Risk factors for cutaneous malignant melanoma in a northern italian population

International Journal of Cancer - Tập 39 Số 2 - Trang 150-154 - 1987
Mario Cristofolini1, Laura Tasin1, Giuseppe Zumiani2, Silvia Franceschi1, Renato Talamini3, Francesco Piscioli4, Carlo La Vecchia5
1St. Chiara Hospital
2Department of Dermatology, S. Chiara Hospital, Trento
3Centro di Riferimento Oncologico
4Department of Pathology, S. Chiara Hospital, Trento
5“Mario Negri” Institute for Pharmacological Research, Milan, Italy

Tóm tắt

AbstractThe relationship between cutaneous malignant melanoma (CMM) and the colour of skin, hair and eyes, the extent of sun exposure and reaction to it, education, and the occurrence of skin neoplasms in patients and their families was evaluated in a case‐control study of 103 cases of CMM and 205 control subjects hospitalized for acute conditions other than malignant or hormonal disease. A significantly higher risk was associated with fair skin as compared to dark/medium skin (RR = 4.0; 95% CI: 1.5‐10.5) and positive family history for CMM (RR = 8.1; 95% CI: 1.0‐200.9). CMM seemed to occur more frequently, but not significantly so, in individuals with brown or blond hair, higher education and clinically diagnosed dysplastic naevi. Outdoor occupation and heavy sun exposure in the last 20 years seemed to increase the risk of CMM in sunexposed sites but to be negatively associated with CMM in normally unexposed sites.

Từ khóa


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Thông tin
Thông tin xuất bản

International Journal of Cancer

Tập 39 Số 2

150-154

Thông tin tác giả