Excess mortality of schizophrenia

British Journal of Psychiatry - Tập 171 Số 6 - Trang 502-508 - 1997
Steve Brown1
1Department of Psychiatry, University of Southampton, Royal South Hants Hospital.

Tóm tắt

BackgroundThis paper presents a structured review of the published information on the mortality of schizophrenia.MethodA meta-analysis of the literature.ResultsSchizophrenia has a significantly increased mortality from natural and unnatural causes. Twenty-eight percent of the excess mortality is attributable to suicide and 12% to accidents. The rest of the excess mortality is from the same broad range of conditions which cause deaths in the general population. Further interpretation is hampered by confounding variables, wide confidence intervals and reservations about generalising from individual cohorts.ConclusionsThe available evidence suggests that schizophrenia is associated with a large increased mortality from suicide and a moderate increased mortality from natural causes. A number of possible interventions have been identified, but we do not yet have reliable means of detecting any changes in mortality which might result.

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Thông tin xuất bản

British Journal of Psychiatry

Tập 171 Số 6

502-508

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