Paraneoplastic opsoclonus-myoclonus-ataxia syndrome revealing dual malignancy
Tóm tắt
Dual malignancy has been rarely associated to paraneoplastic syndromes. We describe an unusual case of metachronous small cell lung carcinoma revealed by opsoclonus-myoclonus ataxia syndrome in a 69-year-old patient with known prostate adenocarcinoma, with positive anti-Hu and anti-Yo antibodies and good responsiveness to corticosteroids and chemotherapy.
Tài liệu tham khảo
Ghosh S, Rao PB, Sarkar S, Kotne S, Turlapati SP, Mishra A (2014) A rare case of a synchronous anaplastic carcinoma thyroid with ductal carcinoma breast. Case Rep Oncol Med 2014:468159. doi:10.1155/2014/468159
Stieler W, Plewig G (1987) Acanthosis nigricans maligna and Leser-Trélat sign in double malignancy of the breast and stomach. Z Hautkr 62:344–366
Ng SS, Teo RY, Seah PP (2012) A case of bullous pemphigoid in a patient with dual cancers, fortuitous or paraneoplastic? Ann Acad Med Singapore 41:313–314
Lin LY, Chang MH, Lee WJ (2014) Paraneoplastic limbic encephalitis associated with adenocarcinoma of lung. Acta Neurol Taiwan 23:108–112
Thapa P, Basu S (2015) Diagnosis of dual malignancy by 18F-FDG-PET/CT in the setting of paraneoplastic cerebellar degeneration. J Nucl Med Technol 44:52–53
Berger B, Bischler P, Dersch R, Hottenrott T, Rauer S, Stich O (2015) “Non-classical” paraneoplastic neurological syndromes associated with well-characterized antineuronal antibodies as compared to “classical” syndromes–more frequent than expected. J Neurol Sci 352:58–61. doi:10.1016/j.jns.2015.03.027
Baloh RW, DeRossett SE, Cloughesy TF, Kuncl RW, Miller NR, Merrill J, Posner JB (1993) Novel brainstem syndrome associated with prostate carcinoma. Neurology 43:2591–2596
Laroumagne S, Elharrar X, Coiffard B, Plojoux J, Dutau H, Breen D, Astoul P (2014) “Dancing eye syndrome” secondary to opsoclonus-myoclonus syndrome in small-cell lung cancer. Case Rep Med. doi:10.1155/2014/545490