Low toxicity and accumulation of zinc oxide nanoparticles in mice after 270-day consecutive dietary supplementation

Toxicology Research - Tập 6 Số 2 - Trang 134-143
Jiahui Liu1,2,3,4,5, Xin Ma4,6,7,8, Yingying Xu1,3,4,9,5, Huan Tang1,3,4,9,5, Sheng‐Tao Yang1,3,4,9,5, Yifan Yang4,6,7,8, Dongdong Kang4,6,7,8, Haifang Wang4,6,7,8, Yuanfang Liu1,3,4,9,5
1Beijing 100871
2Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China
3Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China
4China
5Peking University
6Institute of Nanochemistry and Nanobiology, Shanghai University, Shanghai 200444, China
7Shanghai 200444
8Shanghai University
9College of Chemistry and Molecular Engineering

Tóm tắt

After 270-day consecutive feeding with food containing ZnO nanoparticles, ZnO microparticles and Zn ions, no Zn level increase was found in any organ except digestive tract organs and only ZnO nanoparticles induce minor toxicity.

Từ khóa


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