Plasmid-mediated ROB-1 beta-lactamase in Pasteurella multocida from a human specimen

Antimicrobial Agents and Chemotherapy - Tập 35 Số 11 - Trang 2419-2422 - 1991
A Rosenau1, A. Labigne1, F. Escande1, P Courcoux1, A. Philippon1
1Laboratoire de Microbiologie, Groupe Hospitalier Boucicaut-Vaugirard, Paris, France.

Tóm tắt

A Pasteurella multocida human isolate was resistant to beta-lactams because of production of ROB-1 beta-lactamase. The beta-lactamase was encoded by a 4.3-kb plasmid closely related to that of a Pasteurella bovine strain, as shown by Sau3A restriction profile and hybridization with a plasmid probe containing the blaROB-1 gene.

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