Insights into the Supercritical CO2 Extraction of Perilla Oil and Its Theoretical Solubility

Processes - Tập 9 Số 2 - Trang 239
Ming‐Chi Wei1, Chia-Sui Wang1, Da-Hsiang Wei2, Yu‐Chiao Yang2,3
1Department of Environmental Engineering & Science, Chia Nan University of Pharmacy and Science, Tainan 71710, Taiwan
2Department and Graduate Institute of Pharmacology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
3Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan

Tóm tắt

In the current research, the supercritical carbon dioxide (SCCO2) procedure was used to extract volatile oils from perilla leaves. The yields of the volatile oils and the four main constituents, limonene, perillaldehyde, β-caryophyllene, and (Z,E)-α-farnesene obtained by the SCCO2 procedure were 1.31-, 1.12-, 1.04-, 1.05-, and 1.07-fold higher than those obtained by the hydrodistillation technique, respectively. Furthermore, the duration and temperature of extraction were 40 min and 45 °C lower, respectively, in the former procedure compared to the latter technique. These advantages reveal that SCCO2 not only obtains high-quality extracts, but also meets the requirements of green environmental protection. The theoretical solubilities of the volatile oils acquired by the SCCO2 dynamic extraction at various temperatures and pressures were 1.385 × 10−3–8.971 × 10−3 (g oil/g CO2). Moreover, the three density-based models were well correlated with these theoretical solubility data, with a high coefficient of determination and low average absolute relative deviation.

Từ khóa


Tài liệu tham khảo

Tabanca, 2015, Essential oils of green and red Perilla frutescens as potential sources of compounds for mosquito management, Ind. Crops Prod., 65, 36, 10.1016/j.indcrop.2014.11.043

Torri, 2019, Development of perilla seed oil and extra virgin olive oil blends for nutritional, oxidative stability and consumer acceptance improvements, Food Chem., 286, 584, 10.1016/j.foodchem.2019.02.063

Tian, 2014, Regional variation in components and antioxidant and antifungal activities of Perilla frutescens essential oils in China, Ind. Crops Prod., 59, 69, 10.1016/j.indcrop.2014.04.048

Park, 2015, Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages, Int. J. Mol. Med., 35, 957, 10.3892/ijmm.2015.2101

Yang, Y.C., Wang, C.S., and Wei, M.C. (2020). Development and validation of an ultrasound-assisted supercritical carbondioxide procedure for the production of essential oils from Perilla frutescens. LWT Food Sci. Technol., 128.

Chang, 2014, Extraction and advanced adsorbents for the separation of perillaldehyde from Perilla frutescens (L.) Britton var. crispa f. viridis leaves, Food Sci. Technol. Res., 20, 189, 10.3136/fstr.20.189

You, 2014, Chemical constituents and biological activities of the purple Perilla essential oil against Lasioderma serricorne, Ind. Crops Prod., 61, 331, 10.1016/j.indcrop.2014.07.021

Ahmed, 2019, Identification and quantification of essential oil content and composition, total polyphenols and antioxidant capacity of Perilla frutescens (L.) Britt, Food Chem., 275, 730, 10.1016/j.foodchem.2018.09.155

Chen, F., Liu, S., Zhao, Z., Gao, W., Ma, Y., Wang, X., Yan, S., and Luo, D. (2020). Ultrasound pre-treatment combined with microwave-assisted hydrodistillation of essential oils from Perilla frutescens (L.) Britt. leaves and its chemical composition and biological activity. Ind. Crops Prod., 143.

Yang, Y.C., Wang, C.S., and Wei, M.C. (2021). Insights into the major phenolic acids in Perilla frutescens obtained by a sustainable procedure. J. Ind. Eng. Chem., In Press.

Karlovits, 2015, Optimisation of ultrasound-assisted extraction of natural antioxidants from mustard seed cultivars, J. Sci. Food Agric., 95, 1445, 10.1002/jsfa.6840

Torres, 2015, Isolation of bioactive compounds from sunflower leaves (Helianthus annuus L.) extracted with supercritical carbon dioxide, J. Agric. Food Chem., 63, 6410, 10.1021/acs.jafc.5b02261

Sanjaya, 2014, Investigation on supercritical CO2 extraction of phenolic-phytochemicals from an epiphytic plant tuber (Myrmecodia pendans), J. CO2 Util., 6, 26, 10.1016/j.jcou.2014.03.001

Yousefi, 2019, Supercritical fluid extraction of essential oils, Trends Anal. Chem., 118, 182, 10.1016/j.trac.2019.05.038

Yang, 2014, Simultaneous extraction and quantitation of oleanolic acid and ursolic acid from Scutellaria barbata D. Don by ultrasound-assisted extraction and high-performance liquid chromatography, Chem. Eng. Comm., 201, 482, 10.1080/00986445.2013.777901

Yang, 2014, Ultrasound-assisted extraction and quantitation of oils from Syzygium aromaticum flower bud (clove) with supercritical carbon dioxide, J. Chromatogr. A, 1323, 18, 10.1016/j.chroma.2013.10.098

Yang, 2019, Kinetics and mass transfer considerations for an ultrasound-assisted supercritical CO2 procedure to produce extracts enriched in flavonoids from Scutellaria barbata, J. CO2 Util., 32, 219, 10.1016/j.jcou.2019.04.008

Yang, 2016, A combined procedure of ultrasound-assisted and supercritical carbon dioxide for extraction and quantitation oleanolic and ursolic acids from Hedyotis corymbosa, Ind. Crops Prod., 79, 7, 10.1016/j.indcrop.2015.10.038

Huang, 2011, Comparison of HS-SPME with hydrodistillation and SFE for the analysis of the volatile compounds of Zisu and Baisu, two varietal species of Perilla frutescens of Chinese origin, Food Chem., 125, 268, 10.1016/j.foodchem.2010.08.043

Liu, 2012, Comparison of MAHD with UAE and hydrodistillation for the analysis of volatile oil from four parts of Perilla frutescens cultivated in southern China, Anal. Lett., 45, 1894, 10.1080/00032719.2012.677983

Wei, 2016, Extraction of α-humulene-enriched oil from clove by ultrasound-assisted supercritical carbon dioxide extraction and studies of its fictitious solubility, Food Chem., 210, 172, 10.1016/j.foodchem.2016.04.076

Yang, 2019, Separation and quantification of bioactive flavonoids from Scutellaria barbata using a green procedure, Food Bioprod. Process., 118, 77, 10.1016/j.fbp.2019.09.004

Wei, 2015, Kinetic studies for ultrasound-assisted supercritical carbon dioxide extraction of triterpenic acids from healthy tea ingredient Hedyotis diffusa and Hedyotis corymbosa, Sep. Purif. Technol., 142, 316, 10.1016/j.seppur.2015.01.008

Yang, Y.C., Wang, C.S., and Wei, M.C. (2020). A green approach for the extraction and characterization of oridonin and ursolic and oleanolic acids from Rabdosia rubescens and its kinetics behavior. Food Chem., 319.

Ferreira, 2002, Modeling the supercritical fluid extraction of black pepper (Piper nigrum L.) essential oil, J. Food Eng., 54, 263, 10.1016/S0260-8774(01)00212-6

Santana, 2019, Pressurized liquid- and supercritical fluid extraction of crude and waste seeds of guarana (Paullinia cupana): Obtaining of bioactive compounds and mathematical modeling, Food Bioprod. Process., 117, 194, 10.1016/j.fbp.2019.07.007

Wei, 2017, Isolation of triterpenic acid-rich extracts from Hedyotis corymbosa using ultrasound-assisted supercritical carbon dioxide extraction and determination of their fictitious solubilities, J. Ind. Eng. Chem., 48, 202, 10.1016/j.jiec.2017.01.003

Yang, 2018, Development and characterization of a green procedure for apigenin extraction from Scutellaria barbata D. Don, Food Chem., 252, 381, 10.1016/j.foodchem.2017.12.086

Said, 2014, A green separation of Lagenaria siceraria seed oil, Ind. Crops Prod., 52, 796, 10.1016/j.indcrop.2013.12.009

Wei, M.C., Yang, Y.C., and Hong, S.J. (2015). Determination of oleanolic and ursolic acids in Hedyotis diffusa using hyphenated ultrasound-assisted supercritical carbon dioxide extraction and chromatography. Evid. Based Complement. Alternat. Med., 2015.

Tomita, 2014, Extraction of rice bran oil by supercritical carbon dioxide and solubility consideration, Sep. Purif. Technol., 12, 5319

Rudyk, 2018, Effect of temperature on crude oil extraction by SC-CO2 at 40–70 °C and 40–60 MPa, J. CO2 Util., 24, 471, 10.1016/j.jcou.2018.02.009

Couto, 2018, Coenzyme Q10 solubility in supercritical CO2 using a dynamic system, J. CO2 Util., 24, 315, 10.1016/j.jcou.2018.01.012

Yang, 2015, Ethanol solution-modified supercritical carbon dioxide extraction of triterpenic acids from Hedyotis corymbosa with ultrasound assistance and determination of their solubilities, Sep. Purif. Technol., 150, 204, 10.1016/j.seppur.2015.06.037

Wei, 2016, Development of a green alternative procedure for simultaneous separation and quantification of clove oil and its major bioactive constituents, ACS Sustain. Chem. Eng., 4, 6491, 10.1021/acssuschemeng.6b01263

Chrastil, 1982, Solubility of solids and liquids in supercritical gases, J. Phys. Chem., 86, 3016, 10.1021/j100212a041

Bartle, 1991, Solubilities of solids and liquids of low volatility in supercritical carbon dioxide, J. Phys. Chem. Ref. Data, 20, 713, 10.1063/1.555893

Kumar, 1988, Modeling the solubility of solids in supercritical fluids with density as the independent variable, J. Supercrit. Fluids, 1, 15, 10.1016/0896-8446(88)90005-8

Yang, 2017, Production of oridonin-rich extracts from Rabdosia rubescens using hyphenated ultrasound-assisted supercritical carbon dioxide extraction, J. Sci. Food Agric., 97, 3323, 10.1002/jsfa.8182