Komplementärmedizin und assistierte Reproduktion

Gynäkologische Endokrinologie - Tập 7 - Trang 57-62 - 2009
A. Costea1, K. Münstedt1
1Zentrum für Frauenheilkunde & Geburtshilfe, Universitätsklinikum Giessen und Marburg GmbH, Gießen, Deutschland

Tóm tắt

Infertilität stellt ein uraltes menschliches Problem dar, das zu jeder Zeit mit allen verfügbaren Möglichkeiten der Zeit angegangen wurde. Da auch moderne Behandlungsmethoden nicht unbedingt erfolgreich sind, wenden bis zu 66% der Betroffenen Methoden der komplementären und alternativen Medizin (KAM) an. Vor diesem Hintergrund wird die Bedeutung von KAM derzeit sicher unterschätzt. Trotz der unzureichenden Datenlage erscheinen eine psychologische Betreuung und diätische Beratung als sinnvoll. Interessante phytotherapeutische Maßnahmen (Cimicifuga, Vitex agnus castus) sollten zukünftig näher untersucht werden. Therapieangebote aus dem Bereich der traditionellen chinesischen Medizin (Akupunktur, Moxibustion, TCM-Phytotherapie) haben bisher nicht überzeugt bzw. sind pharmazeutisch nicht als sicher zu betrachten (Schwermetallbelastung, undeklarierte Zusätze). Aufgrund der Prävalenz und der Möglichkeit der Verbesserung der Effizienz der Reproduktionsmedizin erscheint eine intensivere wissenschaftliche Auseinandersetzung mit dem Thema wichtig.

Tài liệu tham khảo

Abdelhafiz AT, Muhamad JA (2008) Midcycle pericoital intravaginal bee honey and royal jelly for male factor infertility. Int J Gynaecol Obstet 101:146–149 Anderson BJ, Haimovici F, Ginsburg ES et al (2007) In vitro fertilization and acupuncture: clinical efficacy and mechanistic basis. Altern Ther Health Med 13:38–48 Bergmann J, Luft B, Boehmann S et al (2000) Die Wirksamkeit des Komplexmittels Phyto-Hypophyson® L bei weiblicher, hormonell bedingter Sterilität. Eine randomisierte, placebokontrollierte, klinische Doppelblindstudie. Forsch Komplementarmed 7:190–199 Chen Z, Yin CP, Liu JH et al (2007) Extract on acanthopanacis senticosus improves sperm motility of asthenospermia patients in vitro. Zhonghua Nan Ke Xue 13:21–23 Cheong YC, Hung Yu Ng E, Ledger WL (2008) Acupuncture and assisted conception. Cochrane Database Syst Rev (4):CD006920 Comhaire FH, Garem YE, Mahmoud A et al (2005) Combined conventional/antioxidant „Astaxanthin“ treatment for male infertility: a double blind, randomized trial. Asian J Androl 7:257–262 Coulson C, Jenkins J (2005) Complementary and alternative medicine utilisation in NHS and private clinic settings: a United Kingdom survey of 400 infertility patients. J Exp Clin Assist Reprod 2:5 Coyle ME, Smith CA, Peat B (2005) Cephalic version by moxibustion for breech presentation. Cochrane Database Syst Rev 18(2):CD003928 Czeizel AE (1998) Periconceptional folic acid containing multivitamin supplementation. Eur J Obstet Gynecol Reprod Biol 78:151–161 Domar AD, Meshay I, Kelliher J et al (2009) The impact of acupuncture on in vitro fertilization outcome. Fertil Steril 91:723–726 Domar AD, Friedman R, Zuttermeister PC (1999) Distress and conception in infertile women: a complementary approach. J Am Med Womens Assoc 54:196–198 El-Toukhy T, Sunkara SK, Khairy M et al (2008) A systematic review and meta-analysis of acupuncture in in vitro fertilization. Int J Obstet Gynaecol 115:1203–1213 Ernst E (2002) Toxic heavy metals and undeclared drugs in Asian herbal medicine. Trends Pharmacol Sci 23:136–139 Ernst E (2002) Adulteration of Chinese herbal medicines with synthetic drugs: a systematic review. J Intern Med 252:107–113 Ernst E (2003) Serious psychiatric and neurological adverse effects of herbal medicines – a systematic review. Acta Psychiatr Scand 108:83–91 Eskenazi B, Kidd SA, Marks AR et al (2005) Antioxidant intake is associated with semen quality in healthy men. Hum Reprod 20:1006–1012 Gerhard I, Patek A, Monga B et al (1998) Mastodynon(R) bei weiblicher Sterilität. Forsch Komplementarmed 5:272–278 Heidary M, Reza Nejadi J, Delfan B et al (2008) Effect of saffron on semen parameters of infertile men. Urol J 5:255–259 Huang ST, Chen AP (2008) Traditional chinese medicine and infertility. Curr Opin Obstet Gynecol 20:211–215 Levitas E, Parmet A, Lunenfeld E et al (2006) Impact of hypnosis during embryo transfer on the outcome of in vitro fertilization-embryo transfer: a case-control study. Fertil Steril 85:1404–1408 Lian F, Teng YL, Zhang JW (2007) Clinical study on effect of Erzhi Tiangui Granule in improving the quality of oocytes and leukemia inhibitory factor in follicular fluid of women undergoing in vitro fertilization and embryo transfer. Zhongguo Zhong Xi Yi Jie He Za Zhi 27:976–979 Liu J, Liang P, Yin C et al (2004) Effects of several herbal aqueous extracts on human sperm motility in vitro. Andrologia 36:78–83 Manheimer E, Zhang G, Udoff L et al (2008) Effects of acupuncture on rates of pregnancy and live birth among women undergoing in vitro fertilisation: systematic review and meta-analysis. BMJ 336:545–549 Ng EH, So WS, Gao J et al (2008) The role of acupuncture in the management of subfertility. Fertil Steril 90:1–13 Rolf C, Cooper TG, Yeung CH, Nieschlag E (1999) Antioxidant treatment of patients with asthenozoospermia or moderate oligoasthenozoospermia with high-dose vitamin C and vitamin E: a randomized, placebo-controlled, double-blind study. Hum Reprod14:1028–1033 Shahin AY, Ismail AM, Zahran KM, Makhlouf AM (2008) Adding phytoestrogens to clomiphene induction in unexplained infertility patients – a randomized trial. Reprod Biomed Online 16:580–588 So EW, Ng EH, Wong YY et al (2008) A randomized double blind comparison of real and placebo acupuncture in IVF treatment. Hum Reprod 24:1–8 Song FJ, Zheng SL, Ma DZ (2008) Clinical observation on acupuncture for treatment of infertility of ovulatory disturbance. Zongguo Zhen Jiu 28:21–23 Stankiewicz M, Smith C, Alvino H, Norman R (2007) The use of complementary medicine and therapies by patients attending a reproductive medicine unit in South Australia: a prospective survey. Aust N Z J Obstet Gynaecol 47:145–149 Tremellen K, Miari G, Froiland D, Thompson J (2007) A randomised control trial examining the effect of an antioxidant (Menevit) on pregnancy outcome during IVF-ICSI treatment Aust N Z J Obstet Gynaecol 47:216–221 Westphal LM, Polan ML, Trant AS (2006) Double-blind, placebo-controlled study of Fertilityblend: a nutritional supplement for improving fertility in women. Clin Exp Obstet Gynecol 33:205–208 Yang CC, Chen JC, Chen GW et al (2003) Effects of Shao-Fu-Zhu-Yu-Tang on motility of human sperm. Am J Chin Med 31:573–579 Yang GY, Wang PJ, Jia XB (2001) Effect of bushen huoxue decoction on in vitro fertilization and early embryonic development in mice. Zhongguo Zhong Xi Yi Jie He Za Zhi 21:522–524 Zain MM, Norman RJ (2008) Impact of obesity on female fertility and fertility treatment. Womens Health 4:183–194 Zhang HQ, Yan B, Zhao HX et al (2006) Effect of traditional Chinese herbs combined with low dose human menopausal gonadotropin applied in frozen-thawed embryo transfer. Chin J Integr Med 12:244–249 Zhang HQ, Zhao HX, Zhang AJ (2007) Male infertility with severe oligospermatism and azoospermia trated by Bushen Shengjing Decoction combined with intracytoplasmic sperm injection. Zhongguo Zhong Xi Yi Jie He Za Zhi 27:972–975