Prevalence of dementia in a southern European population in two different time periods: the ZARADEMP Project

Acta Psychiatrica Scandinavica - Tập 116 Số 4 - Trang 299-307 - 2007
António Lobo1, P. Saz1, Gerardo Rojo-Marcos2, José Luis Día3, Concepción De‐la‐Cámara1, T. Ventura3, José Ángel Montañés1, Antonio Lobo-Escolar1, Sergio Nasarre Aznar1
1Departments of Psychiatry
2Preventive Medicine, Hospital Clínico Universitario
3Department of Psychiatry, Hospital Universitario Miguel Servet, Instituto Aragonés de Ciencias de la Salud, University of Zaragoza, Zaragoza, Spain

Tóm tắt

Objective:  To compare the prevalence of dementia in two different time periods and two different studies.Method:  Representative, random samples of the elderly (>65 years) in the Zaragoza Study or ZARADEMP‐0 (n = 1080) completed the previous decade, and now in Wave I of the ZARADEMP Project or ZARADEMP‐I (n = 3715) were interviewed. Standardized measures included the Geriatric Mental State and the History and Aetiology schedule. Cases of dementia were diagnosed according to DSM‐IV criteria.Results:  Adjusted, global prevalence of dementia has not varied significantly: it was 5.2% (95% CI = 3.9–6.6) in ZARADEMP‐0 and 3.9% (95% CI = 3.3–4.5) in ZARADEMP‐I (prevalence ratio = 0.75; 95% CI = 0.56–1.02). However, the prevalence in ZARADEMP‐I was significantly lower among men, particularly in all age groups between 70 and 84 years.Conclusion:  Stability of the global prevalence of dementia in the elderly population has been documented. However, the decreased prevalence found in elderly men stimulated environmental hypotheses.

Từ khóa


Tài liệu tham khảo

10.1787/485700737071

10.1111/j.1600-0447.2005.00632.x

10.1212/WNL.43.10.1887

10.1111/j.1600-0447.1987.tb02906.x

10.1093/ije/20.3.736

Lobo A, 2000, Prevalence of dementia and major 8 subtypes in Europe: a collaborative study of population‐based cohorts, Neurology, 54, S4

Fratiglioni L, 2000, Incidence of dementia and major subtypes in Europe: a collaborative study of population‐based cohorts. Neurologic Diseases in the Elderly Research Group, Neurology, 54, S10

10.1001/archpsyc.1995.03950180083011

Rocca AW, 2000, Dementia, Parkinson's disease, and stroke in Europe: a commentary, Neurology, 54, S38

Lobo A, 2005, The Zarademp‐Project on the incidence, prevalence and risk factors of dementia (and depression) in the elderly community: II. Methods and first results, Eur J Psychiatry, 19, 40

10.4321/S0213-61632005000200006

10.1016/0022-3956(75)90026-6

Lobo A, 1999, [Revalidation and standardization of the cognition mini‐exam (first Spanish version of the Mini‐Mental Status Examination) in the general geriatric population], Med Clin (Barc), 112, 767

10.1017/S0033291700015889

10.1192/bjp.150.6.815

10.1002/(SICI)1099-1166(199608)11:8<721::AID-GPS358>3.0.CO;2-R

10.1192/bjp.161.2.230

10.1002/gps.930070610

10.1111/j.1532-5415.2007.01590.x

10.1001/jama.1963.03060120024016

Tárraga LL, 1995, El médico ante la demencia y su entorno, 37

ÁLvarez M, 1992, Capacidad funcional de pacientes mayores de 65 años, según el Índice de Katz. Fiabilidad del método, Aten Primaria, 10, 812

10.1093/geronj/46.4.M132

Instituto Aragonés de Estadística, 2006, IAEST Datos básicos

Gardner MJ, 1989, Statistics with confidence, 61

Statistical Office of the European Communities, 1999, Eurostat: statistical information service, data shop network, 1992 (online)

10.1093/ije/27.1.91

Agresti A, 1990, Categorical data analysis, 13

Schiaffino A, 2003, Odds ratio or prevalence ratio? Their use in cross‐sectional studies, Gac Sanit, 17, 70

10.1097/00001504-199503000-00011

10.1016/j.biopsych.2005.02.004

10.1176/ps.50.9.1158

10.1176/appi.ajgp.13.8.656

10.1046/j.1600-0447.2003.00260.x

Instituto Nacional de Estadística, 2006, Encuesta nacional de Salud. Ministerio de Sanidad y Consumo

Pyles RB, 2001, The association of herpes simplex virus and Alzheimer's disease: a potential synthesis of genetic and environmental factors, Herpes, 8, 64

10.1046/j.1468-1331.2003.00779.x

10.1016/S0197-4580(02)00078-7

Cabre I, Envejecimiento demográfico en España

10.7326/0003-4819-131-3-199908030-00002

10.1037/0022-006X.58.3.323

10.1007/s001270050068

10.1136/bmj.1.4093.1217

10.1192/bjp.179.3.255