Mechanisms of angiogenesis and arteriogenesis

Risau, W. Mechanisms of angiogenesis. Nature 386, 671–674 (1997).

Benjamin, L.E., Hemo, I. & Keshet, E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF- B and VEGF. Development 125, 1591–1598 (1998).

Hirschi, K.K. & d'Amore, P.A. Pericytes in the microvasculature. Cardiovasc. Res. 32, 687–698 (1996).

Ferrara, N. Role of vascular endothelial growth factor in the regulation of angiogenesis. Kidney Int 56, 794–814 (1999).

Carmeliet, P. et al. Abnormal blood vessel development and lethality in embryos lacking a single vascular endothelial growth factor allele. Nature 380, 435–439 (1996).

Ferrara, N. et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380, 439–442 (1996).

Shalaby, F., Ho, J., Stanford, W.L. & al, e. A requirement for Flk-1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89, 981–990 (1997).

Fong, G.H., Zhang, L., Bryce, D.M. & Peng, J. Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. Development 126, 3015–3025 (1999).

Dickson, M.C et al. Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice. Development 121, 1845–1854 (1995).

Bader, B.L., Rayburn, H., Crowley, D. & Hynes, R.O. Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins. Cell 95, 507–519 (1998).

Lyden, D. et al. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature 401, 670–677 (1999).

Carmeliet, P. Developmental biology. Controlling the cellular brakes [news]. Nature 401, 657–658 (1999).

Zhong, T.P., Rosenberg, M., Mohideen, M.A., Weinstein, B. & Fishman, M.C. gridlock, an HLH Gene Required for Assembly of the Aorta in Zebrafish. Science 287, 1820–1824 (2000).

Gale, N.W. & Yancopoulos, G.D. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev 13, 1055–1066 (1999).

Takahashi, T. et al. Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med 5, 434–438 (1999).

Peichev, M. et al. Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors. Blood– 95(2000).

Eliceiri, B.P. et al. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol Cell 4, 915–924 (1999).

Thurston, G. et al. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nature Medicine 6, 1–4 (2000).

Maisonpierre, P.C. et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277, 55–60 (1997).

Coussens, L.M. et al. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev 13, 1382–1397 (1999).

Heymans, S. et al. Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure [In Process Citation]. Nat Med 5, 1135–1142 (1999).

Vu, T.H. et al. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 93, 411–422 (1998).

Bajou, K. et al. Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med 4, 923–928 (1998).

Brooks, P.C., Silletti, S., von Schalscha, T.L., Friedlander, M. & Cheresh, D.A. Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell 92, 391–400 (1998).

Taipale, J. et al. Vascular endothelial growth factor receptor-3. Curr Top Microbiol Immunol 237, 85–96 (1999).

Soker, S., Takashima, S., Miao, H.Q., Neufeld, G. & Klagsbrun, M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform- specific receptor for vascular endothelial growth factor. Cell 92, 735–745 (1998).

Gerber, H.P. et al. VEGF is required for growth and survival in neonatal mice. Development 126, 1149–1159 (1999).

Carmeliet, P. et al. Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nat Med 5, 495–502 (1999).

Dumont, D.J. et al. Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science 282, 946–949 (1998).

Ferrara, N. & Alitalo, K. Clinical applications of angiogenic growth factors and their inhibitors. Nat Med 5, 1359–1364 (1999).

Hiratsuka, S., Minowa, O., Kuno, J., Noda, T. & Shibuya, M. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci U S A 95, 9349–9354 (1998).

Suri, C. et al. Increased vascularization in mice overexpressing angiopoietin-1. Science 282, 468–471 (1998).

Zhou, M. et al. Fibroblast growth factor 2 control of vascular tone. Nat Med 4, 201–207 (1998).

Lindahl, P., Hellstrom, M., Kalen, M. & Betsholtz, C. Endothelial-perivascular cell signaling in vascular development: lessons from knockout mice. Curr Opin Lipidol 9, 407–411 (1998).

Gohongi, T. et al. Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor beta1. Nat Med 5, 1203–1208 (1999).

Varner, J.A., Brooks, P.C. & Cheresh, D.A. Review: The integrin αvβ3: angiogenesis and apoptosis. Cell Adhesion Communication 3, 367–374 (1995).

Murohara, T. et al. Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest 101, 2567–2578 (1998).

O'Reilly, M.S. et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppresion of metastases by a Lewis lung carcinoma. Cell 79, 315–328 (1994).

O'Reilly, M.S. et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 88, 277–285 (1997).

Helmlinger, G., Yuan, F., Dellian, M. & Jain, R.K. Interstitial pH and pO2 gradients in solid tumors in vivo : high- resolution measurements reveal a lack of correlation. Nat Med 3, 177–182 (1997).

Carmeliet, P. et al. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell 98, 147–157 (1999).

Jain, R.K. et al. Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor. Proc Natl Acad Sci U S A 95, 10820–10825 (1998).

Alon, T. et al. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med 1, 1024–1028 (1995).

Holash, J., Wiegand, S.J. & Yancopoulos, G.D. New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF. Oncogene 18, 5356–5362 (1999).

Risau, W. Development and differentiation of endothelium. Kidney Int Suppl 67, S3–6 (1998).

Maniotis, A.J. et al. Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. Am J Pathol 155, 739–752 (1999).

Ellerby, H.M. et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med 5, 1032–1038 (1999).

Patan, S. TIE1 and TIE2 receptor tyrosine kinases inversely regulate embryonic angiogenesis by the mechanism of intussusceptive microvascular growth. Microvasc Res 56, 1–21 (1998).

Dettman, R.W., Denetclaw, W. Jr., Ordahl, C.P. & Bristow, J. Common epicardial origin of coronary vascular smooth muscle, perivascular fibroblasts, and intermyocardial fibroblasts in the avian heart. Dev Biol 193, 169–181 (1998).

Creazzo, T.L., Godt, R.E., Leatherbury, L., Conway, S.J. & Kirby, M.L. Role of cardiac neural crest cells in cardiovascular development. Annu Rev Physiol 60, 267–286 (1998).

Suri, C. et al. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87, 1171–1180 (1996).

Li, D.Y. et al. Defective angiogenesis in mice lacking endoglin. Science 284, 1534–1537 (1999).

Yanagisawa, H. et al. Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice. J Clin Invest 102, 22–33 (1998).

Lin, Q. et al. Requirement of the MADS-box transcription factor MEF2C for vascular development. Development 125, 4565–4574 (1998).

Reddi, V., Zaglul, A., Pentz, E.S. & Gomez, R.A. Renin-expressing cells are associated with branching of the developing kidney vasculature. J Am Soc Nephrol 9, 63–71 (1998).

Schaper, W. & Ito, W.D. Molecular mechanisms of coronary collateral vessel growth. Circ Res 79, 911–919 (1996).

Pereira, L. et al. Targetting of the gene encoding fibrillin-1 recapitulates the vascular aspect of Marfan syndrome. Nature Genetics 17, 218–222 (1997).

Li, D.Y. et al. Elastin is an essential determinant of arterial morphogenesis. Nature 393, 276–280 (1998).

Segi, E. et al. Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice. Biochem Biophys Res Commun 246, 7–12 (1998).

Gourdie, R.G., Wei, Y., Kim, D., Klatt, S.C. & Mikawa, T. Endothelin-induced conversion of embryonic heart muscle cells into impulse-conducting Purkinje fibers. Proc Natl Acad Sci U S A 95, 6815–6818 (1998).

Kawasaki, T. et al. A requirement for neuropilin-1 in embryonic vessel formation. Development 126, 4895–4902 (1999).

Semenza, G.L. Hypoxia-inducible factor 1: master regulator of O2 homeostasis. Curr Opin Genet Dev 8, 588–594 (1998).

Maltepe, E., Schmidt, J.V., Baunoch, D., Bradfield, C.A. & Simon, C.M. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 386, 403–407 (1997).

Carmeliet, P. et al. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394, 485–490 (1998).

Li, J. et al. PR39, a peptide regulator of angiogenesis. Nat Med 6, 49–55 (2000).

Vrancken Peeters, M.P. et al. Differences in development of coronary arteries and veins. Cardiovasc Res 36, 101–110 (1997).

Jeltsch, M. et al. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 276, 1423–1425 (1997).

Wigle, J.T. & Oliver, G. Prox1 function is required for the development of the murine lymphatic system. Cell 98, 769–778 (1999).

Sunderkotter, C., Steinbrink, K., Goebeler, M., Bhardwaj, R. & Sorg, C. Macrophages and angiogenesis. J Leukoc Biol 55, 410–422 (1994).

Isner, J. VEGF and neuropathy. Nature Medicine 6, 405–413 (2000): please, complete; I don't have the–full reference yet.

Thurston, G., Murphy, T.J., Baluk, P., Lindsey, J.R. & McDonald, D.M. Angiogenesis in mice with chronic airway inflammation: strain-dependent differences. Am J Pathol 153, 1099–1112 (1998).