Computer mouse movement patterns: A potential marker of mild cognitive impairment

Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring - Tập 1 - Trang 472-480 - 2015
Adriana Seelye1,2, Stuart Hagler3, Nora Mattek1,2, Diane B. Howieson1, Katherine Wild1,2, Hiroko H. Dodge1,2, Jeffrey A. Kaye1,2,4
1Department of Neurology, Oregon Health & Science University, Portland, OR, USA
2Oregon Center for Aging and Technology, Oregon Health & Science University, Portland, OR, USA
3Northeastern University, Boston, MA, USA
4Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA

Tóm tắt

AbstractIntroductionSubtle changes in cognitively demanding activities occur in mild cognitive impairment (MCI) but are difficult to assess with conventional methods. In an exploratory study, we examined whether patterns of computer mouse movements obtained from routine home computer use discriminated between older adults with and without MCI.MethodsParticipants were 42 cognitively intact and 20 older adults with MCI enrolled in a longitudinal study of in‐home monitoring technologies. Mouse pointer movement variables were computed during one week of routine home computer use using algorithms that identified and characterized mouse movements within each computer use session.ResultsMCI was associated with making significantly fewer total mouse moves (P < .01) and making mouse movements that were more variable, less efficient, and with longer pauses between movements (P < .05). Mouse movement measures were significantly associated with several cognitive domains (P values <.01–.05).DiscussionRemotely monitored computer mouse movement patterns are a potential early marker of real‐world cognitive changes in MCI.

Tài liệu tham khảo

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Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring

Tập 1

472-480

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