A Phase I Trial of Intravenous CG7870, a Replication-Selective, Prostate-Specific Antigen–Targeted Oncolytic Adenovirus, for the Treatment of Hormone-Refractory, Metastatic Prostate Cancer

Molecular Therapy - Tập 14 - Trang 107-117 - 2006
Eric J. Small1, Michael A. Carducci2, James M. Burke3, Ron Rodriguez2, Lawrence Fong1, Lynn van Ummersen4, D.C. Yu3, Junko Aimi3, Dale Ando3, Peter Working3, David Kirn5, George Wilding4
1University of California, Comprehensive Cancer Center San Francisco, San Francisco, CA 94143, USA
2Prostate Cancer Program at the Kimmel Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA
3Cell Genesys, Inc., Division of Clinical Research, South San Francisco, CA 94080, USA
4Department of Medical Oncology, University of Wisconsin, WI 53705, USA
5Department of Pharmacology, Oxford University, OX2 6DP Oxford, UK

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