Ana Vallari1, Vera Holzmayer1, Barbara J. Harris1, Julie Yamaguchi1, Charlotte Ngansop2, Florence Makamche2, Dora Mbanya2, Lazare Kaptué2,3, Nicaise Ndembi4,2, Lutz Gürtler5, Sushil G. Devare1, Catherine A. Brennan1
1Abbott Diagnostics, Abbott Park, Illinois
2Université de Yaoundé I, Yaoundé, Cameroon
3Université Des Montagnes, Bangangté, Cameroon
4Institute of Human Virology, Abuja, Nigeria
5Max von Pettenkofer Institute, Ludwig Maximilian University, Munich, Germany
Tóm tắt
ABSTRACT
We report the second human immunodeficiency virus (HIV) belonging to the new HIV type 1 (HIV-1) group P lineage that is closely related to the simian immunodeficiency virus found in gorillas. This virus was identified in an HIV-seropositive male hospital patient in Cameroon, confirming that the group P virus is circulating in humans. Results from screening 1,736 HIV-seropositive specimens collected in Cameroon indicate that HIV-1 group P infections are rare, accounting for only 0.06% of HIV infections. Despite its rarity, group P shows evidence of adaptation to humans.