Phenotyping of Aggressive Behavior in Golden Retriever Dogs with a Questionnaire
Tóm tắt
Reliable and valid phenotyping is crucial for our study of genetic factors underlying aggression in Golden Retriever dogs. A mail questionnaire based on the Canine Behavioral Assessment and Research Questionnaire (CBARQ; Hsu and Serpell, 2003, JAVMA 223(9):1293–1300) was used to assess behavioral phenotypes. Owners of 228 Golden Retrievers completed the questionnaire. These dogs had been referred to our clinic for aggression problems several years earlier or they were related to aggressive dogs. In this paper, three sets of results are presented, which indicate that behavior scores from the CBARQ can be applied to genetic studies. First, factor analysis demonstrated that CBARQ items can be grouped into 10 behavioral traits, including three types of aggression: stranger-directed aggression, owner-directed aggression, and dog-directed aggression. The results were remarkably similar to those reported by Hsu and Serpell. The aggression scores showed considerable variation in our dog families, which is a prerequisite for genetic studies. Second, retrospective questions enabled us to study changes in the aggressive behavior of the dogs in the course of time. After an average time interval of 4.3 years, over 50% of the dogs had become less aggressive. Third, we analyzed data obtained with an aggression test of 83 dogs. Two out of the three CBARQ aggression factors were also found in the aggression test data.
Tài liệu tham khảo
Bartels M, Hudziak JJ, van den Oord EJ, van Beijsterveldt CE, Rietveld MJ, Boomsma DI (2003) Co-occurence of aggressive behavior and rule-breaking behavior at age 12: multi-rater analyses. Behav Genet 33:607–621
Beaver BV (1993) Profiles of dogs presented for aggression. J Am Anim Hosp Assoc 29:564–569
Borchelt PL (1983) Aggressive behavior of dogs kept as companion animals: classification and influence of sex, reproductive status and breed. Appl Anim Ethol 10:45–61
Borchelt PL, Voith VL (1996) Aggressive behavior in dogs and cats. In: Voith VL, Borchelt PL (eds) Readings in companion animal behavior. Veterinary learning systems, Trenton, New Jersey, pp 217–229
Clutton-Brock J (1995) Origins of the dog: domestication and early history. In: Serpell J (ed) The domestic dog-its evolution, behaviour and interactions with people. Cambridge University Press, Cambridge, pp 8–20
Edwards RA (1991) Agression in Golden Retrievers. Vet Rec 27:410
Galac S, Knol BW (1997) Fear-motivated aggression in dogs: patient characteristics, diagnosis and therapy. Anim Welfare 6:9–15
Goodloe LP, Borchelt PL (1998) Companion dog temperament traits. J Appl Anim Welfare Sci 1:303–338
Gosling SD, Kwan VS, John OP (2003) A dog’s got personality: a cross-species comparative approach to personality judgments in dogs and humans. J Pers Soc Psychol 85:1161–1169
Hochberg Y (1988) A sharper Bonferonni procedure for multiple tests of significance. Biometrika 75:800–802
Heath S (1991) Aggression in Golden Retrievers. Vet Rec 11:459
Hsu Y, Serpell JA (2003) Development and validation of a questionnaire for measuring behavior and temperament traits in pet dogs. J Am Vet Med Assoc 223:1293–1300
Knol BW, Groenewoud-Jelsma HJC, Ubbink GJ (1997) Fear-motivated aggression in Golden Retrievers: no correlation with inbreeding. In: Proceedings of the first international conference on veterinary behavioural medicine, Birmingham, UK, p 112
Knol BW, Schilder MBH (1999) Onvoorspelbare agressie bij Golden Retrievers: een erfelijk probleem? Tijdschr Diergeneeskd 124:577–578
Landsberg G, Hunthausen W, Ackerman L (2004) Canine aggression. In: Landsberg G, Hunthausen W, Ackerman L (eds) Handbook of behavior problems of the dog and cat. Saunders, Edinburgh etc., pp 385–426
Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas III EJ, Zody MC, et al (2005) Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 438:803–819
Mathiowetz NA (2000) The effect of length of recall on the quality of survey data. In: Proceedings of the fourth conference on methodological issues in official statistics. Stockholm, Sweden, pp 1–8
Moon-Fanelli AA, Dodman NH (1998) Description and development of compulsive tail chasing in terriers and response to clomipramine treatment. J Am Vet Med Assoc 212:1252–1257
Moon-Fanelli AA (2002) Compulsive tail chasing in Bull Terriers. In: Proceedings of Advances in canine and feline genomics, St. Louis, USA
Mugford RA (1984) Behaviour problems in the dog. In: Anderson RS (ed) Nutrition and behaviour in dogs and cats. Pergamon Press, Oxford, pp 207–215
Overall KL (1997) Canine aggression. In: Overall KL (eds) Clinical behavioral medicine for small animals, Mosby, St. Louis, pp 88–129
Overall KL (2000) Natural animal models of human psychiatric conditions: assessment of mechanism and validity. Prog. Neuropsychopharmacol. Biol Psychiatry 24:727–776
Parker HG, Kim LV, Sutter NB, Carlson S, Lorentzen TD, Malek TB, Johnson GS, DeFrance HB, Ostrander EA, Kruglyak L (2004) Genetic structure of the purebred domestic dog. Science 304:1160–1164
Podberscek AL, Serpell JA (1996) The English Cocker Spaniel: preliminary findings on aggressive behaviour. Appl Anim Behav Sci 47:75–89
Reisner IR (1997) Assessment, management, and prognosis of canine dominance-related aggression. Vet Clin North Am Small Anim Pract 27:479–495
Reisner IR (2003) Differential diagnosis and management of human-directed aggression in dogs. Vet Clin North Am Small Anim Pract 33:303–320
Reisner IR, Houpt KA, Shofer FS (2005) National survey of owner-directed aggression in English Springer Spaniels. J Am Vet Med Assoc 227:1594–1603
Serpell JA, Hsu Y (2001) Development and validation of a novel method for evaluating behavior and temperament in guide dogs. Appl Anim Beh Sci 72:347–364
Svartberg K (2005) A comparison of behaviour in test and in everyday life: evidence of three consistent boldness-related personality traits in dogs. Appl Anim Beh Sci 91:103–128
Tabachnick BG, Fidell LS (2001) Using multivariate statistics. Allyn and Bacon, Boston
Tate RL, Wongbundhit Y (1983) Random versus nonrandom coefficient models for multilevel analysis. J Educat Statist 8:103–120
van den Berg L, Schilder MBH, Knol BW (2003a) Behavior genetics of canine aggression: behavioral phenotyping of golden retrievers by means of an aggression test. Behav Genet 33:469–483
van den Berg L, Versteeg SA, van Oost BA (2003b) Isolation and characterization of the canine serotonin receptor 1A gene (htr1A). J Hered 94:49–56
van den Berg L, Imholz S, Versteeg SA, Leegwater PAJ, Zijlstra C, Bosma AA, van Oost BA (2004) Isolation and characterization of the canine serotonin receptor 1B gene (htr1B). Gene 326:131–139
van den Berg L, Kwant L, Hestand MS, van Oost BA, Leegwater PAJ (2005) Structure and variation of three canine genes involved in serotonin binding and transport: the serotonin receptor 1A gene (htr1A), serotonin receptor 2A gene (htr2A), and serotonin transporter gene (slc6A4). J. Hered 96: 786–796
Winkler WG (1977) Human deaths induced by dog bites, United States, 1974–75. Public Health Rep 92:425–429
Wright JC (1985) Severe attacks by dogs: characteristics of the dogs, the victims, and the attack settings. Public Health Rep 100:55–61