Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers

Xu, 2007, Evolution of symbiotic bacteria in the distal human intestine, PLoS Biol, 5, e156, 10.1371/journal.pbio.0050156 Santacruz, 2009, Interplay between weight loss and gut microbiota composition in overweight adolescents, Obesity (Silver Spring), 17, 1906, 10.1038/oby.2009.112 Lee, 2006, Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota, Res Microbiol, 157, 876, 10.1016/j.resmic.2006.07.004 Hervert-Hernandez, 2011, Dietary polyphenols and human gut microbiota: a review, Food Rev Int, 27, 154, 10.1080/87559129.2010.535233 Clifford, 2004, Diet-derived phenols in plasma and tissues and their implications for health, Planta Med, 70, 1103, 10.1055/s-2004-835835 Manach, 2004, Polyphenols: food sources and bioavailability, Am J Clin Nutr, 79, 727, 10.1093/ajcn/79.5.727 Saura-Calixto, 2007, Intake and bioaccessibility of total polyphenols in a whole diet, Food Chem, 101, 492, 10.1016/j.foodchem.2006.02.006 Requena, 2010, Perspectives of the potential implications of wine polyphenols on human oral and gut microbiota, Trends Food Sci Technol, 21, 332, 10.1016/j.tifs.2010.04.004 Walle, 2011, Bioavailability of resveratrol, Ann N Y Acad Sci, 1215, 9, 10.1111/j.1749-6632.2010.05842.x Fernández-Mar, 2012, Bioactive compounds in wine: resveratrol, hydroxytyrosol and melatonin: a review, Food Chem, 130, 797, 10.1016/j.foodchem.2011.08.023 Azorín-Ortuño, 2011, Metabolites and tissue distribution of resveratrol in the pig, Mol Nutr Food Res, 55, 1154, 10.1002/mnfr.201100140 Jung, 2009, Interaction of dietary resveratrol with animal-associated bacteria, FEMS Microbiol Lett, 297, 266, 10.1111/j.1574-6968.2009.01691.x Rodríguez Vaquero, 2007, Antibacterial effect of phenolic compounds from different wines, Food Contr, 18, 93, 10.1016/j.foodcont.2005.08.010 Kemperman, 2010, Novel approaches for analysing gut microbes and dietary polyphenols: challenges and opportunities, Microbiology, 156, 3224, 10.1099/mic.0.042127-0 Selma, 2009, Interaction between phenolics and gut microbiota: role in human health, J Agric Food Chem, 57, 6485, 10.1021/jf902107d The Airlie (VA) Consensus Conference. In: Loham T, Roche A, Martorel R, eds. Standardization of anthropometric measurements. Champaign, IL: Human Kinetics, 1988:20–37 Zamora-Ros, 2006, Diagnostic performance of urinary resveratrol metabolites as a biomarker of moderate wine consumption, Clin Chem, 52, 1373, 10.1373/clinchem.2005.065870 Zamora-Ros, 2009, Resveratrol metabolites in urine as a biomarker of wine intake in free-living subjects: The PREDIMED Study, Free Radic Biol Med, 46, 1562, 10.1016/j.freeradbiomed.2008.12.023 Urpi-Sarda, 2007, HPLC-tandem mass spectrometric method to characterize resveratrol metabolism in humans, Clin Chem, 53, 292, 10.1373/clinchem.2006.071936 Juan, 2010, Determination of dihydroresveratrol in rat plasma by HPLC, J Agric Food Chem, 58, 7472, 10.1021/jf100836j Guo, 2008, Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs, Lett Appl Microbiol, 47, 367, 10.1111/j.1472-765X.2008.02408.x Delroisse, 2008, Quantification of Bifidobacterium spp. and Lactobacillus spp. in rat fecal samples by real-time PCR, Microbiol Res, 163, 663, 10.1016/j.micres.2006.09.004 Friswell, 2010, Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice, PLoS ONE, 5, e8584, 10.1371/journal.pone.0008584 Stach, 2003, New primers for the class Actinobacteria: application to marine and terrestrial environments, Environ Microbiol, 5, 828, 10.1046/j.1462-2920.2003.00483.x Matsuki, 2004, Use of 16S rRNA gene-targeted group-specific primers for real-time PCR analysis of predominant bacteria in human feces, Appl Environ Microbiol, 70, 7220, 10.1128/AEM.70.12.7220-7228.2004 Bekele, 2010, Genetic diversity and diet specificity of ruminal Prevotella revealed by 16S rRNA gene-based analysis, FEMS Microbiol Lett, 305, 49, 10.1111/j.1574-6968.2010.01911.x Rinttilä, 2004, Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR, J Appl Microbiol, 97, 1166, 10.1111/j.1365-2672.2004.02409.x Lau SK, Woo PC, Woo GK, Fung AM, Wong MK, Chan KM, Tam DM, Yuen KY. Eggerthella hongkongensis sp. nov. and Eggerthella sinensis sp. nov., two novel Eggerthella species, account for half of the cases of Eggerthella bacteremia. Diagn Microbiol Infect Dis 2004;49: 255–63. Liu, 2003, Rapid identification of the species of the Bacteroides fragilis group by multiplex PCR assays using group- and species-specific primers, FEMS Microbiol Lett, 222, 9, 10.1016/S0378-1097(03)00296-9 Ibern-Gomez, 2002, Rapid HPLC analysis of phenolic compounds in red wines, Am J Enol Vitic, 53, 218, 10.5344/ajev.2002.53.3.218 Romero-Pérez, 1999, Piceid, the major resveratrol derivative in grape juices, J Agric Food Chem, 47, 1533, 10.1021/jf981024g Singleton, 1965, Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents, Am J Enol Vitic, 16, 144, 10.5344/ajev.1965.16.3.144 Zoetendal, 1998, Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria, Appl Environ Microbiol, 64, 3854, 10.1128/AEM.64.10.3854-3859.1998 Vanhoutte, 2006, Molecular monitoring of the fecal microbiota of healthy human subjects during administration of lactulose and Saccharomyces boulardii, Appl Environ Microbiol, 72, 5990, 10.1128/AEM.00233-06 Tzounis, 2008, Flavanol monomer-induced changes to the human faecal microflora, Br J Nutr, 99, 782, 10.1017/S0007114507853384 Yamakoshi, 2001, Effect of proanthocyanidin-rich extract from grape seeds on human fecal flora and fecal odor, Microb Ecol Health Dis, 13, 25 Tzounis, 2011, Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, double-blind, crossover intervention study, Am J Clin Nutr, 93, 62, 10.3945/ajcn.110.000075 Smith, 2005, Bacterial mechanisms to overcome inhibitory effects of dietary tannins, Microb Ecol, 50, 197, 10.1007/s00248-004-0180-x Dolara, 2005, Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F344 rats, Mutat Res, 591, 237, 10.1016/j.mrfmmm.2005.04.022 Sirk, 2009, Molecular binding of catechins to biomembranes: relationship to biological activity, J Agric Food Chem, 57, 6720, 10.1021/jf900951w Smith, 2004, The effect of condensed tannins on bacterial diversity and metabolic activity in the rat gastrointestinal tract, Appl Environ Microbiol, 70, 1104, 10.1128/AEM.70.2.1104-1115.2004 Guarner, 2003, Gut flora in health and disease, Lancet, 361, 512, 10.1016/S0140-6736(03)12489-0 Stivala, 2001, Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol, J Biol Chem, 276, 22586, 10.1074/jbc.M101846200 Barcenilla, 2000, Phylogenetic relationships of butyrate-producing bacteria from the human gut, Appl Environ Microbiol, 66, 1654, 10.1128/AEM.66.4.1654-1661.2000 Weaver, 1988, Short chain fatty acid distributions of enema samples from a sigmoidoscopy population: an association of high acetate and low butyrate ratios with adenomatous polyps and colon cancer, Gut, 29, 1539, 10.1136/gut.29.11.1539 Simpson, 2000, In vivo measurement of colonic butyrate metabolism in patients with quiescent ulcerative colitis, Gut, 46, 73, 10.1136/gut.46.1.73 Gibson, 1995, Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin, Gastroenterology, 108, 975, 10.1016/0016-5085(95)90192-2 Saulnier, 2009, Microbiology of the human intestinal tract and approaches for its dietary modulation, Curr Pharm Des, 15, 1403, 10.2174/138161209788168128 Vendrame, 2011, Six-week consumption of a wild blueberry powder drink increases bifidobacteria in the human gut, J Agric Food Chem, 59, 12815, 10.1021/jf2028686 López-Sepúlveda, 2008, Wine polyphenols improve endothelial function in large vessels of female spontaneously hypertensive rats, Hypertension, 51, 1088, 10.1161/HYPERTENSIONAHA.107.107672 Shimoda, 2008, Walnut polyphenols prevent liver damage induced by carbon tetrachloride and d-galactosamine: hepatoprotective hydrolyzable tannins in the kernel pellicles of walnut, J Agric Food Chem, 56, 4444, 10.1021/jf8002174 Self, 2002, Regulation of purine hydroxylase and xanthine dehydrogenase from Clostridium purinolyticum in response to purines, selenium, and molybdenum, J Bacteriol, 184, 2039, 10.1128/JB.184.7.2039-2044.2002 Agouni, 2009, Red wine polyphenols prevent metabolic and cardiovascular alterations associated with obesity in Zucker fatty rats (Fa/Fa), PLoS ONE, 4, e5557, 10.1371/journal.pone.0005557 Velagapudi, 2010, The gut microbiota modulates host energy and lipid metabolism in mice, J Lipid Res, 51, 1101, 10.1194/jlr.M002774 Tahri, 1995, Effects of three strains of bifidobacteria on cholesterol, Lett Appl Microbiol, 21, 149, 10.1111/j.1472-765X.1995.tb01028.x Hage, 2007, C-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk, J Am Coll Cardiol, 50, 1115, 10.1016/j.jacc.2007.06.012 Ridker, 2007, Biomarkers for prediction of cardiovascular events, N Engl J Med, 356, 1472, 10.1056/NEJMc070079