Edible flowers as sources of bioactive compounds: Determination of phenolic extraction conditions

Al-Snafi, 2018, Pharmacology and medicinal properties of Jasminum officinale: a review, Indo Am. J. Pharm. Sci., 2191 Alara, 2021, Extraction of phenolic compounds: a review, Curr. Res. Nutr. Food Sci., 4, 200 Almasian, 2020, Polyurethane/carboxymethylcellulose nanofibers containing Malva sylvestris extract for healing diabetic wounds: preparation, characterization, in vitro and in vivo studies, Mater. Sci. Eng. C, 114, 10.1016/j.msec.2020.111039 Anh, 2019, Effect of extraction process on extraction yeild, total polyphenol content and antioxidant activity of Jasminum Subtriplinerve, Key Eng. Mater., 814, 527, 10.4028/www.scientific.net/KEM.814.527 Apak, 2004, Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method, J. Agric. Food Chem., 52, 7970, 10.1021/jf048741x Aydar, 2018, Utilization of response surface methodology in optimization of extraction of plant materials Azwanida, 2015, A review on the extraction methods use in medicinal plants, principle, strength and limitation, Med. Aromatic Plants, 4 Baczek, 2017, (L.) hill raw materials, Int. J. Anasl. Chem., 10.1155/2017/2871579 Bakshi, 2022, Bioactive constituents of saffron plant: extraction, encapsulation and their food and pharmaceutical applications, Appl. Food Res., 2, 10.1016/j.afres.2022.100076 Barros, 2010, Leaves, flowers, immature fruits and leafy flowered stems of Malva sylvestris: a comparative study of the nutraceutical potential and composition, Food Chem. Toxicol., 48, 1466, 10.1016/j.fct.2010.03.012 Beghdad, 2014, Antioxidant activity, phenolic and flavonoid content in leaves, flowers, stems and seeds of mallow (Malva sylvestris L.) from North Western of Algeria, Afr. J. Biotechnol., 13 Benzie, 1996, The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay, Anal. Biochem., 239, 70, 10.1006/abio.1996.0292 Boots, 2008, Health effects of quercetin: from antioxidant to nutraceutical, Eur. J. Pharmacol., 585, 325, 10.1016/j.ejphar.2008.03.008 Chen, 2013, A review of the dietary flavonoid, kaempferol on human health and cancer chemoprevention, Food Chem., 138, 2099, 10.1016/j.foodchem.2012.11.139 Chilku, 2017, Antioxidant and antibacterial properties of some commercial plants from Macedonia, World J. Pharm. Pharmaceut. Sci., 6, 1767 Choi, 2015, Extraction conditions for phenolic compounds with antioxidant activities from white rose petals, J. Appl. Biol. Chem., 58, 117, 10.3839/jabc.2015.021 Dai, 2010, Plant phenolics: extraction, analysis and their antioxidant and anticancer properties, Molecules, 15, 7313, 10.3390/molecules15107313 de Morais, 2020, Antioxidant activity and bioaccessibility of phenolic compounds in white, red, blue, purple, yellow and orange edible flowers through a simulated intestinal barrier, Food Res. Int., 131, 10.1016/j.foodres.2020.109046 DellaGreca, 2009, Antioxidant and radical scavenging properties of Malva sylvestris, Nat. Prod. Commun., 4 Dubey, 2016, Phytochemical and biochemical studies of Jasminum officinale leaves, Int. J. Pharma Sci. Res., 7, 2632 El-Hawary, 2021, Phenolic profiling of different Jasminum species cultivated in Egypt and their antioxidant activity, Nat. Prod. Res., 35, 4663, 10.1080/14786419.2019.1700508 Gasparetto, 2011, Ethnobotanical and scientific aspects of Malva sylvestris L.: a millennial herbal medicine, J. Pharm. Pharmacol., 64, 172, 10.1111/j.2042-7158.2011.01383.x He, 2015, Phenolic compounds and antioxidant activities of edible flowers of Pyrus pashia, J. Funct.Foods, 17, 371, 10.1016/j.jff.2015.05.045 Hussain, 2013, Comparative in vitro study of antimicrobial activities of flower and whole plant of Jasminum officinale against some human pathogenic microbes, J. Alternative Compl. Med., 2, 33 Irfan, 2021, Phenolic and flavonoid contents in Malva sylvestris and exploration of active drugs as antioxidant and anti-COVID19 by quantum chemical and molecular docking studies, J. Saudi Chem. Soc., 25, 10.1016/j.jscs.2021.101277 Kaisoon, 2011, Phenolic compounds and antioxidant activities of edible flowers from Thailand, J. Funct.Foods, 3, 88, 10.1016/j.jff.2011.03.002 Khan, 2013, Antibacterial activity of some medicinal plants against selected human pathogenic bacteria, Eur. J. Microbiol. Immunol., 3, 272, 10.1556/EuJMI.3.2013.4.6 Khuri, 2017, Response surface methodology and its applications in agricultural and food sciences, Biom. Biostat. Int. J., 5, 155 Kumari, 2021, Phytochemicals from edible flowers: opening a new arena for healthy lifestyle, J. Funct.Foods, 78, 10.1016/j.jff.2021.104375 Lee, 2022, Protocatechuic acid protects hepatocytes against hydrogen peroxide-induced oxidative stress, Curr. Res. Nutr. Food Sci., 5, 222 Loizzo, 2016, Edible flowers: a rich source of phytochemicals with antioxidant and hypoglycemic properties, J. Agric. Food Chem., 64, 2467, 10.1021/acs.jafc.5b03092 Lupitu, 2018, Variation in phenolic content and antioxidant activity of different plant parts of Primula veris, Sci. Bull., Ser. F. Biotechnol., 22, 50 Mahran, 2019, Effect-directed analysis by high-performance thin-layer chromatography for bioactive metabolites tracking in Primula veris flower and Primula boveana leaf extracts, J. Chromatogr. A, 1605, 10.1016/j.chroma.2019.460371 Mani, 2018, Chrysin: sources, beneficial pharmacological activities, and molecular mechanism of action, Phytochemistry, 145, 187, 10.1016/j.phytochem.2017.09.016 Morsli, 2021, Appraisal of the combined effect of time and temperature on the total polyphenol yield in batch stirred-tank extraction of medicinal and aromatic plants: the extraction efficiency factor, Int. J. Appl. Res. Med. Plants, 25 Mousavi, 2020, Data on cytotoxic and antibacterial activity of synthesized Fe3O4 nanoparticles using Malva sylvestris, Data Brief, 28, 10.1016/j.dib.2019.104929 Naji, 2018 Nowicka, 2019, Anti-hyperglycemic and anticholinergic effects of natural antioxidant contents in edible flowers, Antioxidants, 8, 308, 10.3390/antiox8080308 Pereira, 2017, Influence of ripening stage on bioactive compounds and antioxidant activity in nine fig (Ficus carica L.) varieties grown in Extremadura, Spain, J. Food Compos. Anal., 64, 203, 10.1016/j.jfca.2017.09.006 Rama, 2013, Evaluation of flowers of Jasminum officinale for antibacterial activity, J. Adv. Pharm. Sci., 3, 428 Rashmi, 2020, Phenolic acids from vegetables: a review on processing stability and health benefits, Food Res. Int., 136, 10.1016/j.foodres.2020.109298 Semwal, 2021, Health benefits and limitations of rutin - a natural flavonoid with high nutraceutical value Phytochem, Lett, 46, 119 Singh, 2002, Studies on the antioxidant activity of pomegranate (Punica granatum) peel and seed extracts using in vitro models, J. Agric. Food Chem., 50, 81, 10.1021/jf010865b Singleton, 1965, Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents, Am. J. Enol. Vitic., 16, 144, 10.5344/ajev.1965.16.3.144 Sirichan, 2022, Optimization of ultrasound extraction of functional compound from makiang seed by response surface methodology and antimicrobial activity of optimized extract with its application in orange juice, Ultrason. Sonochem., 83, 10.1016/j.ultsonch.2022.105916 Srinivasulu, 2018, Syringic acid (SA) ‒ a review of its occurrence, biosynthesis, pharmacological and industrial importance, Biomed. Pharmacother., 108, 547, 10.1016/j.biopha.2018.09.069 Takahashi, 2020, Edible flowers: bioactive profile and its potential to be used in food development, Food Res. Int., 129, 10.1016/j.foodres.2019.108868 Tünde, 2015, 235 Ucar, 2019, The effects of vacuum and freeze-drying on the physicochemical properties and in vitro digestibility of phenolics in oyster mushroom (Pleurotus ostreatus), J. Food Meas. Char., 13, 2298, 10.1007/s11694-019-00149-w Yang, 2009, Extraction optimization of bioactive compounds (crocin, geniposide and total phenolic compounds) from Gardenia (Gardenia jasminoides Ellis) fruits with response surface methodology, Innovat. Food Sci. Emerg. Technol., 10, 610, 10.1016/j.ifset.2009.03.003 Zhang, 2018, Techniques for extraction and isolation of natural products: a comprehensive review, Chin. Med., 13, 20, 10.1186/s13020-018-0177-x Zhishen, 1999, The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals, Food Chem., 64, 555, 10.1016/S0308-8146(98)00102-2