventral mesencephalon grown as organotypic slice cultures and co-cultured with striatum, hippocampus, and cerebellum, Exp. Brain Res., 82, 547, 10.1007/BF00228796