Engineering the Soil Bacterium Pseudomonas putida for Arsenic Methylation

Applied and Environmental Microbiology - Tập 79 Số 14 - Trang 4493-4495 - 2013
Jian Chen1,2, Jie Qin1, Yong‐Guan Zhu3,2, Vı́ctor de Lorenzo4, Barry P. Rosen1
1Department of Cellular Biology and Pharmacology, Florida International University, Herbert Wertheim College of Medicine, Miami, Florida, USA
2State Key Lab of Regional and Urban Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China
3Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, People’s Republic of China
4Centro Nacional de Biotecnolog�a-CSIC, Campus UAM-Cantoblanco, Madrid, Spain

Tóm tắt

Accumulation of arsenic has potential health risks through consumption of food. Here, we inserted the arsenite [As(III)] S -adenosylmethionine methyltransferase (ArsM) gene into the chromosome of Pseudomonas putida KT2440. Recombinant bacteria methylate inorganic arsenic into less toxic organoarsenicals. This has the potential for bioremediation of environmental arsenic and reducing arsenic contamination in food.

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Thông tin xuất bản

Applied and Environmental Microbiology

Tập 79 Số 14

4493-4495

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