Lipoxins as biomarkers of lupus and other inflammatory conditions

Das UN: Clinical laboratory tools to diagnose inflammation. Advances in Clinical Chemistry. 2006, 41: 189-229. Serhan CN: Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution. Prostaglandins Leukot Essent Fatty Acids. 2005, 73: 141-162. 10.1016/j.plefa.2005.05.002 Claria J, Serhan CN: Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc Natl Acad Sci USA. 1995, 92: 9475-9479. 10.1073/pnas.92.21.9475 Das UN: Essential fatty acids: Biochemistry, physiology, and pathology. Biotechnology J. 2006, 1: 420-439. 10.1002/biot.200600012. Serhan CN, Hong S, Gronert K, Colgan SP, Devchand PR, Mirick G, Moussignac R-L: Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammatory signals. J Exp Med. 2002, 196: 1025-1037. 10.1084/jem.20020760 Das UN: Essential fatty acids- a review. Current Pharmaceutical Biotechnol. 2006, 7: 467-482. 10.2174/138920106779116856. Chiang N, Arita M, Serhan CN: Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. Prostaglandins Leukot Essen Fatty Acids. 2005, 73: 163-177. 10.1016/j.plefa.2005.05.003. Levy BD, Clish CB, Schmidt B, Gronert K, Serhan CN: Lipid mediator class switching during acute inflammation signals in resolution. Nat Immunol. 2001, 2: 612-619. 10.1038/89759 Serhan CN, Maddox JF, Petasis NA, Akritopoulou-Zanze I, Papayianni A, Brady HR, Colgan SP, Madara JL: Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils. Biochemistry. 1995, 34: 14609-14615. 10.1021/bi00044a041 Zordoky BN, El-Kadi AO: Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases. Pharmacol Ther. 2010, 125: 446-463. 10.1016/j.pharmthera.2009.12.002 Nithipatikom K, Gross GJ: Review article: epoxyeicosatrienoic acids: novel mediators of cardioprotection. J Cardiovasc Pharmacol Ther. 2010, 15: 112-119. 10.1177/1074248409358408 Campbell WB, Fleming I: Epoxyeicosatrienoic acids and endothelium-dependent responses. Pflugers Arch. 2010, 459: 881-895. 10.1007/s00424-010-0804-6 Arnold C, Konkel A, Fischer R, Schunck WH: Cytochrome P450-dependent metabolism of omega-6 and omega-3 long-chain polyunsaturated fatty acids. Pharmacol Rep. 2010, 62: 536-547. Kroetz DL, Zeldin DC: Cytochrome P450 pathways of arachidonic acid metabolism. Curr Opin Lipidol. 2002, 13: 273-283. 10.1097/00041433-200206000-00007 Gao L, Yin H, Milne GL, Porter NA, Morrow JD: Formation of F-ring isoprostane-like compounds (F3-isoprostanes) in vivo from eicosapentaenoic acid. J Biol Chem. 2006, 281: 14092-14099. 10.1074/jbc.M601035200 Serhan CN, Clish CB, Brannon J, Colgan SP, Chiang N, Gronert K: Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing. J Exp Med. 2000, 192: 1197-1204. 10.1084/jem.192.8.1197 Serhan CN, Clish CB, Brannon J, Colgan SP, Gronert K, Chiang N: Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions. J Physiol Pharmacol. 2000, 51 (4 Pt 1): 643-654. Marcheselli VL, Hong S, Lukiw WJ, Tian XH, Gronet K, Musto A, Hardy M, Gimenez JM, Chiang N, Serhan CN, Bazan NG: Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. J Biol Chem. 2003, 278: 43807-43817. 10.1074/jbc.M305841200 Hong S, Gronert K, Devchand PR, Moussignac RL, Serhan CN: Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J Biol Chem. 2003, 278: 14677-14687. 10.1074/jbc.M300218200 Romano M, Luciotti G, Gangemi S, Marinucci F, Prontera C, D'Urbano E, Davì G: Urinary excretion of lipoxin A(4) and related compounds: development of new extraction techniques for lipoxins. Lab Invest. 2002, 82: 1253-1254. Gangemi S, Luciotti G, D'Urbano E, Mallamace A, Santoro D, Bellinghieri G, Davi G, Romano M: Physical exercise increases urinary excretion of lipoxin A4 and related compounds. J Appl Physiol. 2003, 94: 2237-2240. Gangemi S, Pescara L, D'Urbano E, Basile G, Nicita-Mauro V, Davì G, Romano M: Aging is characterized by a profound reduction in anti-inflammatory lipoxin A4 levels. Exp Gerontol. 2005, 40: 612-614. 10.1016/j.exger.2005.04.004 Wu SH, Liao PY, Yin PL, Zhang YM, Dong L: Inverse temporal changes of lipoxin A4 and leukotrienes in children with Henoch-Schönlein purpura. Prostaglandins Leukot Essent Fatty Acids. 2009, 80: 177-183. 10.1016/j.plefa.2009.01.008 Katoh T, Lakkis FG, Makita N, Badr KF: Co-regulated expression of glomerular 12/15-lipoxygenase and interleukin-4 mRNAs in rat nephrotoxic nephritis. Kidney Int. 1994, 46: 341-349. 10.1038/ki.1994.280 Nassar GM, Badr KF: Role of leukotrienes and lipoxygenases in glomerular injury. Miner Electrolyte Metab. 1995, 21: 262-270. Papayianni A, Serhan CN, Phillips ML, Rennke HG, Brady HR: Transcellular biosynthesis of lipoxin A4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis. Kidney Int. 1995, 47: 1295-1302. 10.1038/ki.1995.184 O'Meara YM, Brady HR: Lipoxins, leukocyte recruitment and the resolution phase of acute glomerulonephritis. Kidney Int Suppl. 1997, 58: S56-S61. Wu SH, Liao PY, Yin PL, Zhang YM, Dong L: Elevated expressions of 15-lipoxygenase and lipoxin A4 in children with acute poststreptococcal glomerulonephritis. Am J Pathol. 2009, 174: 115-122. 10.2353/ajpath.2009.080671 Lattin JE, Schroder K, Su AI, Walker JR, Zhang J, Wiltshire T, Saijo K, Glass CK, Hume DA, Kellie S, Sweet MJ: Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome Res. 2008, 4: 5- 10.1186/1745-7580-4-5 Milligan G, Stoddart LA, Brown AJ: G protein-coupled receptors for free fatty acids. Cell Signal. 2006, 18: 1360-1365. 10.1016/j.cellsig.2006.03.011 Oh DY, Talukdar S, Bae EJ, Imamura T, Morinaga H, Fan W, Li P, Lu WJ, Watkins SM, Olefsky JM: GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell. 2010, 142: 687-698. 10.1016/j.cell.2010.07.041 Suresh Y, Das UN: Protective action of arachidonic acid against alloxan-induced cytotoxicity and diabetes mellitus. Prostaglandins Leukotrienes Essential Fatty Acids. 2001, 64: 37-52. 10.1054/plef.2000.0236. Suresh Y, Das UN: Long-chain polyunsaturated fatty acids and chemically-induced diabetes mellitus: Effect of ω-6 fatty acids. Nutrition. 2003, 19: 93-114. 10.1016/S0899-9007(02)00856-0 Suresh Y, Das UN: Long-chain polyunsaturated fatty acids and chemically-induced diabetes mellitus: Effect of ω-3 fatty acids. Nutrition. 2003, 19: 213-228. 10.1016/S0899-9007(02)00855-9 Stene LC, Joner G, : Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large, population-based, case-control study. Am J Clin Nutr. 2003, 78: 1128-1134. Stene LC, Ulriksen J, Magnus P, Joner G: Use of cod liver oil during pregnancy associated with lower risk of Type I diabetes in the offspring. Diabetologia. 2000, 43: 1093-1098. 10.1007/s001250051499 Bellenger J, Bellenger S, Bataille A, Massey KA, Nicolaou A, Rialland M, Tessier C, Kang JX, Narce M: High Pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: inflammatory pathway inhibition. Diabetes. White PJ, Arita M, Taguchi R, Kang JX, Marette A: Transgenic restoration of long-chain n-3 fatty acids in insulin target tissues improves resolution capacity and alleviates obesity-linked inflammation and insulin resistance in high-fat-fed mice. Diabetes. 2010, 59: 3066-3073. 10.2337/db10-0054 Das UN, Puskás LG: Transgenic fat-1 mouse as a model to study the pathophysiology of cardiovascular, neurological and psychiatric disorders. Lipids Health Dis. 2009, 8: 61- 10.1186/1476-511X-8-61 Bonventre JV: Phospholipase A2 and signal transduction. J Am Soc Nephrol. 1992, 3: 128-150. Levy BD, Clish CB, Schmidt B, Gronert K, Serhan CN: Lipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol. 2001, 2: 612-619. 10.1038/89759 Godson C, Mitchell S, Harvey K, Petasis NA, Hogg N, Brady HR: Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages. J Immunol. 2000, 164: 1663-1667. Gilroy DW, Colville-Nash PR, Willis D, Chivers J, Paul-Clark MJ, Willoughby DA: Inducible cyclooxygenase may have anti-inflammatory properties. Nat Med. 1999, 5: 698-701. 10.1038/9550 Gilroy DW, Newson J, Sawmynaden P, Willoughby DA, Croxtall JD: A novel role for phospholipase A2 isoforms in the checkpoint control of acute inflammation. FASEB J. 2004, 18: 489-498. 10.1096/fj.03-0837com Cominelli F, Nast CC, Llerena R, Dinarello CA, Zipser RD: Interleukin 1 suppresses inflammation in rabbit colitis. Mediation by endogenous prostaglandins. J Clin Invest. 1990, 85: 582-586. 10.1172/JCI114476 Schwab JH, Anderle SK, Brown RR, Dalldorf FG, Thompson RC: Pro- and anti- inflammatory roles of interleukin-1 in recurrence of bacterial cell wall-induced arthritis in rats. Infect Immun. 1991, 59: 4436-4442. Serhan CN, Hong S, Gronert K, Colgan SP, Devchand PR, Mirick G, Moussignac R-L: Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med. 2002, 196: 1025-1037. 10.1084/jem.20020760 Croxtall JD, Choudhury Q, Tokumoto H, Flower RJ: Lipocortin-1 and the control of arachidonic acid release in cell signalling. Glucocorticoids inhibit G protein-dependent activation of cPLA2 activity. Biochem Pharmacol. 1995, 50: 465-474. 10.1016/0006-2952(95)00156-T