Guillain-Barré Syndrome Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Detection and Coronavirus Disease 2019 in a Child

Journal of the Pediatric Infectious Diseases Society - Tập 9 Số 4 - Trang 510-513 - 2020
Maher Ben Khalifa1, Fairouz Zakaria1, Yasser Ragab2, Ahmed Saad3, Ahmed K. Bamaga4, Yasser Emad5, Johannes J. Rasker6
1Pediatric Neurology Department, Dr Erfan and Bagedo General Hospital, Jeddah, Kingdom of Saudi Arabia
2Radiology Department, Faculty of Medicine, Cairo University, Cairo, Egypt
3Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt
4Pediatric Department, Faculty of Medicine, King Abdul-Aziz University, Jeddah, Saudi Arabia
5Rheumatology and Rehabilitation Department, Faculty of Medicine, Cairo University, Cairo, Egypt
6Faculty of Behavioral, Management and Social Sciences, Department of Psychology, Health and Technology, University of Twente, Enschede, The Netherlands

Tóm tắt

Abstract Coronavirus disease (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians in China reported what is believed to be the first adult case of a SARS-CoV-2 infection associated with acute Guillain-Barré syndrome (GBS), followed by 5 adult Italian patients and another case in the United States. In the current report, we present one of the first descriptions of an association of GBS and SARS-CoV-2 infection in a child. In our facility, an 11-year-old boy presented with typical features of GBS and, after 5 days, a morbilliform skin rash over the palms of both hands. Three weeks before the start of the neurological symptoms, the boy had experienced an episode of mild febrile illness with mild respiratory manifestations and a persistent cough. The diagnosis of SARS-CoV-2 infection was confirmed by oropharyngeal swab on reverse-transcription polymerase chain reaction assay. The disease course of our patient strongly suggests a possible relationship between the development of GBS and SARS-CoV-2 infection. The case is discussed in view of previous case reports regarding the association of GBS and COVID-19.

Từ khóa


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Thông tin xuất bản

Journal of the Pediatric Infectious Diseases Society

Tập 9 Số 4

510-513

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