Biomarkers of dietary intake of flavonoids and phenolic acids for studying diet–cancer relationship in humans

Springer Science and Business Media LLC - Tập 47 Số S2 - Trang 60-68 - 2008
Jakob Linseisen1, Sabine Rohrmann1
1Unit of Nutritional Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany

Tóm tắt

Từ khóa


Tài liệu tham khảo

Adlercreutz H, Kiuru P, Rasku S, Wähälä K, Fotsis T (2004) An isotope dilution gas chromatographic–mass spectrometric method for the simultaneous assay of estrogens and phytoestrogens in urine. J Steroid Biochem Mol Biol 92:399–411

Bolarinwa A, Linseisen J (2005) Validated application of a new high- performance liquid chromatographic method for the determination of selected flavonoids and phenolic acids in human plasma using electrochemical detection. J Chromatogr B Analyt Technol Biomed Life Sci 823:143–151

Dai Q, Franke AA, Jin F, Shu XO, Hebert JR, Custer LJ et al (2002) Urinary excretion of phytoestrogens and risk of breast cancer among Chinese women in Shanghai. Cancer Epidemiol Biomarkers Prev 11:815–821

de Vries JH, Hollman PC, Meyboom S, Buysman MN, Zock PL, van Staveren WA, Katan MB (1998) Plasma concentrations and urinary excretion of the antioxidant flavonols quercetin and kaempferol as biomarkers for dietary intake. Am J Clin Nutr 68:60–65

den Tonkelaar I, Keinan-Boker L, Veer PV, Arts CJ, Adlercreutz H, Thijssen JH et al (2001) Urinary phytoestrogens and postmenopausal breast cancer risk. Cancer Epidemiol Biomarkers Prev 10:223–228

Erlund I, Silaste ML, Alfthan G, Rantala M, Kesaniemi YA, Aro A (2002) Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables. Eur J Clin Nutr 56:891–898

Fuchs D, Piller R, Linseisen J, Daniel H, Wenzel U (2007) The human peripheral blood mononuclear cell proteome responds to a dietary flaxseed-intervention and proteins identified suggest a protective effect in atherosclerosis. Proteomics 7:3278–3288

Grace PB, Mistry NS, Carter MH, Leathem AJ, Teale P (2007) High throughput quantification of phytoestrogens in human urine and serum using liquid chromatography/tandem mass spectrometry (LC–MS/MS). J Chromatogr B Analyt Technol Biomed Life Sci 853:138–146

Grace PB, Taylor JI, Low YL, Luben RN, Mulligan AA, Botting NP et al (2004) Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-Norfolk. Cancer Epidemiol Biomarkers Prev 13:698–708

Hertog MG, Hollman PC, Katan MB, Kromhout D (1993) Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands. Nutr Cancer 20:21–29

Hollman PC, Hertog MG, Katan MB (1996) Role of dietary flavonoids in protection against cancer and coronary heart disease. Biochem Soc Trans 24:785–789

Howells LM, Moiseeva EP, Neal CP, Foreman BE, Andreadi CK, Sun YY, Hudson EA, Manson MM (2007) Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals. Acta Pharmacol Sin 28:1274–1304

Hulten K, Winkvist A, Lenner P, Johansson R, Adlercreutz H, Hallmans G (2002) An incident case-referent study on plasma enterolactone and breast cancer risk. Eur J Nutr 41:168–176

Ingram D, Sanders K, Kolybaba M, Lopez D (1997) Case–control study of phyto-oestrogens and breast cancer. Lancet 350:990–994

Ito H, Gonthiera MP, Manach C, Morand C, Mennen L, Remesy C et al (2004) High-throughput profiling of dietary polyphenols and their metabolites by HPLC–ESI–MS–MS in human urine. Biofactors 22:241–243

Kaaks R, Riboli E, Sinha R (1997) Biochemical markers of dietary intake. In: Toniolo P et al. (ed) Application of biomarkers in cancer epidemiology. IARC Scientific Publications No. 142, IARC, Lyon

Kilkkinen A, Pietinen P, Klaukka T, Virtamo J, Korhonen P, Adlercreutz H (2002) Use of oral antimicrobials decreases serum enterolactone concentration. Am J Epidemiol 155:472–477

Kilkkinen A, Virtamo J, Vartiainen E, Sankila R, Virtanen MJ, Adlercreutz H, Pietinen P (2004) Serum enterolactone concentration is not associated with breast cancer risk in a nested case–control study. Int J Cancer 108:277–280

Kipnis V, Subar AF, Midthune D, Freedman LS, Ballard-Barbash R, Troiano RP, Bingham S, Schoeller DA, Schatzkin A, Carroll RJ (2003) Structure of dietary measurement error: results of the OPEN biomarker study. Am J Epidemiol 158:14–21; discussion 22–26

Manach C, Donovan JL (2004) Pharmacokinetics and metabolism of dietary flavonoids in humans. Free Radic Res 38:771–785

Manach C, Scalbert A, Morand C, Remesy C, Jimenez L (2004) Polyphenols: food sources and bioavailability. Am J Clin Nutr 79:727–747

Manach C, Williamson G, Morand C, Scalbert A, Remesy C (2005) Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 81(suppl 1):230S–242S

Manson MM, Foreman BE, Howells LM, Moiseeva EP (2007) Determining the efficacy of dietary phytochemicals in cancer prevention. Biochem Soc Trans 35:1358–63

Merken HM, Beecher GR (2000) Measurement of food flavonoids by high-performance liquid chromatography: a review. J Agric Food Chem 48:577–599

Murkies A, Dalais FS, Briganti EM, Burger HG, Healy DL, Wahlqvist ML et al (2000) Phytoestrogens and breast cancer in postmenopausal women: a case control study. Menopause 7:289–296

Nielsen SE, Freese R, Kleemola P, Mutanen M (2002) Flavonoids in human urine as biomarkers for intake of fruits and vegetables. Cancer Epidemiol Biomarkers Prev 11:459–466

Noroozi M, Burns J, Crozier A, Kelly IE, Lean ME (2000) Prediction of dietary flavonol consumption from fasting plasma concentration or urinary excretion. Eur J Clin Nutr 54:143–149

Pietinen P, Stumpf K, Mannisto S, Kataja V, Uusitupa M, Adlercreutz H (2001) Serum enterolactone and risk of breast cancer: a case–control study in eastern Finland. Cancer Epidemiol Biomarkers Prev 10:339–344

Piller R, Chang-Claude J, Linseisen J (2006) Plasma enterolactone and genistein and the risk of premenopausal breast cancer. Eur J Cancer Prev 15:225–232

Radtke J, Linseisen J, Wolfram G (2002) Fasting plasma concentrations of selected flavonoids as markers of their ordinary dietary intake. Eur J Nutr 41:203–209

Ritchie MR, Morton MS, Deighton N, Blake A, Cummings JH (2004) Plasma and urinary phyto-oestrogens as biomarkers of intake: validation by duplicate diet analysis. Br J Nutr 91:447–457

Robbins RJ (2003) Phenolic acids in foods: an overview of analytical methodology. J Agric Food Chem 51:2866–2887

Rundle AG, Vineis P, Ahsan H (2005) Design options for molecular epidemiology research within cohort studies. Cancer Epidemiol Biomarkers Prev 14:1899–1907

Sun CL, Yuan JM, Lee MJ, Yang CS, Gao YT, Ross RK, et al. (2002) Urinary tea polyphenols in relation to gastric and esophageal cancers: a prospective study of men in Shanghai, China. Carcinogenesis 23:1497–1503

Thomasset SC, Berry DP, Garcea G, Marczylo T, Steward WP, Gescher AJ (2007) Dietary polyphenolic phytochemicals—promising cancer chemopreventive agents in humans? A review of their clinical properties. Int J Cancer 120:451–458

Verheus M, van Gils CH, Keinan-Boker L, Grace PB, Bingham SA, Peeters PH (2007) Plasma phytoestrogens and subsequent breast cancer risk. J Clin Oncol 25:648–655

Verkasalo PK, Appleby PN, Allen NE, Davey G, Adlercreutz H, Key TJ (2001) Soya intake and plasma concentrations of daidzein and genistein: validity of dietary assessment among eighty British women (Oxford arm of the European Prospective Investigation into Cancer and Nutrition). Br J Nutr 86:415–421

Vineis P, Gallo V (2007) The epidemiological theory: principles of biomarker validation. In: Vineis P, Gallo V (eds) Epidemiological concepts of validation of biomarkers for the identification/quantification of environmental carcinogenic exposures. ECNIS publications 3, NOFER Institute, Lodz, pp 9–18

Vineis P, Perera F (2007) Molecular epidemiology and biomarkers in etiologic cancer research: the new in light of the old. Cancer Epidemiol Biomarkers Prev 16:1954–1965

Wang GJ, Lapcik O, Hampl R, Uehara M, Al-Maharik N, Stumpf K et al (2000) Time-resolved fluoroimmunoassay of plasma daidzein and genistein. Steroids 65:339–348

Williamson G, Manach C (2005) Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. Am J Clin Nutr 81(suppl 1):243S–255S

Yang CS, Landau JM, Huang MT, Newmark HL (2001) Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu Rev Nutr 21:381–406

Yuan JM, Gao YT, Yang CS, Yu MC (2007) Urinary biomarkers of tea polyphenols and risk of colorectal cancer in the Shanghai Cohort Study. Int J Cancer 120:1344–1350

Zeleniuch-Jacquotte A, Adlercreutz H, Shore RE, Koenig KL, Kato I, Arslan AA, Toniolo P (2004) Circulating enterolactone and risk of breast cancer: a prospective study in New York. Br J Cancer 91:99–105

Zheng W, Dai Q, Custer LJ, Shu XO, Wen WQ, Jin F et al (1999) Urinary excretion of isoflavonoids and the risk of breast cancer. Cancer Epidemiol Biomarkers Prev 8:35–40