EANM guidelines for ventilation/perfusion scintigraphy

European Journal of Nuclear Medicine - Tập 36 - Trang 1528-1538 - 2009
M. Bajc1, J. B. Neilly2, M. Miniati3, C. Schuemichen4, M. Meignan5, B. Jonson1
1Department of Clinical Physiology, Lund University Hospital, Lund, Sweden
2University Medical Unit & Nuclear Medicine, Glasgow Royal Infirmary, Scotland, UK
3Department of Medical and Surgical Critical Care, University of Florence, Italy, Florence, Italy
4University Hospital Rostock, Clinic for Nuclear Medicine, Rostock, Germany
5Department of Nuclear Medicine, Centre Hospitalo Universitaire Henri Mondor, Université Paris 12, Créteil, France

Tóm tắt

As emphasized in Part 1 of these guidelines, the diagnosis of pulmonary embolism (PE) is confirmed or refuted using ventilation/perfusion scintigraphy (V/PSCAN) or multidetector computed tomography of the pulmonary arteries (MDCT). To reduce the costs, the risks associated with false-negative and false-positive diagnoses, and unnecessary radiation exposure, preimaging assessment of clinical probability is recommended. Diagnostic accuracy is approximately equal for MDCT and planar V/PSCAN and better for tomography (V/PSPECT). V/PSPECT is feasible in about 99% of patients, while MDCT is often contraindicated. As MDCT is more readily available, access to both techniques is vital for the diagnosis of PE. V/PSPECT gives an effective radiation dose of 1.2–2 mSv. For V/PSPECT, the effective dose is about 35–40% and the absorbed dose to the female breast 4% of the dose from MDCT performed with a dose-saving protocol. V/PSPECT is recommended as a first-line procedure in patients with suspected PE. It is particularly favoured in young patients, especially females, during pregnancy, and for follow-up and research.

Tài liệu tham khảo

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