Systems Biology: A Brief Overview

American Association for the Advancement of Science (AAAS) - Tập 295 Số 5560 - Trang 1662-1664 - 2002
Hiroaki Kitano1
1Sony Computer Science Laboratories, Inc., 3-14-13 Higashi-Gotanda, Shinagawa, Tokyo 141-0022, Japan, and Kitano Symbiotic Systems Project, ERATO, JST, and the Systems Biology Institute, Suite 6A, M31, 6-31-15 Jingumae, Shibuya, Tokyo 150-0001, Japan.

Tóm tắt

To understand biology at the system level, we must examine the structure and dynamics of cellular and organismal function, rather than the characteristics of isolated parts of a cell or organism. Properties of systems, such as robustness, emerge as central issues, and understanding these properties may have an impact on the future of medicine. However, many breakthroughs in experimental devices, advanced software, and analytical methods are required before the achievements of systems biology can live up to their much-touted potential.

Từ khóa


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I thank J. Doyle M. Simon and members of ERATO Kitano project for fruitful discussions. Supported by the ERATO and BIRD program of the Japan Science and Technology Corporation and the Rice Genome and Simulation Project of the Ministry of Agriculture Japan.