A convenient preparation of 10-hydroxydecanoic acid
Tóm tắt
The alkaline cleavage of ricinoleates may be carried out in ethanol at temperatures of 190–200 C using two to three equivalents of NaOH to give yields up to 69% of pure 10-hydroxydecanoic acid. This method avoids the use of large excesses of alkali as well as the use of high boiling alcohols as reaction media.
Tài liệu tham khảo
Ansell, M.F., and B.C.L. Weedon, Ind. Chemist 40(2):70 (1964).
Diamond, M.J., R.G. Binder and T.H. Applewhite, JAOCS 42:882 (1965).
Diamond, M.J., and T.H. Applewhite, Ibid. 44:656 (1967).
Lycan, W.H., and R. Adams, J. Am. Chem. Soc. 51:625 (1929).