The hallucinogen d-lysergic acid diethylamide (d-LSD) induces the immediate-early gene c-Fos in rat forebrain

Brain Research - Tập 958 - Trang 251-260 - 2002
Paul S Frankel1, Kathryn A Cunningham1
1Department of Pharmacology and Toxicology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555-1031, USA

Tài liệu tham khảo

Abraham, 1996, The psychopharmacology of hallucinogens, Neuropsychopharmacology, 14, 285, 10.1016/0893-133X(95)00136-2 Adams, 1982, LSD-induced alterations of locomotor patterns and exploration in rats, Psychopharmacology, 77, 179, 10.1007/BF00431945 Adams, 1985, A proposed animals model for hallucinogens based on LSD’s effect on patterns of exploration in rats, Behav. Neurosci., 99, 881, 10.1037/0735-7044.99.5.881 Aghajanian, 1968, Lysergic acid diethylamide: sensitive neuronal units in the midbrain raphe, Science, 161, 706, 10.1126/science.161.3842.706 Aghajanian, 1999, Serotonin and hallucinogens, Neuropsychopharmacology, 21, 16S, 10.1038/sj.npp.1395318 Backstrom, 1999, Agonist-directed signaling of 5-HT2C receptors: differences between serotonin and lysergic acid diethylamide (LSD), Neuropsychopharmacology, 21, 77S Brown, 1998, A two focal plane method for digital quantification of nuclear immunoreactivity in large brain areas using NIH-Image software, Brain Res. Protocols, 2, 264, 10.1016/S1385-299X(98)00003-8 Callahan, 1997, Mediation of the discriminative stimulus properties of cocaine by mesocorticolimbic dopamine systems, Pharmacol. Biochem. Behav., 57, 601, 10.1016/S0091-3057(96)00434-0 Ceccatelli, 1989, Expression of c-Fos immunoreactivity in transmitter-characterized neurons after stress, Proc Natl. Acad. Sci. USA, 86, 9569, 10.1073/pnas.86.23.9569 Clemett, 2000, Immunohistochemical localization of the 5-HT2C receptor protein in the rat CNS, Neuropharmacolgy, 39, 123, 10.1016/S0028-3908(99)00086-6 Cohen, 1978, Psychotomimetics (hallucinogens) and cannabis, 357 Colpaert, 1982, A drug discrimination analysis of lysergic acid diethylamide: in vivo agonist and antagonist effects of purported 5-hydroxytryptamine antagonists and of pirenpirone, an LSD-antagonist, J. Pharmacol. Exp. Ther., 221, 206 Colpaert, 1985, Behavioral and 5-HT antagonist effects of ritanserin: a pure and selective antagonist of LSD discrimination in rat, Psychopharmacology, 86, 45, 10.1007/BF00431683 Cornea-Hebert, 1999, Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat, J. Comp. Neurol., 409, 187, 10.1002/(SICI)1096-9861(19990628)409:2<187::AID-CNE2>3.0.CO;2-P Cullian, 1995, Pattern and time course of immediate-early gene expression in rat brain following acute stress, Neuroscience, 64, 477, 10.1016/0306-4522(94)00355-9 Cunningham, 1987, Neuropharmacological reassessment of the discriminative stimulus properties of d-lysergic acid diethylamide (LSD), Psychopharmacology, 91, 67, 10.1007/BF00690929 Delfs, 1990, Microinjection of cocaine into the nucleus accumbens elicits locomotor activation in the rat, J. Neurosci., 10, 303, 10.1523/JNEUROSCI.10-01-00303.1990 Devinsky, 1995, Contributions of anterior cingulated cortex to behavior, Brain, 118, 279, 10.1093/brain/118.1.279 Dolphin, 1978, Direct interaction of LSD with central ‘beta’-adrenergic receptors, Life Sci., 22, 345, 10.1016/0024-3205(78)90142-X Duncan, 1996, Neuroanatomical characterization of Fos induction in rat behavioral models of anxiety, Brain Res., 713, 79, 10.1016/0006-8993(95)01486-1 Duxon, 1997, Evidence for expression of the 5-hydroxytryptamine-2B receptor protein in the rat central nervous system, Neuroscience, 76, 323, 10.1016/S0306-4522(96)00480-0 Egan, 1998, Agonist activity of LSD and lisuride at cloned 5-HT2A and 5-HT2C receptors, Psychopharmacology, 136, 409, 10.1007/s002130050585 Erdtmann-Vourliotis, 1999, Acute injection of drugs with low addictive potential (Δ9-tetrahydrocannabinol, 3,4-methylenedioxymethamphetamine, lysergic acid diamide) causes a much higher c-fos expression in limbic brain areas than highly addicting drugs (cocaine and morphine), Mol. Brain Res., 71, 313, 10.1016/S0169-328X(99)00207-7 Erdtmann-Vourliotis, 2000, Prior experience of morphine application alters the c-fos response to MDMA (‘ecstasy’) and cocaine in the rat striatum, Mol. Brain Res., 77, 55, 10.1016/S0169-328X(00)00040-1 Frankel, 2001, Modulation of d-lysergic acid diethylamide (LSD) evoked hypoactivity and c-Fos expression by 5-HT2 receptors antagonists, Abstr. Soc. Neurosci., 31, 221.15 Frankel, 1999, Chronic administration of morphine alters immediate-early gene expression in the forebrain of post-dependent rats, Brain Res., 835, 204, 10.1016/S0006-8993(99)01579-6 Freedman, 1986, Hallucinogen drug research—if so, so what? Symposium summary and commentary, Pharmacol. Biochem. Behav., 24, 407, 10.1016/0091-3057(86)90371-0 Gaddum, 1953, Antagonism between lysergic acid diethylamide and 5-hydroxytryptamine, J. Physiol., 121, 15P Giacomelli, 1998, Lysergic acid diethylamide (LSD) is a partial agonist of D2 dopaminergic receptors and it potentiates dopamine-mediated prolactin secretion in lactrotrophs in vitro, Life Sci., 63, 215, 10.1016/S0024-3205(98)00262-8 Glennon, 1984, Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents, Life Sci., 35, 2505, 10.1016/0024-3205(84)90436-3 Green, 1978, Defining the histamine H2-receptor in brain: the interaction with LSD, NIDA Res. Monogr., 22, 38 Gresch, 2000, LSD-induced c-fos expression in rat brain: role of serotonin-2A and serotonin-2C receptors, Abstr. Soc. Neurosci., 30, 46.15 Gresch, 2002, Lysergic acid diethylamide-induced fos expression in rat brain: role of serotonin-2A receptors, Neuroscience, 114, 707, 10.1016/S0306-4522(02)00349-4 Harlan, 1998, Drugs of abuse and immediate early genes in the forebrain, Mol. Neurobiol., 16, 221, 10.1007/BF02741385 Heimer, 1997, The accumbens: beyond the core-shell dichotomy, J. Neuropsychiatry Clin. Neurosci., 9, 354, 10.1176/jnp.9.3.354 Heimer, 1997, Olmos, Substantia innominata: a notion which impedes clinical-anatomical correlations in neuropsychiatric disorders, Neuroscience, 76, 957, 10.1016/S0306-4522(96)00405-8 Herdegen, 1998, Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins, Brain Res. Rev., 28, 370, 10.1016/S0165-0173(98)00018-6 Hughes, 1995, Induction of immediate early genes and the control of neurotransmitter-regulated gene expression within the nervous system, Pharmacol. Rev., 47, 133 Ideker, 2001, Integrated genomic and protemic analyses of a systemically perturbed metabolic network, Science, 292, 929, 10.1126/science.292.5518.929 Jacobs, 1976, An animal model for studying central serotonergic synapses, Life Sci., 19, 777, 10.1016/0024-3205(76)90303-9 Jakob, 1998, 5-HT2A serotonin receptors in primate cerebral cortex: possible site of action of hallucinogens in pyramidal cell apical dendrites, Proc. Natl. Acad. Sci. USA, 95, 735, 10.1073/pnas.95.2.735 Krebs-Thomson, 1998, Effects of hallucinogens on locomotor and investigatory activity and patterns: influence of 5-HT2A and 5-HT2C receptors, Neuropsychopharmacology, 18, 339, 10.1016/S0893-133X(97)00164-4 Luiten, 1987, The hypothalamus, intrinsic connections and outflow pathways to the endocrine system in relation to the control of feeding and metabolism, Prog. Neurobiol., 28, 1, 10.1016/0301-0082(87)90004-9 Marek, 1996, LSD and the phenethylamine DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex, J. Pharmacol. Exp. Ther., 278, 1372 Marek, 1998, Indolamine and the phenethylamine hallucinogens: mechanisms of psychotomimetic action, Drug Alcohol Depend., 51, 189, 10.1016/S0376-8716(98)00076-3 Mackowiak, 1999, c-Fos proteins, induced by the serotonin receptor agonist doi, are not expressed in 5-HT2A positive cortical neurons, Mol. Brain Res., 71, 358, 10.1016/S0169-328X(99)00195-3 McGeorge, 1989, The organization of the projection from the cerebral cortex to the striatum of the rat, Neuroscience, 29, 503, 10.1016/0306-4522(89)90128-0 McKinzie, 1999, Cocaine is self-administered into the shell region of the nucleus accumbens in Wistar rats, Ann. NY Acad. Sci., 877, 788, 10.1111/j.1749-6632.1999.tb09323.x McKitrick, 2000, Expression of Fos in the hypothalamus of rats exposed to warm and cold temperatures, Brain Res. Bull., 53, 307, 10.1016/S0361-9230(00)00346-4 Mijnster, 1997, Regional and cellular distribution of serotonin 5-hydroxytryptamine2a receptor mRNA in the nucleus accumbens, olfactory tubercle, and caudate putamen of the rat, J. Comp. Neurol., 389, 1, 10.1002/(SICI)1096-9861(19971208)389:1<1::AID-CNE1>3.0.CO;2-6 Million, 2000, Differential fos expression in the paraventricular nucleus of the hypothalamus, sacral parasympathetic nucleus and colonic motor response to water avoidance stress in Fischer and Lewis strain rats, Brain Res., 877, 345, 10.1016/S0006-8993(00)02719-0 Minnema, 1980, LSD as a discriminative stimulus: role of dorsal raphe nucleus, Subst. Alcohol Actions/Misuse, 1, 29 Morgan, 1987, Mapping pattern of c-fos expression in the central nervous system after seizure, Science, 237, 192, 10.1126/science.3037702 Morgan, 1991, Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun, Annu. Rev. Neurosci., 14, 421, 10.1146/annurev.ne.14.030191.002225 B Nielsen, 1985, Antagonism of the LSD cue by putative serotonin antagonists; relationships to inhibition of in vivo 3H-spiroperidol binding, Behav. Brain Res., 16, 171, 10.1016/0166-4328(85)90090-7 Nielsen, 1986, Cueing effects of amphetamine and LSD: elicitation by direct microinjection of the drugs into the nucleus accumbens, Eur. J. Pharmacol., 125, 85, 10.1016/0014-2999(86)90086-5 Paxinos, 1998 Persico, 1993, Brain transcription factor expression: effects of acute and chronic amphetamine and injection stress, Mol. Brain Res., 20, 91, 10.1016/0169-328X(93)90113-4 Sager, 1988, Expression of c-fos protein in brain: metabolic mapping at the cellular level, Science, 240, 1417 Scruggs, 2000, DOI-induced activation of the cortex: dependence on 5-HT2A heteroreceptors on thalamocortical glutamatergic neurons, J. Neurosci., 20, 8846, 10.1523/JNEUROSCI.20-23-08846.2000 Sharma, 1997, Distribution of the 5-HT2C receptor protein in adult rat brain and spinal cord determined using a receptor-directed antibody: effect of 5,7-dihydroxytryptamine, Synapse, 27, 45, 10.1002/(SICI)1098-2396(199709)27:1<45::AID-SYN5>3.0.CO;2-D Shaw, 1956, Some serotoninlike activities of lysergic acid diethylamide, Science, 124, 121, 10.1126/science.124.3212.121 Silbergeld, 1979, Lisuride and LSD: dopaminergic and serotonergic interactions in the ‘serotonin syndrome’, Pyschopharmacology, 65, 233, 10.1007/BF00492209 Sprouse, 1987, Electrophysiological responses to serotonergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists, Synapse, 1, 3, 10.1002/syn.890010103 Strassman, 1984, Adverse reactions to psychedelic drugs: a review of the literature, J. Nerv. Ment. Dis., 172, 577, 10.1097/00005053-198410000-00001 Tanji, 2001, Behavioral planning in the prefrontal cortex, Curr. Opin. Neurobiol., 11, 164, 10.1016/S0959-4388(00)00192-6 Tzschentke, 2001, Pharmacology and behavioral pharmacology of the mesocortical dopamine system, Prog. Neurobiol., 63, 241, 10.1016/S0301-0082(00)00033-2 Watts, 1995, LSD and structural analogues: pharmacological evaluation at D1 dopamine receptors, Psychopharmacology, 118, 401, 10.1007/BF02245940 Wellman, 1993, Modulation of feeding by hypothalamic paraventricular nucleus a1- and a2-adrenergic receptors, Life Sci., 53, 669, 10.1016/0024-3205(93)90243-V Wright, 1995, Comparative localization of serotonin 1A,1C and 2 receptor subtype mRNAs in rat brain, J. Comp. Neurol., 351, 357, 10.1002/cne.903510304 Zilles, 1995, Cortex: areal and laminar structure, 649