The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor
Tài liệu tham khảo
Barker, 1987, Potentiation of γ-aminobutyric acid-activated chloride conductance by a steroid anaesthetic in cultured rat spinal neurones, J. Physiol., 386, 485, 10.1113/jphysiol.1987.sp016547
Baulieu, 1987, Neurosteroids: pregnenolone and dehydroepiandrosterone in the rat brain, 89
Demirgoren, 1989, Binding of pregnenolone sulfate to rat brain membranes: interaction with the GABAA receptor complex, Soc. Neurosci. Abstr., 15, 397.4
Enna, 1986, GABA receptors: an overview, 241
Hamill, 1981, Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches, Pflu¨gers Arch., 391, 85, 10.1007/BF00656997
Harrison, 1984, Modulation of GABAA receptor complex by steroid anaesthetic, Brain Research, 323, 287, 10.1016/0006-8993(84)90299-3
Harrison, 1987, Structure—activity relationships for steroid interaction with the γ-aminobutyric acidA receptor complex, J. Pharm. Exp. Ther., 241, 346
Hu, 1987, Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone, 84, 8215
Iwamori, 1976, Steroid sulfatase in brain: comparison of sulfohydrolase activities for various steroid sulfates in normal and pathological brains, including the various forms of metachromatic leukodystrophy, J. Neurochem., 27, 1389, 10.1111/j.1471-4159.1976.tb02620.x
Le Goascogne, 1987, Neurosteroids: cytochrome P-450 in rat brain, Science, 237, 1212, 10.1126/science.3306919
Majewska, 1987, Actions of steroids on neuron: role in personality, mood, stress, and disease, Integr. Psychiatry, 5, 258
Majewska, 1985, Glucocorticoids are modulators of GABAA receptors in brain, Brain Research, 339, 178, 10.1016/0006-8993(85)90641-9
Majewska, 1986, Steroid hormone metabolites are barbiturate like modulators of the GABA receptor, Science, 232, 1004, 10.1126/science.2422758
Majewska, 1987, Pregnenolone-sulfate: an endogenous antendogenous antagonist of the γ-aminobutyric acid receptor complex in brain?, Brain Research, 404, 355, 10.1016/0006-8993(87)91394-1
Majewska, 1988, Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons, Neurosci. Lett., 90, 279, 10.1016/0304-3940(88)90202-9
Majewska, 1989, Pregnenolone sulfate antagonizes barbiturate-induced hypnosis, Pharmacol. Biochem. Behav., 33, 701, 10.1016/0091-3057(89)90410-3
Mienville, 1989, Pregnenolone sulfate antagonizes GABAA receptor mediated currents via a reduction of channel opening frequency, Brain Research, 489, 190, 10.1016/0006-8993(89)90024-3
Munson, 1980, Ligand: a versatile computerized approach for characterization of ligand-binding systems, Anal. Biochem., 107, 220, 10.1016/0003-2697(80)90515-1
Murase, 1989, Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons, Neurosci. Lett., 103, 56, 10.1016/0304-3940(89)90485-0
Robel, 1984, Pregnenolone, dehydroepiandrosterone, and their sulfate esters in rat brain, 185
Silva, 1988, 5,7-Dihydroxytryptamine identifies living dopaminergic neurons in mesencephalic cultures, 85, 7346
