Neurolymphomatosis: a rare metastatic complication of diffuse large B-Cell lymphoma

Journal of Neuro-Oncology - Tập 95 - Trang 285-288 - 2009
Marc C. Chamberlain1, James Fink2
1Department of Neurology and Neurological Surgery, Fred Hutchinson Cancer Research Institute, Seattle Cancer Care Alliance, University of Washington, Seattle, USA
2Department of Radiology, University of Washington, Seattle, USA

Tóm tắt

To report the occurrence of neurolymphomatosis in a patient with previously treated systemic diffuse B-cell lymphoma (DLBCL). A case report. University medical center. A 54-year old woman with previously treated DLBCL developed sequential mono-, di- and triparesis 3-months after completion of systemic therapy. MR of lumbar and brachial plexus revealed diffuse involvement of nerve roots and plexus. High-dose methotrexate and involved-field radiotherapy. Neurolymphomatosis, although rare, is increasingly recognized with peripheral and central nervous system MRI. Treatment remains unsatisfactory as treatment with methotrexate-based chemotherapy and irradiation is only partially effective.

Tài liệu tham khảo

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