Effect of purified zona antibody on fertilization in the mouse

Wiley - Tập 217 Số 1 - Trang 103-108 - 1981
Y. Tsunoda1, T. Sugie1, Junichi Mori1, S. Isojima2, K. Koyama2
1National Institute of Animal Industry, Tsukuba Norindanchi, P.O. Box 5, Ibaraki 305, Japan
2Hyogo Medical College, Nishinomiyashi, 663 Japan

Tóm tắt

AbstractBivalent (IgG) rabbit anti‐mouse zona pellucida antibody completely inhibited fertilization in the mouse. Univalent (Fab) zona antibody did not inhibit the fertilizability of eggs. However, the treatment or injection with anti‐rabbit IgG serum inhibited the fertilizability of eggs pretreated with antiserum Fab or eggs from females injected with antiserum Fab. It is concluded that the inhibition of fertilization by bivalent mouse zona antibody depends on the possibility that the antisera are directed against the zona as a whole and not specifically against the receptors for the Sperm.

Từ khóa


Tài liệu tham khảo

10.1111/j.1440-169X.1967.tb00227.x

10.1016/0014-4827(73)90317-0

10.1016/0014-4827(72)90258-3

10.3109/08820137609033855

10.1007/978-1-4615-8804-7

10.1530/jrf.0.0490055

10.1016/S0015-0282(16)42744-5

10.1016/0014-4827(67)90192-9

Metz C. B., 1972, Effects of antibodies on gamets and fertilization, Biol. Reprod., 6, 358, 10.1093/biolreprod/6.3.358

10.1111/j.1440-169X.1972.00207.x

10.1042/bj0730119

10.1530/jrf.0.0560533

10.3181/00379727-110-27525

Sober H. A., 1958, Protein chroma tography on ion exchange cellulose, Fed. Proc., 17, 1116

Toyoda Y., 1971, Studies on the fertilization of mouse eggs in vitro. I. In vitro fertilization of eggs by fresh epididymal sperm, Japanese J. Anim. Reprod., 16, 147, 10.1262/jrd1955.16.147

10.1530/jrf.0.0360009

10.1530/jrf.0.0440139

10.1530/jrf.0.0540233

Tsunoda Y., 1977, Inhibition of fertilization in mice by anti‐zona pellucida antiserum, Jpn. J. Zootech. Sci., 48, 784

10.1095/biolreprod21.3.749

10.1002/jez.1402070214

Tsunoda Y., 1980, Inhibition of fertilization by zona pellucida antibody, Arch. Androl., 5, 58

Thông tin
Thông tin xuất bản

Wiley

Tập 217 Số 1

103-108

Thông tin tác giả