Identifying chemogenetic interactions from CRISPR screens with drugZ

Medina Colic1, Gang Wang1, Michal Zimmermann2, Keith Mascall3, Megan McLaughlin1, Lori Bertolet1, Walter F. Lenoir4, Jason Moffat5, Stéphane Angers3, Daniel Durocher2, Traver Hart1
1Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
2Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada
3Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada
4UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
5Donnelly Centre, University of Toronto, Toronto, ON, Canada

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